Compounds for ESC/iPSC Proliferation and Renewal

Y-27632 dihydrochloride

Catalog #: 1254

(19)

Citations (1869)

Product Documents

Images (8)

Selective ROCK inhibitor; inhibits ROCK1 (p160 ROCK) and ROCK2; stem cell freezing (cryopreservation) media component

GMP Version Available: TB1254-GMP

GMP

Alternate Names:

y27632,Y-27632 2HCl,ROCK inhibitor,ROCK1 inhibitor

Chemical Name:

trans-4-[(1R)-1-Aminoethyl]-N-4-pyridinylcyclohexanecarboxamide dihydrochloride

Purity:

≥98%

SB 431542

Catalog #: 1614

(13)

Citations (2529)

Product Documents

Images (2)

Potent, selective inhibitor of TGF-βRI, ALK4 and ALK7

GMP Version Available: TB1614-GMP

GMP

Chemical Name:

4-[4-(1,3-benzodioxol-5-yl)-5-(2-pyridinyl)-1H-imidazol-2-yl]benzamide

Purity:

≥99%

Y-27632 dihydrochlorideGMP

Catalog #: TB1254-GMP

Citations (19)

Product Documents

Images (1)

Y-27632 synthesized to cGMP guidelines

Chemical Name:

trans-4-[(1R)-1-Aminoethyl]-N-4-pyridinylcyclohexanecarboxamide dihydrochloride

Purity:

≥99%

A 83-01

Catalog #: 2939

(12)

Citations (1154)

Product Documents

Images (6)

Selective inhibitor of TGF-βRI, ALK4 and ALK7

Chemical Name:

3-(6-Methyl-2-pyridinyl)-N-phenyl-4-(4-quinolinyl)-1H-pyrazole-1-carbothioamide

Purity:

≥98%

IWP 2

Catalog #: 3533

(3)

Citations (547)

Product Documents

Images (2)

PORCN inhibitor; inhibits Wnt processing and secretion

Chemical Name:

N-(6-Methyl-2-benzothiazolyl)-2-[(3,4,6,7-tetrahydro-4-oxo-3-phenylthieno[3,2-d]pyrimidin-2-yl)thio]-acetamide

Purity:

≥98%

LY 294002 hydrochloride

Catalog #: 1130

(7)

Citations (111)

Product Documents

Images (1)

Prototypical PI 3-kinase inhibitor; also inhibits other kinases

Chemical Name:

2-(4-Morpholinyl)-8-phenyl-4H-1-benzopyran-4-one hydrochloride

Purity:

≥99%

PD 98059

Catalog #: 1213

(5)

Citations (566)

Product Documents

Images (1)

MEK inhibitor

Chemical Name:

2-(2-Amino-3-methoxyphenyl)-4H-1-benzopyran-4-one

Purity:

≥98%

Chroman 1

Catalog #: 7163

Citations (34)

Product Documents

Images (1)

Highly potent and selective ROCK 2 inhibitor; improves cell survival after cryogenesis

Chemical Name:

(3S)-N-[2-[2-(Dimethylamino)ethoxy]-4-(1H-pyrazol-4-yl)phenyl]-3,4-dihydro-6-methoxy-2H-1-benzopyran-3-carboxamide dihydrochloride

Purity:

≥98%

SB 216763

Catalog #: 1616

Citations (251)

Product Documents

Images (1)

Potent, selective GSK-3 inhibitor

Chemical Name:

3-(2,4-Dichlorophenyl)-4-(1-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione

Purity:

≥98%

A 769662

Catalog #: 3336

Citations (123)

Product Documents

Images (1)

Potent AMPK activator

Chemical Name:

6,7-Dihydro-4-hydroxy-3-(2'-hydroxy[1,1'-biphenyl]-4-yl)-6-oxo-thieno[2,3-b]pyridine-5-carbonitrile

Purity:

≥98%

BIO

Catalog #: 3194

Citations (85)

Product Documents

Images (1)

Potent GSK-3 inhibitor; also inhibits cdks

Alternate Names:

6BIO

Chemical Name:

(2'Z,3'E)-6-Bromoindirubin-3'-oxime

Purity:

≥98%

Emricasan

Catalog #: 7310

Citations (5)

Product Documents

Images (1)

Potent pan-caspase inhibitor

Alternate Names:

IDN-6556,PF-03491390

Chemical Name:

N-[2-(1,1-Dimethylethyl)phenyl]-2-oxoglycyl-N-[(1S)-1-(carboxymethyl)-2-oxo-3-(2,3,5,6-tetrafluorophenoxy)propyl]-L-alaninamide

Purity:

≥98%

16,16-Dimethyl Prostaglandin E2

Catalog #: 4027

Citations (8)

Product Documents

Images (1)

Synthetic prostaglandin E2 (Cat. No. 2296) derivative; regulates HSC development

Chemical Name:

(5Z,11α,13E,15R)-11,15-Dihydroxy-16,16-dimethyl-9-oxo-prosta-5,13-dien-1oic acid

Purity:

≥95%

WH-4-023

Catalog #: 5413

Citations (20)

Product Documents

Images (1)

Potent and selective Lck and Src inhibitor; also inhibits SIK

Alternate Names:

KIN112

Chemical Name:

2,6-Dimethylphenyl-N-(2,4-dimethoxyphenyl)-N-[2-[[4-(4-methyl-1-piperazinyl)phenyl]amino]-4-pyrimidinyl]carbamate

Purity:

≥98%

Pyrintegrin

Catalog #: 4978

Citations (5)

Product Documents

Images (1)

Enhances survival of human ESCs following enzymatic dissociation

Chemical Name:

N-(Cyclopropylmethyl)-4-[[4-(3,4-dihydro-6-hydroxy-1(2H)-quinolinyl)-2-pyrimidinyl]amino]benzenesulfonamide

Purity:

≥98%

Surfen

Catalog #: 6634

Citations (1)

Product Documents

Images (1)

Heparin sulfate antagonist

Chemical Name:

N,N'-Bis(4-amino-2-methyl-6-quinolinyl)urea dihydrochloride

Purity:

≥98%

Y-27632 in solution

Catalog #: 7000

(1)

Product Documents

Images (2)

Sterile-filtered 10 mM solution of Y-27632, selective ROCK inhibitor, pre-dissolved in water

Chemical Name:

trans-4-[(1R)-1-Aminoethyl]-N-4-pyridinylcyclohexanecarboxamide dihydrochloride

Purity:

≥97%

CEPT Cocktail Kit

Catalog #: 7991

(1)

Citations (9)

Product Documents

Images (1)

Cell culture supplement for improving stem cell survival

Ac₄-8-keto-Neu5Ac n-pentyl esterNew

Catalog #: 7922

Product Documents

Images (1)

α2,8-linked polysialic acid biosynthesis attenuator

Alternate Names:

8-Keto-Neu5Ac

Chemical Name:

(S)-1-((2R,3R,4S,6R)-3-Acetamido-4,6-diacetoxy-6-((pentyloxy)carbonyl)tetrahydro-2H-pyran-2-yl)-2-oxopropane-1,3-diyl diacetate

Purity:

≥90%

Compounds for ESC/iPSC Proliferation and Renewal

Y-27632 dihydrochloride

SB 431542

Y-27632 dihydrochlorideGMP

A 83-01

IWP 2

LY 294002 hydrochloride

PD 98059

Chroman 1

SB 216763

A 769662

BIO

Emricasan

16,16-Dimethyl Prostaglandin E2

WH-4-023

Pyrintegrin

Surfen

Y-27632 in solution

CEPT Cocktail Kit

Ac₄-8-keto-Neu5Ac n-pentyl esterNew

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Compounds for ESC/iPSC Proliferation and Renewal

Y-27632 dihydrochloride

SB 431542

Y-27632 dihydrochlorideGMP

A 83-01

IWP 2

LY 294002 hydrochloride

PD 98059

Chroman 1

SB 216763

A 769662

BIO

Emricasan

16,16-Dimethyl Prostaglandin E2

WH-4-023

Pyrintegrin

Surfen

Y-27632 in solution

CEPT Cocktail Kit

Ac4-8-keto-Neu5Ac n-pentyl esterNew

Ac₄-8-keto-Neu5Ac n-pentyl esterNew