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A 804598

Tocris Bioscience a Bio-Techne Brand

A 804598 | CAS No. 1125758-85-1 | Potent and selective P2X7 antagonist
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Key Product Details

Description: Potent and selective P2X7 antagonist
Chemical Name: N-Cyano-N"-[(1S)-1-phenylethyl]-N'-5-quinolinyl-guanidine
Purity: ≥99% (HPLC)
Molecular Weight: 315.37

Citations for A 804598 (2)

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  • A 804598 inhibits LPS-induced inflammation
    Name: Anonymous
    Species: Mouse
    Assay Type: In Vitro
    Cell Line/Tissue: Macrophages
    RAW macrophages were stimulated with LPS (200 ng/ml) in the absence or presence of A 804598 (1 μM) or MRS 2578 (100 μM) for 8 h to follow iNOS expression by qPCR. Both compounds inhibited LPS-induced iNOS expression revealing role of purinergic receptors.
    A 804598 Serum 4473

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Product Documents for A 804598

Certificate of Analysis

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