Phosphodiesterase Inhibitors Small Molecules and Peptides

Gisadenafil besylate

Catalog #: 4165

Citations (2)

Product Documents

Images (1)

Potent PDE5 inhibitor; orally bioavailable

Alternate Names:

UK 369003

Chemical Name:

5-[2-Ethoxy-5-[(4-ethyl-1-piperazinyl)sulfonyl]-3-pyridinyl]-3-ethyl-2,6-dihydro-2-(2-methoxyethyl)-7H-pyrazolo[4,3-d]pyrimidin-7-one benzenesulfonate

Purity:

≥98%

Rolipram

Catalog #: 0905

Citations (161)

Product Documents

Images (1)

PDE4 inhibitor

Chemical Name:

4-(3-(Cyclopentyloxy)-4-methoxyphenyl)pyrrolidin-2-one

Purity:

≥98%

Ro 20-1724

Catalog #: 0415

Citations (33)

Product Documents

Images (1)

PDE4 inhibitor

Chemical Name:

4-(3-Butoxy-4-methoxyphenyl)methyl-2-imidazolidone

Purity:

≥98%

Enoximone

Catalog #: 1693

Citations (4)

Product Documents

Images (1)

PDE3 inhibitor

Chemical Name:

1,3-Dihydro-4-methyl-5-[4-(methylthio)benzoyl]-2H-imidazol-2-one

Purity:

≥98%

Zaprinast

Catalog #: 0947

Citations (47)

Product Documents

Images (1)

GPR35 agonist

Chemical Name:

2-(2-Propyloxyphenyl)-8-azapurin-6-one

Purity:

≥98%

Dipyridamole

Catalog #: 0691

(1)

Citations (30)

Product Documents

Images (1)

Adenosine transport inhibitor

Chemical Name:

2,6-bis(Diethanolamino)-4,8-dipiperidinopyrimido[5,4-d]pyrimidine

Purity:

≥98%

Cilostamide

Catalog #: 0915

Citations (58)

Product Documents

Images (1)

PDE3 inhibitor

Alternate Names:

OCP 3689

Chemical Name:

N-Cyclohexyl-N-methyl-4-(1,2-dihydro-2-oxo-6-quinolyloxy)butyramide

Purity:

≥97%

EHNA hydrochloride

Catalog #: 1261

Citations (40)

Product Documents

Images (1)

Adenosine deaminase inhibitor

Chemical Name:

erythro-9-(2-Hydroxy-3-nonyl)adenine hydrochloride

Purity:

≥98%

Caffeine

Catalog #: 2793

(3)

Citations (40)

Product Documents

Images (1)

A1 and A2B antagonist. CNS stimulant

Chemical Name:

3,7-Dihydro-1,3,7-trimethyl-1H-purine-2,6-dione

Purity:

≥98%

Dipyridamole

Catalog #: 0691

(1)

Citations (30)

Product Documents

Images (1)

Adenosine transport inhibitor

Chemical Name:

2,6-bis(Diethanolamino)-4,8-dipiperidinopyrimido[5,4-d]pyrimidine

Purity:

≥98%

(R)-(-)-Rolipram

Catalog #: 1349

Citations (12)

Product Documents

Images (1)

PDE4 inhibitor. More active enantiomer of rolipram (Cat. No. 0905)

Chemical Name:

(4R)-4-[3-(Cyclopentyloxy)-4-methoxyphenyl]pyrrolidin-2-one

Purity:

≥98%

Ibudilast

Catalog #: 1694

Citations (4)

Product Documents

Images (1)

PDE inhibitor (non-selective)

Alternate Names:

KC-404

Chemical Name:

2-Methyl-1-[2-(1-methylethyl)pyrazolo[1,5-a]pyridin-3-yl]-1-propanone

Purity:

≥98%

BRL 50481

Catalog #: 2237

Citations (16)

Product Documents

Images (1)

Selective PDE7 inhibitor

Chemical Name:

N,N,2-Trimethyl-5-nitro-benzenesulfonamide

Purity:

≥98%

Mesopram

Catalog #: 3053

Citations (1)

Product Documents

Images (1)

Orally active PDE4 inhibitor

Chemical Name:

(R)-5-(4-Methoxy-3-propoxyphenyl)-5-methyl-2-oxazolidinone

Purity:

≥98%

Piclamilast

Catalog #: 4525

Citations (4)

Product Documents

Images (1)

Potent and selective PDE4 inhibitor

Alternate Names:

RP 73401

Chemical Name:

3-(Cyclopentyloxy)-N-(3,5-dichloro-4-pyridinyl)-4-methoxybenzamide

Purity:

≥98%

Sildenafil citrate

Catalog #: 3784

Citations (6)

Product Documents

Images (1)

Potent PDE5 inhibitor; orally active

Chemical Name:

1-[[3-(4,7-Dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-5-yl)-4-ethoxyphenyl]sulfonyl]-4-methylpiperazine citrate

Purity:

≥98%

Deltarasin

Catalog #: 5424

Citations (3)

Product Documents

Images (1)

High affinity PDEδ-KRas interaction inhibitor; binds to PDEδ

Chemical Name:

2-[4-[(2S)-2-(2-Phenyl-1H-benzimidazol-1-yl)-2-(4-piperidinyl)ethoxy]phenyl]-1-(phenylmethyl)-1H-benzimidazole trihydrochloride

Purity:

≥98%

PF 04449613

Catalog #: 5915

Citations (1)

Product Documents

Images (1)

Potent PDE9 inhibitor; brain penetrant

Alternate Names:

PF 9613

Chemical Name:

1,5-Dihydro-6-[(1R)-1-(3-phenoxy-1-azetidinyl)ethyl]-1-(tetrahydro-2H-pyran-4-yl)-4H-pyrazolo[3,4-d]pyrimidin-4-one

Purity:

≥98%

PF 04671536 hydrochloride

Catalog #: 6024

Product Documents

Images (1)

Potent and selective PDE8B/8A inhibitor

Chemical Name:

5-Methyl-3-[[(2R)-4-(2-thiazolylmethyl)-2-morpholinyl]methyl]-3H-1,2,3-triazolo[4,5-d]pyrimidin-7-amine hydrochloride

Purity:

≥98%

Tadalafil

Catalog #: 6311

Citations (2)

Product Documents

Images (1)

Potent and highly selective PDE5 inhibitor; orally bioavailable

Alternate Names:

GF196960

Chemical Name:

(6R,12aR)-6-(1,3-Benzodioxol-5-yl)-2,3,6,7,12,12a-hexahydro-2-methylpyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione

Purity:

≥98%

A 33

Catalog #: 6313

Citations (4)

Product Documents

Images (1)

Potent and selective PDE4B inhibitor

Chemical Name:

2-[4-[[2-(5-Chloro-2-thienyl)-5-ethyl-6-methyl-pyrimidin-4-yl]amino]phenyl]acetic acid

Purity:

≥98%

A 33

Catalog #: 6313

Citations (4)

Product Documents

Images (1)

Potent and selective PDE4B inhibitor

Chemical Name:

2-[4-[[2-(5-Chloro-2-thienyl)-5-ethyl-6-methyl-pyrimidin-4-yl]amino]phenyl]acetic acid

Purity:

≥98%

Phosphodiesterase Inhibitors Small Molecules and Peptides

Gisadenafil besylate

Rolipram

Ro 20-1724

Enoximone

Zaprinast

Dipyridamole

Cilostamide

EHNA hydrochloride

Caffeine

Dipyridamole

(R)-(-)-Rolipram

Ibudilast

BRL 50481

Mesopram

Piclamilast

Sildenafil citrate

Deltarasin

PF 04449613

PF 04671536 hydrochloride

Tadalafil

A 33

A 33

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