Rolipram

Tocris Bioscience, part of Bio-Techne | Catalog # 0905

PDE4 inhibitor
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Key Product Details

Description

PDE4 inhibitor

View all Phosphodiesterase Inhibitors »

Product Description

Rolipram is a selective inhibitor of cAMP phosphodiesterase (PDE4) (IC50 = 2.0 μM). Discriminates between two conformational states of PDE4 isoenzymes.

R-enantiomer also available.

Product Specifications

Molecular Weight

275.35

Formula

C16H21NO3

Storage

Store at RT

Purity

≥98% (HPLC)

Chemical Name

4-(3-(Cyclopentyloxy)-4-methoxyphenyl)pyrrolidin-2-one

CAS Number

61413-54-5

PubChem ID

5092

InChI Key

HJORMJIFDVBMOB-UHFFFAOYSA-N

SMILES

COC1=CC=C(C=C1OC1CCCC1)C1CNC(=O)C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 20.65 75
Ethanol 20.65 75

Preparing Stock Solutions for Rolipram

The following data is based on the product molecular weight 275.35

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.75 mM 4.84 mL 24.21 mL 48.42 mL
3.75 mM 0.97 mL 4.84 mL 9.68 mL
7.5 mM 0.48 mL 2.42 mL 4.84 mL
37.5 mM 0.10 mL 0.48 mL 0.97 mL

Calculators

Molarity Calculator

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Dilution Calculator

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Reconstitution Calculator

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Product Documents for Rolipram

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Rolipram

For research use only

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