Human PlGF Antibody
Catalog # MAB264 | R&D Systems, Inc. a Bio-Techne Brand
Key Product Details
Species Reactivity
Applications
Label
Antibody Source
Product Summary for Human PlGF Antibody
Immunogen
Ala21-Arg149
Accession # P49763
Specificity
Clonality
Host
Isotype
Applications for Human PlGF Antibody
Human PlGF Sandwich Immunoassay
Reviewed Applications
Read 2 reviews rated 5 using MAB264 in the following applications:
Published Applications
Read 4 publications using MAB264 in the following applications:
Formulation, Preparation and Storage
Purification
Reconstitution
Formulation
Shipping
Stability & Storage
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Background: PlGF
Placenta growth factor (PlGF) is a member of the vascular endothelial growth factor (VEGF) family of growth factors. As a result of alternative splicing, at least two PlGF mRNAs encoding monomeric PlGF precursors containing 149 and 170 amino acid residues have been described. The expression of PlGF is not widespread but has been detected in human umbilical vein endothelial cells, placenta, choriocarcinoma cell lines, and in renal cell carcinoma associated with angiogenesis. The PlGF proteins bind with high-affinity to VEGF R1/Flt-1 but not to VEGF R2/Flk-1.
Product Documents for Human PlGF Antibody
Product Specific Notices for Human PlGF Antibody
For research use only
Citations for Human PlGF Antibody (4)
Citations are publications that use Bio-Techne products. Selected citations for Human PlGF Antibody include:
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Species: Human
Sample Types: Whole Cells
Applications: Neutralization(2016-11-29), Hypoxia-induced responses by endothelial colony-forming cells are modulated by placental growth factor Stem Cell Res Ther, 2016-17(1):173.
PMID: 27899144 -
Species: Mouse
Sample Types: Matrigel Plug
Applications: NeutralizationPark et al. (2014-02-26), Interaction of mesenchymal stem cells with fibroblast-like synoviocytes via cadherin-11 promotes angiogenesis by enhanced secretion of placental growth factor. J Immunol, 2014-0192(7):3003-10.
PMID: 24574497 -
Species: Human
Sample Types: Whole Cells
Applications: NeutralizationHeijink IH et al. (2006-10-05), Der p, IL-4, and TGF-beta cooperatively induce EGFR-dependent TARC expression in airway epithelium. Am. J. Respir. Cell Mol. Biol., 2006-136(3):351-9.
PMID: 17023689 -
Species: Human
Sample Types: Whole Cells
Applications: NeutralizationCianfarani F et al. (2006-10-01), Placenta growth factor in diabetic wound healing: altered expression and therapeutic potential. Am. J. Pathol., 2006-1169(4):1167-82.
PMID: 17003476
There are no citations that match your criteria.
Customer Reviews for Human PlGF Antibody (2)
Customer Images
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Application: Immunocytochemistry/ImmunofluorescenceSample Tested: Endothelial colony-forming cellsSpecies: MouseVerified Customer | Posted 02/17/2021Cells were fixed in 4% paraformaldehyde for 20 min at room temperature. Following PBS washes, cells were permeabilised with 0.1% Triton X-100 for 10 min at RT and then blocked in 1% bovine serum albumin for 2 h in PBS before overnight incubation in primary antibody at 4 °C. After washing with PBS, cells were incubated with appropriate secondary antibody for 1 h at RT and imaged
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Application: ImmunohistochemistrySample Tested: Placental tissueSpecies: HumanVerified Customer | Posted 11/26/2020Human placenta were fixed in 4% paraformaldehyde. Tissue was embedded and 5 micron sections cut. Sections were permeabilized with PBS containing 0.1% Triton X-100, then blocked for 30 min in 3% BSA in PBS containing 0.1% Triton X-100. Goat Anti-Human PIGF Antigen was diluted in blocking buffer to 1:200 and applied to sections for 1 hour at RT. Sections were washed 3X with PBS containing 0.1% Triton X-100, then incubated with secondary antibody.
There are no reviews that match your criteria.
Reconstitution Calculator
The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.