Ro 20-1724

Tocris Bioscience, part of Bio-Techne | Catalog # 0415

PDE4 inhibitor
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Key Product Details

Description

PDE4 inhibitor

View all Phosphodiesterase Inhibitors »

Product Description

Ro 20-1724 is a widely used inhibitor of cyclic nucleotide phosphodiesterase, selective for PDE4 (IC50 = 2.0 μM).

Product Specifications

Molecular Weight

278.35

Formula

C15H22N2O3

Storage

Store at RT

Purity

≥98% (HPLC)

Chemical Name

4-(3-Butoxy-4-methoxyphenyl)methyl-2-imidazolidone

CAS Number

29925-17-5

PubChem ID

5087

InChI Key

PDMUULPVBYQBBK-UHFFFAOYSA-N

SMILES

CCCCOC1=CC(CC2CNC(=O)N2)=CC=C1OC

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 27.84 100
Ethanol 27.84 100

Preparing Stock Solutions for Ro 20-1724

The following data is based on the product molecular weight 278.35

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 3.59 mL 17.96 mL 35.93 mL
5 mM 0.72 mL 3.59 mL 7.19 mL
10 mM 0.36 mL 1.80 mL 3.59 mL
50 mM 0.07 mL 0.36 mL 0.72 mL

Calculators

Molarity Calculator

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Dilution Calculator

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Reconstitution Calculator

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Background References

References are publications that support the biological activity of the product.

Product Documents for Ro 20-1724

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Ro 20-1724

For research use only

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