Hedgehog Signaling Inhibitors: Small Molecules and Peptides
12 results for "Hedgehog Signaling Inhibitors Small Molecules and Peptides" in Products
12 results for "Hedgehog Signaling Inhibitors Small Molecules and Peptides" in Products
Hedgehog Signaling Inhibitors: Small Molecules and Peptides
Hedgehog signaling inhibitor; dynein inhibitor
| Chemical Name: | 2-[1-(4-Chlorophenyl)cyclopropyl]-4,5-dihydro-7-iodo-5-oxopyrazolo[1,5-a]quinazoline-3-carbonitrile |
| Purity: | ≥98% (HPLC) |
Inhibitor of Hedgehog (Hh) signaling
| Chemical Name: | (2'R,3S,3'R,3'aS,6'S,6aS,6bS,7'aR,11aS,11bR)-1,2,3,3'a,4,4',5',6,6',6a,6b,7,7',7'a,8,11,11a,11b-Octadecahydro-3',6',10,11b-tetramethylspiro[9H-benzo[a]fluorene-9,2'(3'H)-furo[3,2-b]pyridin]-3-ol |
| Purity: | ≥97% (HPLC) |
Inhibitor of hedgehog (Hh) signaling; antagonizes smoothened activity
| Chemical Name: | N-[(3,5-dimethyl-1-phenyl-1H-pyrazol-4-yl)methylene]-4-(phenylmethyl)-1-piperazinamine |
| Purity: | ≥98% (HPLC) |
Inhibitor of Hedgehog (Hh) signaling. Inhibits Δ7-dehydrocholesterol reductase
| Chemical Name: | trans-N,N-bis[2-Chlorophenylmethyl]-1,4-cyclohexanedimethanamine dihydrochloride |
| Purity: | ≥98% (HPLC) |
Inhibitor of Hedgehog (Hh) signaling; inhibits cytoplasmic dynein
| Chemical Name: | Ethyl 4-(4-(diethylamino)phenyl)-2-((2,4-difluorophenyl)amino)thiazole-5-carboxylate |
| Purity: | ≥98% (HPLC) |
GLI antagonist; inhibits Hedgehog (Hh) signaling
| Chemical Name: | 2,2'-[[Dihydro-2-(4-pyridinyl)-1,3(2H,4H)-pyrimidinediyl]bis(methylene)]bis[N,N-dimethylbenzenamine |
| Purity: | ≥98% (HPLC) |
Potent hedgehog pathway inhibitor
| Chemical Name: | 2-Chloro-N-[4-chloro-3-(2-pyridinyl)phenyl]-4-(methylsulfonyl)benzamide |
| Purity: | ≥98% (HPLC) |
BET bromodomain Degrader (PROTAC®); also potent Hedgehog pathway inhibitor
| Chemical Name: | 2-Methoxyethyl 4-(3-((1-(6-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)hexyl)-1H-1,2,3-triazol-4-yl)methoxy)phenyl)-7-(2-methoxyphenyl)-2-methyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylate |
| Purity: | ≥98% (HPLC) |
Potent Smo antagonist
| Chemical Name: | N,N'-1,4-Phenylenebis[2,5-dichlorobenzamide] |
| Purity: | ≥98% (HPLC) |
Potent Smoothened receptor antagonist
| Chemical Name: | rel-N-[6-[(2R,6S)-2,6-Dimethyl-4-morpholinyl]-3-pyridinyl]-2-methyl-4'-(trifluoromethoxy)[1,1'-biphenyl]-3-carboxamide |
| Purity: | ≥98% (HPLC) |
Potent Smo antagonist
| Alternate Names: | glasdegib,PF-913 |
| Chemical Name: | 1-((2R,4R)-2-(1H-Benzimidazol-2-yl)-1-methylpiperidin-4-yl)-3-(4-cyanophenyl)urea maleate salt |
| Purity: | ≥98% (HPLC) |
High affinity and selective Smoothened (Smo) receptor antagonist
| Chemical Name: | 1-[4-(5'-Chloro-3,5-dimethyl[2,4'-bipyridin]-2'-yl-1-piperazinyl]-3-(methylsulfonyl)-1-propanone hydrochloride |
| Purity: | ≥98% (HPLC) |
