Key Product Details
Description: | Potent and selective P2X7 antagonist |
Chemical Name: | N-Cyano-N"-[(1S)-1-phenylethyl]-N'-5-quinolinyl-guanidine |
Purity: | ≥99% (HPLC) |
Molecular Weight: | 315.37 |
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Citations for A 804598 (2)
Citations are publications that use Bio-Techne products. Selected citations for A 804598 include:
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Dosch et al.
(2019)
Connexin-43-dependent ATP release mediates macrophage activation during sepsis.
Elife.
8
PMID: 30735126 -
Young et al.
(2015)
A novel mechanism of autophagic cell death in dystrophic muscle regulated by P2RX7 receptor large-pore formation and HSP90.
Cell Commun Signal.
11:113
PMID: 25700737
There are no citations that match your criteria.
Customer Reviews for A 804598 (1)
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Species: MouseAssay Type: In VitroCell Line/Tissue: MacrophagesRAW macrophages were stimulated with LPS (200 ng/ml) in the absence or presence of A 804598 (1 μM) or MRS 2578 (100 μM) for 8 h to follow iNOS expression by qPCR. Both compounds inhibited LPS-induced iNOS expression revealing role of purinergic receptors.
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