Key Product Details
Description: | PDE4 inhibitor |
Chemical Name: | 4-(3-(Cyclopentyloxy)-4-methoxyphenyl)pyrrolidin-2-one |
Purity: | ≥98% (HPLC) |
Molecular Weight: | 275.35 |
Complete Your Research
Complete Your Experiment
Citations for Rolipram (20)
Citations are publications that use Bio-Techne products. Selected citations for Rolipram include:
-
Franchini et al.
(2019)
Linking NMDA Receptor Synaptic Retention to Synaptic Plasticity and Cognition.
iScience.
19:927
PMID: 31518901 -
Russo et al.
(2018)
Leucine-rich repeat kinase 2 controls protein kinase A activation state through phosphodiesterase 4.
J Neuroinflammation.
15:297
PMID: 30368241 -
Ikezu et al.
(2018)
Tau Phosphorylation is Impacted by Rare AKAP9 Mutations Associated with Alzheimer Disease in African Americans.
J Neuroimmune Pharmacol.
13:254
PMID: 29516269 -
Parnell et al.
(2015)
Phosphorylation of ezrin on Thr567 is required for the synergistic activation of cell spreading by EPAC1 and protein kinase A in HEK293T cells.
Eneuro.
1853:1749
PMID: 25913012 -
Polito et al.
(2015)
Selective Effects of PDE10A Inhibitors on Striatopallidal Neurons Require Phosphatase Inhibition by DARPP-32(1,2,3).
J Neurosci.
2
PMID: 26465004 -
Zhu et al.
(2015)
Different patterns of electrical activity lead to long-term potentiation by activating different intracellular pathways.
J Neurosci.
35:621
PMID: 25589756 -
Choi et al.
(2015)
PDE-4 inhibition rescues aberrant synaptic plasticity in Drosophila and mouse models of fragile X syndrome.
Pharmacol Res Perspect.
35:396
PMID: 25568131 -
Pecha et al.
(2015)
β 1 Adrenoceptor antagonistic effects of the supposedly selective β 2 adrenoceptor antagonist ICI 118,551 on the positive inotropic effect of adrenaline in murine hearts.
PLoS One.
3:e00168
PMID: 26516580 -
Merino et al.
(2015)
Glucagon Increases Beating Rate but Not Contractility in Rat Right Atrium. Comparison with isoprote.
PLoS One.
10:e0132884
PMID: 26222156 -
Ørstavik et al.
(2015)
The inotropic effect of the active metabolite of levosimendan, OR-1896, is mediated through inhibition of PDE3 in rat ventricular myocardium.
J Biol Chem.
10:e0115547
PMID: 25738589 -
Lundegaard et al.
(2015)
MEK Inhibitors Reverse cAMP-Mediated Anxiety in Zebrafish.
Chem Biol.
22:1335
PMID: 26388333 -
Orru et al.
(2013)
Psychostimulant pharmacological profile of paraxanthine, the main metabolite of caffeine in humans.
Neuropharmacology.
67:476
PMID: 23261866 -
Townsend and Emala
(2013)
Quercetin acutely relaxes airway smooth muscle and potentiates β-agonist-induced relaxation via dual phosphodiesterase inhibition of PLCβ and PDE4.
Am J Physiol Lung Cell Mol Physiol.
305:L396
PMID: 23873842 -
Adderley et al.
(2012)
Phosphodiesterases Regulate BAY 41-2272-Induced VASP Phosphorylation in Vascular Smooth Muscle Cells.
Front Pharmacol.
3:10
PMID: 22347188 -
Zhong et al.
(2012)
Phosphodiesterase 4 inhibition impairs cocaine-induced inhibitory synaptic plasticity and conditioned place preference.
Neuropsychopharmacology.
37:2377
PMID: 22713909 -
Adderley et al.
(2011)
Inhibition of ATP release from erythrocytes: a role for EPACs and PKC.
Microcirculation.
18:128
PMID: 21166931 -
Morales-Garcia et al.
(2011)
Phosphodiesterase 7 inhibition preserves DArgic neurons in cellular and rodent models of Parkinson disease.
PLoS One.
6:e17240
PMID: 21390306 -
Schapitz et al.
(2010)
Neuroligin 1 is dynamically exchanged at postsynaptic sites.
Biochim Biophys Acta.
30:12733
PMID: 20861378 -
Hosoi et al.
(2002)
Identification of a novel human eicosanoid receptor coupled to G(i/o).
J Pharmacol Exp Ther.
277:31459
PMID: 12065583 -
Haynes
(2000)
A(2A) adenosine receptor mediated potassium channel activation in rat epididymal smooth muscle.
Br J Pharmacol.
130:685
PMID: 10821799
There are no citations that match your criteria.