PlGF: Antibodies
PlGF (placenta growth factor) is secreted primarily by villous trophoblasts and decidual cells, with circulating levels increasing during pregnancy but attenuated in preeclampsia. PlGF signals through VEGF R1/Flt‑1 and Neuropilins, while VEGF binds both VEGF R1 and R2 but signals mainly through VEGF R2. PlGF reduces binding of VEGF to VEGF R1 and increases VEGF/VEGF R2‑mediated angiogenesis. It induces monocyte activation, migration, and production of inflammatory cytokines and VEGF. These activities facilitate wound and bone fracture healing and also contribute to inflammation in active sickle cell disease and atherosclerosis.
11 results for "PlGF Primary Antibodies" in Products
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PlGF: Antibodies
PlGF (placenta growth factor) is secreted primarily by villous trophoblasts and decidual cells, with circulating levels increasing during pregnancy but attenuated in preeclampsia. PlGF signals through VEGF R1/Flt‑1 and Neuropilins, while VEGF binds both VEGF R1 and R2 but signals mainly through VEGF R2. PlGF reduces binding of VEGF to VEGF R1 and increases VEGF/VEGF R2‑mediated angiogenesis. It induces monocyte activation, migration, and production of inflammatory cytokines and VEGF. These activities facilitate wound and bone fracture healing and also contribute to inflammation in active sickle cell disease and atherosclerosis.
11 results for "PlGF Primary Antibodies" in Products
Clonality : | Polyclonal |
Host : | Goat IgG |
Applications : | ELISA Detection, Western Blot |
Clonality : | Monoclonal |
Host : | Mouse IgG1 Clone #37203 |
Applications : | ELISA Capture |
Recombinant Monoclonal Antibody.
Clonality : | Monoclonal |
Host : | Mouse IgG1 Clone #37203R |
Applications : | ELISA Capture |
Clonality : | Monoclonal |
Host : | Mouse IgG2a Clone #1038863 |
Applications : | Block/Neutralize |
Clonality : | Monoclonal |
Host : | Mouse IgG2a Clone #146213 |
Applications : | Western Blot |
Clonality : | Polyclonal |
Host : | Goat IgG |
Applications : | Western Blot |
Clonality : | Polyclonal |
Host : | Goat IgG |
Applications : | Western Blot |
Clonality : | Polyclonal |
Host : | Sheep IgG |
Applications : | Immunohistochemistry |
Clonality : | Monoclonal |
Host : | Rat IgG2a Clone #358905 |
Applications : | Immunohistochemistry |
Clonality : | Monoclonal |
Host : | Mouse IgG2b Clone #1038864 |
Applications : | Immunocytochemistry/Immunofluorescence |