Small Molecules and Peptides (22)
Small Molecules (22)
Antagonist (21)
Other (1)
5 (6)
4 & up (8)
Tocris Bioscience (22)
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22 results for "P2X Receptor Antagonists Small Molecules and Peptides" in Products

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P2X Receptor Antagonists Small Molecules and Peptides

A 438079 hydrochloride
Catalog #: 2972
Citations (56)
Product Documents
Images (1)

Competitive P2X7 antagonist

Chemical Name:
3-[[5-(2,3-Dichlorophenyl)-1H-tetrazol-1-yl]methyl]pyridine hydrochloride
Purity:
≥98%
Competitive P2X7 antagonist
Catalog #
Availability
Size / Price
Qty
2972/10
2972/50
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Evans Blue tetrasodium salt
Catalog #: 0845
(2)
Citations (8)
Product Documents
Images (1)

Dye for assessing cell viability and blood brain barrier permeability; also EAAT inhibitor and iGluR antagonist

Chemical Name:
6,6-[(3,3'-Dimethyl[1,1'-biphenyl]-4,4'-diyl)bis(azo)bis[4-amino- 5-hydroxy-1,3-naphthalenedisulphonic acid] tetrasodium salt
Purity:
≥90%
Dye for assessing cell viability and blood brain barrier permeability; also EAAT inhibitor and iGluR antagonist
Catalog #
Availability
Size / Price
Qty
0845/1G
Bulk Order

A 740003
Catalog #: 3701
Citations (105)
Product Documents
Images (1)

Potent and selective P2X7 antagonist

Chemical Name:
N-[1-[[(Cyanoamino)(5-quinolinylamino)methylene]amino]-2,2-dimethylpropyl]-3,4-dimethoxybenzeneacetamide
Purity:
≥97%
Potent and selective P2X7 antagonist
Catalog #
Availability
Size / Price
Qty
3701/10
3701/50
Bulk Order

NF 279
Catalog #: 1199
Citations (48)
Product Documents
Images (1)

Potent and selective P2X1 antagonist

Chemical Name:
8,8'-[Carbonylbis(imino-4,1-phenylenecarbonylimino-4,1-phenylenecarbonylimino)]bis-1,3,5-naphthalenetrisulfonic acid hexasodium salt
Purity:
≥95%
Potent and selective P2X1 antagonist
Catalog #
Availability
Size / Price
Qty
1199/10
1199/50
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KN-62
Catalog #: 1277
(1)
Citations (164)
Product Documents
Images (1)

Non-competitive P2X7 antagonist

Chemical Name:
4-[(2S)-2-[(5-isoquinolinylsulfonyl)methylamino]-3-oxo-3-(4-phenyl-1-piperazinyl)propyl] phenyl isoquinolinesulfonic acid ester
Purity:
≥98%
Non-competitive P2X7 antagonist
Catalog #
Availability
Size / Price
Qty
1277/1
Bulk Order

NF 449
Catalog #: 1391
Citations (114)
Product Documents
Images (1)

Highly selective P2X1 antagonist

Chemical Name:
4,4',4'',4'''-[Carbonylbis(imino-5,1,3-benzenetriyl-bis(carbonylimino))]tetrakis-1,3-benzenedisulfonic acid, octasodium salt
Purity:
≥90%
Highly selective P2X1 antagonist
Catalog #
Availability
Size / Price
Qty
1391/10
1391/50
Bulk Order

TNP-ATP triethylammonium salt
Catalog #: 2464
Citations (19)
Product Documents
Images (1)

Potent and selective P2X antagonist

Chemical Name:
2',3'-O-(2,4,6-Trinitrophenyl)adenosine-5'-triphosphate tetra(triethylammonium) salt
Purity:
≥95%
Potent and selective P2X antagonist
Catalog #
Availability
Size / Price
Qty
2464/5
Bulk Order

AZ 11645373
Catalog #: 3317
Citations (29)
Product Documents
Images (1)

Potent and selective human P2X7 antagonist

Chemical Name:
3-[1-[[(3'-Nitro[1,1'-biphenyl]-4-yl)oxy]methyl]-3-(4-pyridinyl)propyl]-2,4-thiazolidinedione
Purity:
≥98%
Potent and selective human P2X7 antagonist
Catalog #
Availability
Size / Price
Qty
3317/50
3317/10
Bulk Order

AZ 10606120 dihydrochloride
Catalog #: 3323
Citations (16)
Product Documents
Images (1)

Potent P2X7 antagonist

Chemical Name:
N-[2-[[2-[(2-Hydroxyethyl)amino]ethyl]amino]-5-quinolinyl]-2-tricyclo[3.3.1.13,7]dec-1-ylacetamide dihydrochloride
Purity:
≥98%
Potent P2X7 antagonist
Catalog #
Availability
Size / Price
Qty
3323/10
3323/50
Bulk Order

5-BDBD
Catalog #: 3579
(1)
Citations (117)
Product Documents
Images (1)

Potent and selective P2X4 antagonist

Chemical Name:
5-(3-Bromophenyl)-1,3-dihydro-2H-benzofuro[3,2-e]-1,4-diazepin-2-one
Purity:
≥98%
Potent and selective P2X4 antagonist
Catalog #
Availability
Size / Price
Qty
3579/50
3579/10
Bulk Order

Suramin hexasodium salt
Catalog #: 1472
(3)
Citations (47)
Product Documents
Images (1)

Non-selective P2 antagonist

Chemical Name:
8,8'-[Carbonylbis[imino-3,1-phenylenecarbonylimino(4-methyl-3,1-phenylene)carbonylimino]]bis-1,3,5-naphthalenetrisulfonic acid hexasodium salt
Purity:
≥98%
Non-selective P2 antagonist
Catalog #
Availability
Size / Price
Qty
1472/50
Bulk Order

NF 157
Catalog #: 2450
Citations (51)
Product Documents
Images (1)

Selective P2Y11 and P2X1 antagonist

Chemical Name:
8,8'-[Carbonylbis[imino-3,1-phenylenecarbonylimino(4-fluoro-3,1-phenylene)carbonylimino]]bis-1,3,5-naphthalenetrisulfonic acid hexasodium salt
Purity:
≥90%
Selective P2Y11 and P2X1 antagonist
Catalog #
Availability
Size / Price
Qty
2450/10
Bulk Order

A 804598
Catalog #: 4473
(1)
Citations (33)
Product Documents
Images (1)

Potent and selective P2X7 antagonist

Chemical Name:
N-Cyano-N"-[(1S)-1-phenylethyl]-N'-5-quinolinyl-guanidine
Purity:
≥98%
Potent and selective P2X7 antagonist
Catalog #
Availability
Size / Price
Qty
4473/50
4473/10
Bulk Order

PPADS tetrasodium salt
Catalog #: 0625
(2)
Citations (42)
Product Documents
Images (1)

Non-selective P2 antagonist

Chemical Name:
Pyridoxalphosphate-6-azophenyl-2',4'-disulfonic acid tetrasodium salt
Non-selective P2 antagonist
Catalog #
Availability
Size / Price
Qty
0625/10
0625/50
Bulk Order

NF 023
Catalog #: 1240
Citations (37)
Product Documents
Images (1)

Selective and competitive P2X1 antagonist

Chemical Name:
8,8'-[carbonylbis(imino-3,1-phenylenecarbonylimino)]bis-1,3,5-naphthalene-trisulphonic acid, hexasodium salt
Selective and competitive P2X1 antagonist
Catalog #
Availability
Size / Price
Qty
1240/10
1240/50
Bulk Order

JNJ 47965567
Catalog #: 5299
(3)
Citations (36)
Product Documents
Images (1)

Potent and selective P2X7 antagonist; brain penetrant

Chemical Name:
2-(Phenylthio)-N-[[tetrahydro-4-(4-phenyl-1-piperazinyl)-2H-pyran-4-yl]methyl-3-pyridinecarboxamide
Purity:
≥98%
Potent and selective P2X7 antagonist; brain penetrant
Catalog #
Availability
Size / Price
Qty
5299/50
5299/10
Bulk Order

BX 430
Catalog #: 5545
Citations (9)
Product Documents
Images (1)

Selective P2X4 allosteric antagonist

Chemical Name:
N-[2,6-Dibromo-4-(1-methylethyl)phenyl]-N'-(3-pyridinyl)urea
Purity:
≥98%
Selective P2X4 allosteric antagonist
Catalog #
Availability
Size / Price
Qty
5545/50
5545/10
Bulk Order

iso-PPADS tetrasodium salt
Catalog #: 0683
(1)
Citations (7)
Product Documents
Images (1)

Non-selective P2X antagonist

Chemical Name:
Pyridoxalphosphate-6-azophenyl-2',5'-disulfonic acid tetrasodium salt
Non-selective P2X antagonist
Catalog #
Availability
Size / Price
Qty
0683/10
0683/50
Bulk Order

NF 110
Catalog #: 2548
Citations (22)
Product Documents
Images (1)

Potent P2X3 antagonist

Chemical Name:
4,4',4'',4'''-[Carbonylbis[imino-5,1,3-benzenetriylbis(carbonylimino)]]tetrakisbenzenesulfonic acid tetrasodium salt
Purity:
≥90%
Potent P2X3 antagonist
Catalog #
Availability
Size / Price
Qty
2548/10
2548/50
Bulk Order

RO-3
Catalog #: 3052
Citations (6)
Product Documents
Images (1)

Selective P2X3 and P2X2/3 antagonist

Chemical Name:
5-[[4,5-Dimethoxy-2-(methylethyl)phenyl]methyl]-2,4-pyrimidinediamine
Purity:
≥98%
Selective P2X3 and P2X2/3 antagonist
Catalog #
Availability
Size / Price
Qty
3052/10
Bulk Order

A 317491 sodium salt
Catalog #: 6493
Citations (1)
Product Documents
Images (1)

Selective, high affinity P2X3 and P2X2/3 antagonist; antinociceptive

Chemical Name:
5-[[[(3-Phenoxyphenyl)methyl][(1S)-1,2,3,4-tetrahydro-1-naphthalenyl]amino]carbonyl]-1,2,4-benzenetricarboxylic acid disodium salt
Purity:
≥98%
Selective, high affinity P2X3 and P2X2/3 antagonist; antinociceptive
Catalog #
Availability
Size / Price
Qty
6493/25
6493/5
Bulk Order

BAY 1797
Catalog #: 7573
Citations (1)
Product Documents
Images (1)

Selective P2X4 antagonist

Chemical Name:
N-[3-(Aminosulfonyl)-4-(3-chlorophenoxy)phenyl]benzeneacetamide
Purity:
≥98%
Selective P2X4 antagonist
Catalog #
Availability
Size / Price
Qty
7573/10
7573/50
Bulk Order
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