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PlGF Products
PlGF (placenta growth factor) is secreted primarily by villous trophoblasts and decidual cells, with circulating levels increasing during pregnancy but attenuated in preeclampsia. PlGF signals through VEGF R1/Flt‑1 and Neuropilins, while VEGF binds both VEGF R1 and R2 but signals mainly through VEGF R2. PlGF reduces binding of VEGF to VEGF R1 and increases VEGF/VEGF R2‑mediated angiogenesis. It induces monocyte activation, migration, and production of inflammatory cytokines and VEGF. These activities facilitate wound and bone fracture healing and also contribute to inflammation in active sickle cell disease and atherosclerosis.
21 results for "PlGF" in Products
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PlGF Products
PlGF (placenta growth factor) is secreted primarily by villous trophoblasts and decidual cells, with circulating levels increasing during pregnancy but attenuated in preeclampsia. PlGF signals through VEGF R1/Flt‑1 and Neuropilins, while VEGF binds both VEGF R1 and R2 but signals mainly through VEGF R2. PlGF reduces binding of VEGF to VEGF R1 and increases VEGF/VEGF R2‑mediated angiogenesis. It induces monocyte activation, migration, and production of inflammatory cytokines and VEGF. These activities facilitate wound and bone fracture healing and also contribute to inflammation in active sickle cell disease and atherosclerosis.
21 results for "PlGF" in Products
Design and order Simple Plex cartridges tailor made to meet your needs with customizable Simple Plex Assay panels for the Ella platform.
Luminex Discovery Assays provide the most flexible assays on the market. These panels are completely customizable using our large menu of human, mouse, and rat analytes, making them the perfect tool for biomarker discovery and screening.
Build your own Luminex Assay with our Luminex Assay Customization Tool.
Contains 4 membranes - each spotted in duplicate with 55 different angiogenesis antibodies
| Sensitivity : | 7 pg/mL |
| Assay Range : | 15.6 - 1,000 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma, Citrate Plasma, Urine) |
| Applications : | ELISA |
Simple Plex Human PIGF assay kit for use on Ella instrument. Contains cartridge, sample diluent SD13, and wash buffer.
Create your custom Simple Plex cartridge for up to 8 targets. Choose from more than 250 targets across multiple species.
| Assay Range : | 31.2 - 2,000 pg/mL |
| Applications : | ELISA |
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | ELISA Detection, Western Blot |
| Source : | E. coli |
| Accession # : | NP_001193941.1 |
| Applications : | Bioactivity |
| Sensitivity : | 0.326 pg/mL |
| Assay Range : | 3.13 - 200 pg/mL (Serum, EDTA Plasma, Heparin Plasma) |
| Applications : | ELISA |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #37203 |
| Applications : | ELISA Capture |
Recombinant Monoclonal Antibody.
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #37203R |
| Applications : | ELISA Capture |
| Clonality : | Monoclonal |
| Host : | Mouse IgG2a Clone #1038863 |
| Applications : | Block/Neutralize |
| Clonality : | Monoclonal |
| Host : | Mouse IgG2a Clone #146213 |
| Applications : | Western Blot |
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | Western Blot |
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | Western Blot |
| Clonality : | Polyclonal |
| Host : | Sheep IgG |
| Applications : | Immunohistochemistry |
| Clonality : | Monoclonal |
| Host : | Rat IgG2a Clone #358905 |
| Applications : | Immunohistochemistry |
| Clonality : | Monoclonal |
| Host : | Mouse IgG2b Clone #1038864 |
| Applications : | Immunocytochemistry/Immunofluorescence |
