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467 results for "MDM2/HDM2" in Products
MDM2/HDM2 Products
MDM2 is a key regulator of p53 tumor suppressor protein activity and stability. MDM2 binds to and inhibits the transactivation domain of p53. In addition, MDM2 controls p53 stability by functioning as its E3 ligase in ubiquitination and by shuttling p53 from the nucleus to the cytoplasm for subsequent degradation. The importance of the p53/MDM2 relationship is underscored by the existence of an autoregulatory feedback loop whereby activated p53 transcriptionally upregulates the expression of its own inhibitor, MDM2.
Reactivity:
Human, Mouse, Rat
Details:
Mouse IgG1 kappa Monoclonal Clone #SMP14
Applications:
IHC, WB, IP
![Western Blot: MDM2/HDM2 Antibody (SMP14)BSA Free [NB100-2736]](https://resources.rndsystems.com/images/products/MDM2-HDM2-Antibody-SMP14-Western-Blot-NB100-2736-img0001.jpg "Western Blot: MDM2/HDM2 Antibody (SMP14)BSA Free [NB100-2736]")
Reactivity:
Human, Mouse, Rat
Details:
Rabbit IgG Polyclonal
Applications:
IHC, WB
Reactivity:
Human
Details:
Mouse IgG2B Monoclonal Clone #197702
Applications:
IP
Reactivity:
Human, Mouse, Rat
Details:
Mouse IgG1 kappa Monoclonal Clone #SMP14
Applications:
IHC, WB, IP
![Western Blot: MDM2/HDM2 Antibody (SMP14)Azide and BSA Free [NBP2-80845]](https://resources.rndsystems.com/images/products/MDM2-HDM2-Antibody-SMP14-Azide-and-BSA-Free-Western-Blot-NBP2-80845-img0001.jpg "Western Blot: MDM2/HDM2 Antibody (SMP14)Azide and BSA Free [NBP2-80845]")
Chemical Name:
(±)-4-[4,5-Bis(4-chlorophenyl)-2-(2-isopropoxy-4-methoxy-phenyl)-4,5-dihydro-imidazole-1-carbonyl]-piperazin-2-one
Purity:
≥98%
Reactivity:
Human, Mouse
Details:
Rabbit IgG Polyclonal
Applications:
IHC, WB, ICC/IF, IP, ChIP
![Western Blot: MDM2/HDM2 Antibody [NBP2-17247]](https://resources.rndsystems.com/images/products/MDM2-HDM2-Antibody-Western-Blot-NBP2-17247-img0027.jpg "Western Blot: MDM2/HDM2 Antibody [NBP2-17247]")
Reactivity:
Human, Mouse, Rat
Details:
Rabbit IgG Polyclonal
Applications:
IHC, WB
Reactivity:
Human
Assay Range:
312-20000 pg/mL
Applications:
ELISA
Reactivity:
Human, Monkey
Details:
Mouse IgG1 Monoclonal Clone #A10E11-R
Applications:
IHC, WB, ICC/IF
Reactivity:
Human
Details:
Mouse IgG1 kappa Monoclonal Clone #1A7
Applications:
IHC, WB, ELISA, Func, Mycoplasma
![Western Blot: MDM2/HDM2 Antibody (1A7) [H00004193-M01]](https://resources.rndsystems.com/images/products/MDM2-HDM2-Antibody-1A7-Western-Blot-H00004193-M01-img0018.jpg "Western Blot: MDM2/HDM2 Antibody (1A7) [H00004193-M01]")
Reactivity:
Human
Source:
E. coli
Applications:
Bioactivity
Chemical Name:
4-[[(4S,5R)-4,5-bis(4-Chlorophenyl)-4,5-dihydro-2-[4-methoxy-2-(1-methylethoxy)phenyl]-1H-imidazol-1-yl]carbonyl]-2-piperazinone
Purity:
≥97%
MDM2/HDM2 Antibody (24GB7055)
Catalog #:
NBP3-50875
Reactivity:
Human, Mouse, Rat
Details:
Mouse IgG1 kappa Monoclonal Clone #24GB7055
Applications:
WB, Flow, ICC/IF
Chemical Name:
5-[[3-Dimethylamino)propyl]amino]-3,10-dimethylpyrimido[4,5-b]quinoline-2,4(3H,10H)-dione dihydrochloride
Purity:
≥98%
Reactivity:
Human, Mouse, Rat
Details:
Rabbit IgG Polyclonal
Applications:
WB
![Western Blot: MDM2/HDM2 [p Ser166] AntibodyBSA Free [NBP3-05384]](https://resources.rndsystems.com/images/products/MDM2-HDM2-[p-Ser166]-Antibody-Western-Blot-NBP3-05384-img0002.jpg "Western Blot: MDM2/HDM2 [p Ser166] AntibodyBSA Free [NBP3-05384]")
Alternate Names:
NSC 652287
Chemical Name:
5,5'-(2,5-Furandiyl)bis-2-thiophenemethanol
Purity:
≥97%
Chemical Name:
6-Methoxy-1-(1-naphthalenyl)-9H-pyrido[3,4-b]indole
Purity:
≥98%
Chemical Name:
4-[[[(2R,3S,4R,5S)-3-(3-Chloro-2-fluorophenyl)-4-(4-chloro-2-fluorophenyl)-4-cyano-5-(2,2-dimethylpropyl)-2-pyrrolidinyl]carbonyl]amino]-3-methoxybenzoic acid
Purity:
≥98%
Reactivity:
Human, Mouse, Rat
Details:
Rabbit IgG Polyclonal
Applications:
IHC, WB
Reactivity:
Human, Mouse, Rat
Details:
Rabbit IgG Polyclonal
Applications:
IHC, WB
Reactivity:
Human, Mouse, Rat
Details:
Rabbit IgG Polyclonal
Applications:
IHC, WB
Reactivity:
Human, Mouse, Rat
Details:
Rabbit IgG Polyclonal
Applications:
IHC, WB
Reactivity:
Human, Mouse, Rat
Details:
Rabbit IgG Polyclonal
Applications:
IHC, WB
Reactivity:
Human, Mouse, Rat
Details:
Rabbit IgG Polyclonal
Applications:
IHC, WB