16 results for "Adenosine A2b R Small Molecules and Peptides" in Products
Adenosine A2b R: Small Molecules and Peptides
The Adenosine A2b Receptor (ADORA2B) gene codes for a receptor located on chromosome 17 (near the Smith-Magenis syndrome region) that initiates adenylyl cyclase in the presence of adenosine. The encoded adenoside receptor is 332 amino acids long, around 36 kDA, and is member to the G protein-coupled receptor superfamily and interacts with netrin-1 to promote axon elongation. ADORA2B has been associated with cholera, hepatitis B, breast cancer, carcinoma, eclampsia, ischemia, asthma, cystic fibrosis, astrocytoma, and atherosclerosis. It is involved in signal transduction IP3 signaling, GPCR ligand binding and signaling, and the methotrexate pathway through interactions with the EZR, NTN1, ADA, DDC, and SLC9A3R2 genes.
Endogenous adenosine receptor agonist
| Chemical Name: | 9-β-D-Ribofuranosyl-9H-purin-6-amine |
| Purity: | ≥98% (HPLC) |
High affinity adenosine agonist
| Alternate Names: | 5'-N-Ethylcarboxamidoadenosine |
| Chemical Name: | 1-(6-Amino-9H-purin-9-yl)-1-deoxy-N-ethyl-β-D-ribofuranuronamide |
| Purity: | ≥98% (HPLC) |
PDE inhibitor (non-selective)
| Chemical Name: | 3,7-Dihydro-1-methyl-3-(2-methylpropyl)-1H-purine-2,6-dione |
| Purity: | ≥98% (HPLC) |
Potent and highly selective A2A antagonist
| Chemical Name: | 4-(2-[7-Amino-2-(2-furyl)[1,2,4]triazolo[2,3-a][1,3,5]triazin-5-ylamino]ethyl)phenol |
| Purity: | ≥98% (HPLC) |
Potent partial A2B agonist; cardioprotective
| Chemical Name: | 2-[[6-Amino-3,5-dicyano-4-[4-(cyclopropylmethoxy)phenyl]-2-pyridinyl]thio]-acetamide |
| Purity: | ≥98% (HPLC) |
Potent adenosine receptor antagonist
| Chemical Name: | 9-Chloro-2-(2-furanyl)-[1,2,4]triazolo[1,5-c]quinazolin-5-amine |
| Purity: | ≥98% (HPLC) |
Potent adenosine A2A and A2B receptor partial agonist
| Chemical Name: | 2-Amino-4-(4-hydroxyphenyl)-6-[(1H-imidazol-2-ylmethyl)thio]-3,5-pyridinecarbonitrile |
| Purity: | ≥98% (HPLC) |
Selective A2B antagonist
| Chemical Name: | N-(4-Cyanophenyl)-2-[4-(2,3,6,7-tetrahydro-2,6-dioxo-1,3-dipropyl-1H-purin-8-yl)phenoxy]-acetamide |
| Purity: | ≥98% (HPLC) |
Selective human A2B antagonist; water-soluble
| Chemical Name: | 4-(2,3,6,7-Tetrahydro-2,6-dioxo-1-propyl-1H-purin-8-yl)-benzenesulfonic acid |
| Purity: | ≥98% (HPLC) |
A1 and A2B antagonist. CNS stimulant
| Chemical Name: | 3,7-Dihydro-1,3,7-trimethyl-1H-purine-2,6-dione |
| Purity: | ≥98% (HPLC) |
Adenosine receptor antagonist
| Chemical Name: | 2-[4-(2,3,6,7-Tetrahydro-2,6-dioxo-1,3-dipropyl-1H-purin-8-yl)phenoxy]-acetic acid |
| Purity: | ≥98% (HPLC) |
Highly selective A2B antagonist
| Chemical Name: | 8-[4-[4-(4-Chlorophenzyl)piperazide-1-sulfonyl)phenyl]]-1-propylxanthine |
| Purity: | ≥98% (HPLC) |
Adenosine receptor agonist
| Alternate Names: | 2-CADO |
| Chemical Name: | 6-Amino-2-chloropurine riboside |
| Purity: | ≥98% (HPLC) |
Adenosine receptor antagonist
| Alternate Names: | Xanthine amine congener |
| Chemical Name: | N-(2-Aminoethyl)-2-[4-(2,3,6,7-tetrahydro-2,6-dioxo-1,3-dipropyl-1H-purin-8-yl)phenoxy]-acetamide dihydrochloride |
| Purity: | ≥98% (HPLC) |
Selective A2B antagonist
| Chemical Name: | 8-[4-[4-(4-Chlorobenzyl)piperazide-1-sulfonyl)phenyl]]-1-propylxanthine |
| Purity: | ≥98% (HPLC) |
Selective A2B antagonist
| Alternate Names: | CVT 6883 |
| Chemical Name: | 3-Ethyl-3,9-dihydro-1-propyl-8-[1-[[3-(trifluoromethyl)phenyl]methyl]-1H-pyrazol-4-yl]-1H-purine-2,6-dione |
| Purity: | ≥98% (HPLC) |
