ROCK1: Small Molecules and Peptides
14 results for "ROCK1 Small Molecules and Peptides" in Products
14 results for "ROCK1 Small Molecules and Peptides" in Products
ROCK1: Small Molecules and Peptides
Selective ROCK inhibitor; inhibits ROCK1 (p160 ROCK) and ROCK2; stem cell freezing (cryopreservation) media component
| Alternate Names: | y27632,Y-27632 2HCl,ROCK inhibitor,ROCK1 inhibitor |
| Chemical Name: | trans-4-[(1R)-1-Aminoethyl]-N-4-pyridinylcyclohexanecarboxamide dihydrochloride |
| Purity: | ≥98% (HPLC) |
Y-27632 synthesized to cGMP guidelines
| Chemical Name: | trans-4-[(1R)-1-Aminoethyl]-N-4-pyridinylcyclohexanecarboxamide dihydrochloride |
| Purity: | ≥99% |
Selective Rho-kinase (ROCK) inhibitor
| Chemical Name: | (S)-(+)-2-Methyl-1-[(4-methyl-5-isoquinolinyl)sulfonyl]-hexahydro-1H-1,4-diazepine dihydrochloride |
| Purity: | ≥98% (HPLC) |
Sterile-filtered 10 mM solution of Y-27632 pre-dissolved in water
| Chemical Name: | trans-4-[(1R)-1-Aminoethyl]-N-4-pyridinylcyclohexanecarboxamide dihydrochloride |
| Purity: | ≥97% (HPLC) |
ROCK inhibitor; improves the efficiency of fibroblast reprogramming and induction of iPSCs
| Chemical Name: | N-Benzyl-[2-(pyrimidin-4-yl)amino]thiazole-4-carboxamide |
| Purity: | ≥98% (HPLC) |
Inhibitor of cyclic nucleotide dependent- and Rho-kinases
| Alternate Names: | HA 1077 |
| Purity: | ≥98% (HPLC) |
Potent and selective ROCK inhibitor
| Chemical Name: | N-[3-[[2-(4-Amino-1,2,5-oxadiazol-3-yl)-1-ethyl-1H-imidazo[4,5-c]pyridin-6-yl]oxy]phenyl]-4-[2-(4-morpholinyl)ethoxy]benzamide |
| Purity: | ≥98% (HPLC) |
Selective Rho-kinase (ROCK) inhibitor. More selective analog of H 1152 dihydrochloride (Cat. No. 2414)
| Chemical Name: | (S)-(+)-4-Glycyl-2-methyl-1-[(4-methyl-5-isoquinolinyl)sulfonyl]-hexahydro-1H-1,4-diazepine dihydrochloride |
| Purity: | ≥98% (HPLC) |
Potent and highly selective ROCK inhibitor; orally active
| Alternate Names: | Azaindole-1,BAY-549 |
| Chemical Name: | 6-Chloro-N4-[3,5-difluoro-4-[(3-methyl-1H-pyrrolo[2,3-b]pyridin-4-yl)oxy]phenyl]-2,4-pyrimidinediamine |
| Purity: | ≥98% (HPLC) |
Potent and selective ROCK inhibitor; orally bioavailable and brain penetrant
| Chemical Name: | (2R)-4-(3-Fluoro-4-pyridinyl)-N-[(1R)-1-(3-methoxyphenyl)ethyl]-2-methyl-1-piperazinecarboxamide |
| Purity: | ≥98% (HPLC) |
Potent and selective ROCK inhibitor; antitumor
| Chemical Name: | N-[(3-Hydroxyphenyl)methyl]-N'-[4-(4-pyridinyl)-2-thiazolyl]urea dihydrochloride |
| Purity: | ≥98% (HPLC) |
Potent ROCK inhibitor
| Chemical Name: | 2-Fluoro-N-[[4-(1H-pyrrolo[2,3-b]pyridin-4-yl)phenyl]methyl]benzenemethanamine dihydrochloride |
| Purity: | ≥98% (HPLC) |
Potent and selective LIMK inhibitor; antitumor
| Chemical Name: | N-(2-Hydroxyethyl)-N'-[4,5-methyl-7H-pyrrolo[2,3-d]pyrimidine-4-yl)phenyl]-N-phenylurea |
| Purity: | ≥98% (HPLC) |
Potent Rho-kinase inhibitor; vasodilator
| Chemical Name: | (3S)-1-[[2-(4-Amino-1,2,5-oxadiazol-3-yl)-1-ethyl-1H-imidazo[4,5-c]pyridin-7-yl]carbonyl]-3-pyrrolidinamine dihydrochloride |
| Purity: | ≥98% (HPLC) |
