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mGluR1 Products
Metabotropic glutamate receptor 1 (mGluR1) is a 130 kDa, 7-transmembrane glycoprotein that belongs to group I of the C-family of G-protein coupled receptors. On neurons, mGluR1 is postsynaptic, associates with Gq-like proteins, mobilizes intracellular Ca++, and influences ion channel activity. Mature mGluR1 is 1176 amino acids (aa) in length and contains a 574 aa N-terminal extracellular domain (ECD) (aa 19-592). The ECD binds glutamate and forms either a covalent homodimer or heterodimer with CaSR. There is one alternative splice form for human mGluR1 that shows a 20 aa substitution for the C-terminal 308 amino acids. Over aa 33-522, human mGluR1 shares more that 98% aa identity with mouse, rat and canine mGluR1.
31 results for "mGluR1" in Products
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mGluR1 Products
Metabotropic glutamate receptor 1 (mGluR1) is a 130 kDa, 7-transmembrane glycoprotein that belongs to group I of the C-family of G-protein coupled receptors. On neurons, mGluR1 is postsynaptic, associates with Gq-like proteins, mobilizes intracellular Ca++, and influences ion channel activity. Mature mGluR1 is 1176 amino acids (aa) in length and contains a 574 aa N-terminal extracellular domain (ECD) (aa 19-592). The ECD binds glutamate and forms either a covalent homodimer or heterodimer with CaSR. There is one alternative splice form for human mGluR1 that shows a 20 aa substitution for the C-terminal 308 amino acids. Over aa 33-522, human mGluR1 shares more that 98% aa identity with mouse, rat and canine mGluR1.
31 results for "mGluR1" in Products
| Clonality : | Monoclonal |
| Host : | Mouse IgG2a Clone #511601 |
| Applications : | CyTOF-ready, Flow Cytometry |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #511601 |
| Applications : | Flow Cytometry |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #511601 |
| Applications : | Flow Cytometry |
| Clonality : | Monoclonal |
| Host : | Mouse IgG2b Clone #1059503 |
| Applications : | Immunohistochemistry |
| Clonality : | Polyclonal |
| Host : | Rabbit IgG |
| Applications : | Immunohistochemistry, Western Blot |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #511601 |
| Applications : | Flow Cytometry |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #511601 |
| Applications : | Flow Cytometry |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #511601 |
| Applications : | Flow Cytometry |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #511601 |
| Applications : | Flow Cytometry |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #511601 |
| Applications : | Flow Cytometry |
mGlu1 inverse agonist
| Chemical Name : | (3aS,6aS)-Hexahydro-5-methylene-6a-(2-naphthalenylmethyl)-1H-cyclopenta[c]furan-1-one |
| Purity : | ≥98% (HPLC) |
AMPA agonist; also group I mGlu agonist
| Chemical Name : | (L)-(+)-α-Amino-3,5-dioxo-1,2,4-oxadiazolidine-2-propanoic acid |
| Purity : | ≥99% (HPLC) |
Potent group I mGlu antagonist
| Chemical Name : | N-Phenyl-7-(hydroxyimino)cyclopropa[b]chromen-1a-carboxamide |
| Purity : | ≥98% (HPLC) |
Selective mGlu1a antagonist
| Chemical Name : | (S)-(+)-α-Amino-4-carboxy-2-methylbenzeneacetic acid |
| Purity : | ≥99% (HPLC) |
| Clonality : | Polyclonal |
| Host : | Sheep IgG |
| Applications : | Western Blot |
| Clonality : | Polyclonal |
| Host : | Rabbit IgG |
| Applications : | Immunohistochemistry, Western Blot |
Potent and selective group I mGlu antagonist
| Alternate Names : | UPF 523 |
| Chemical Name : | (RS)-1-Aminoindan-1,5-dicarboxylic acid |
| Purity : | ≥98% (HPLC) |
Selective non-competitive mGlu1 antagonist
| Chemical Name : | 7-(Hydroxyimino)cyclopropa[b]chromen-1a-carboxylate ethyl ester |
| Purity : | ≥99% (HPLC) |
| Clonality : | Monoclonal |
| Host : | Mouse IgG2a Clone #511622 |
| Applications : | Immunohistochemistry |
Glucosidase α inhibitor (intestinal)
| Alternate Names : | Bay-g 5421 |
| Chemical Name : | O-4,6-Dideoxy-4-[[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)-2-cyclohexen-1-yl]amino]-α-D-glucopyranosyl-(1-4)-O-α-D-glucopyranosyl-(1-4)-D-Glucose |
Active metabolite of oxcarbazepine (Cat. No. 3864)
| Alternate Names : | GP 47779 |
| Chemical Name : | 10,11-Dihydro-10-hydroxy-5H-dibenz(Z)[b,f]azepin-5-carboxamide |
| Purity : | ≥98% (HPLC) |
Group I mGlu antagonist
| Chemical Name : | N-tricyclo[3.3.1.13,7]dec-1-yl-2-quinoxalinecarboxamide |
| Purity : | ≥99% (HPLC) |
Selective mGlu1 antagonist
| Alternate Names : | MPMQ hydrochloride |
| Chemical Name : | 6-Methoxy-N-(4-methoxyphenyl)-4-quinazolinamine hydrochloride |
| Purity : | ≥99% (HPLC) |
Potent and selective negative allosteric modulator of mGlu1 receptors; also mGlu1 inverse agonist
| Chemical Name : | 4-[1-(2-Fluoro-3-pyridinyl)-5-methyl-1H-1,2,3-triazol-4-yl]-3,6-dihydro-N-methyl-N-(1-methylethyl)-1(2H)-pyridinecarboxamide |
| Purity : | ≥98% (HPLC) |
