S100A8 Products
S100A8 (also MRP8 and calgranulin A) is a 10 kDa member of the S100 family, EF-hand superfamily of Ca-binding proteins. It is produced by neutrophils and monocytes, and forms Ca2+-dependent heterodimer/heterotetramer complexes (termed calprotectin) with S100A9. It functions both intracellularly and extracellularly, where it binds to RAGE and CD36. Human S100A8 is 93 amino acids (aa) in length. It contains two EF-hand motifs (aa 12 - 47 and 46 - 81) and one high-affinity Ca2+-binding site (aa 59 - 70). There may be one splice form that shows a 15 aa substitution for the C-terminal 14 amino acids. Although mouse S100A8 is cleaved by MMP-2 after Asn21, it is unclear if human S100A8 is susceptible. Full-length human S100A8 is 57% and 74% aa identical to mouse and canine S100A8, respectively.
459 results for "S100A8" in Products
459 results for "S100A8" in Products
S100A8 Products
S100A8 (also MRP8 and calgranulin A) is a 10 kDa member of the S100 family, EF-hand superfamily of Ca-binding proteins. It is produced by neutrophils and monocytes, and forms Ca2+-dependent heterodimer/heterotetramer complexes (termed calprotectin) with S100A9. It functions both intracellularly and extracellularly, where it binds to RAGE and CD36. Human S100A8 is 93 amino acids (aa) in length. It contains two EF-hand motifs (aa 12 - 47 and 46 - 81) and one high-affinity Ca2+-binding site (aa 59 - 70). There may be one splice form that shows a 15 aa substitution for the C-terminal 14 amino acids. Although mouse S100A8 is cleaved by MMP-2 after Asn21, it is unclear if human S100A8 is susceptible. Full-length human S100A8 is 57% and 74% aa identical to mouse and canine S100A8, respectively.
| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, Simple Western, ICC |
| Assay Range: | 31.2 - 2,000 pg/mL |
| Applications: | ELISA |
| Source: | E. coli |
| Applications: | BA |
| Reactivity: | Human |
| Details: | Sheep IgG Polyclonal |
| Applications: | WB, Simple Western, CyTOF-ready, ICC, ICFlow |
| Reactivity: | Mouse |
| Details: | Rat IgG2b Monoclonal Clone #335806 |
| Applications: | WB, ICC |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #749916 |
| Applications: | WB, IHC |
| Applications: | ELISA |
| Reactivity: | Human, Mouse |
| Details: | Rat IgG2b Lambda Monoclonal Clone #63N13G5 |
| Applications: | IHC, WB, Flow |
| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, ICC |
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #1099F |
| Applications: | IHC, Dual ISH-IHC, ICC |
| Source: | E. coli |
| Accession #: | P27005 |
| Applications: | BA |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #900027 |
| Applications: | ELISA, IHC, CyTOF-ready, ICFlow |
| Source: | E. coli |
| Accession #: | P05109 |
| Applications: | BA |
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG2b Kappa Monoclonal Clone #48M7C7 |
| Applications: | IHC, WB, ICC/IF, Flow |
![Flow Cytometry: S100A8 Antibody (48M7C7) - Azide Free [NBP2-25269]](https://resources.bio-techne.com/images/products/S100A8-A9-Antibody-48M7C7-Azide-Free-Flow-Cytometry-NBP2-25269-img0003.jpg "Flow Cytometry: S100A8 Antibody (48M7C7) - Azide Free [NBP2-25269]")
| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, ICC |
| Reactivity: | Human |
| Details: | Mouse IgG2a Monoclonal Clone #900028 |
| Applications: | ELISA, CyTOF-ready, ICFlow |
| Reactivity: | Mouse |
| Details: | Rat IgG Lambda Monoclonal Clone #63N13G5 |
| Applications: | IHC, WB, Flow |
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG2b Kappa Monoclonal Clone #48M7C7 |
| Applications: | IHC, WB, Flow |
![Flow Cytometry: S100A8 Antibody (48M7C7) [NBP2-25256]](https://resources.bio-techne.com/images/products/S100A8-A9-Antibody-48M7C7-Flow-Cytometry-NBP2-25256-img0003.jpg "Flow Cytometry: S100A8 Antibody (48M7C7) [NBP2-25256]")
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF |
![S100A8 Antibody - BSA Free Immunocytochemistry/ Immunofluorescence: S100A8 Antibody - BSA Free [NBP1-90314]](https://resources.bio-techne.com/images/products/nbp1-90314_rabbit-polyclonal-s100a8-antibody-29520251675316.jpg "Immunocytochemistry/ Immunofluorescence: S100A8 Antibody - BSA Free [NBP1-90314]")
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #900027 |
| Applications: | ICFlow |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #900027 |
| Applications: | ICFlow |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #900027 |
| Applications: | ICFlow |
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG2b Kappa Monoclonal Clone #48M7F9 |
| Applications: | IHC, WB |
![Immunohistochemistry-Paraffin: S100A8 Antibody (48M7F9) [NBP2-25257]](https://resources.bio-techne.com/images/products/S100A8-A9-Antibody-48M7F9-Immunohistochemistry-Paraffin-NBP2-25257-img0003.jpg "Immunohistochemistry-Paraffin: S100A8 Antibody (48M7F9) [NBP2-25257]")
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #749916 |
| Applications: | WB, IHC |
| Reactivity: | Human |
| Details: | Sheep IgG Polyclonal |
| Applications: | WB, CyTOF-ready, ICC, ICFlow |