Mesopram

Tocris Bioscience, part of Bio-Techne | Catalog # 3053

Orally active PDE4 inhibitor
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Key Product Details

Description

Orally active PDE4 inhibitor

View all Phosphodiesterase Inhibitors »

Product Description

Mesopram is an orally active phosphodiesterase (PDE) 4 inhibitor. Inhibits Th1 cell proliferation and decreases production of IFN-γ, TNF-α, IL-10 and iNOS in vitro. Triggers ovulation and exhibits efficacy against experimental autoimmune encephalomyelitis and murine colitis in vivo.

Product Specifications

Molecular Weight

265.31

Formula

C14H19NO4

Storage

Store at +4°C

Purity

≥98% (HPLC)

Chemical Name

(R)-5-(4-Methoxy-3-propoxyphenyl)-5-methyl-2-oxazolidinone

CAS Number

189940-24-7

PubChem ID

449190

InChI Key

PCCPERGCFKIYIS-AWEZNQCLSA-N

SMILES

O=C1O[C@@](C2=CC(OCCC)=C(OC)C=C2)(C)CN1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 26.53 100
Ethanol 26.53 100

Preparing Stock Solutions for Mesopram

The following data is based on the product molecular weight 265.31

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 3.77 mL 18.85 mL 37.69 mL
5 mM 0.75 mL 3.77 mL 7.54 mL
10 mM 0.38 mL 1.88 mL 3.77 mL
50 mM 0.08 mL 0.38 mL 0.75 mL

Calculators

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Reconstitution Calculator

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Background References

References are publications that support the biological activity of the product.

Product Documents for Mesopram

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Mesopram

For research use only

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