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gp130 Products
Gp130, the common signal transducing receptor component shared by the functional receptor complexes of the IL-6 family of cytokines, belongs to the classI cytokine receptor family. Binding of IL-6 or IL-11 to either the membrane-anchored or soluble IL-6 R or IL-11 R, respectively, initiates the association of IL-6 R (IL-11 R) with gp130. The complex then undergoes homodimerization and signal transduction. For other IL-6 family cytokines, such as LIF and OSM, signal transduction is similarly triggered by the heterodimerization of gp130 with LIFR or OSM R.
61 results for "gp130" in Products
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gp130 Products
Gp130, the common signal transducing receptor component shared by the functional receptor complexes of the IL-6 family of cytokines, belongs to the classI cytokine receptor family. Binding of IL-6 or IL-11 to either the membrane-anchored or soluble IL-6 R or IL-11 R, respectively, initiates the association of IL-6 R (IL-11 R) with gp130. The complex then undergoes homodimerization and signal transduction. For other IL-6 family cytokines, such as LIF and OSM, signal transduction is similarly triggered by the heterodimerization of gp130 with LIFR or OSM R.
61 results for "gp130" in Products
| Sensitivity : | 0.05 ng/mL (Cell Culture Supernates) 0.08 ng/mL (Serum, EDTA Plasma, Heparin Plasma, Citrate Plasma) |
| Assay Range : | 0.125 - 8 ng/mL (Cell Culture Supernates) 0.25 - 16 ng/mL (Serum, EDTA Plasma, Heparin Plasma, Citrate Plasma) |
| Applications : | ELISA |
| Source : | NS0 |
| Accession # : | EDM10349 |
| Applications : | Bioactivity |
| Source : | NS0 |
| Accession # : | P40189 |
| Applications : | Bioactivity |
Simple Plex Human GP130 assay kit for use on Ella instrument. Contains cartridge, sample diluent SD13, and wash buffer.
Create your custom Simple Plex cartridge for up to 8 targets. Choose from more than 250 targets across multiple species.
| Source : | Sf 21 (baculovirus) |
| Accession # : | P40189 |
| Applications : | Bioactivity |
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | Block/Neutralize, Western Blot |
| Assay Range : | 125 - 8,000 pg/mL |
| Applications : | ELISA |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #29104 |
| Applications : | ELISA |
| Source : | NS0 |
| Accession # : | Q6PDI9 |
| Applications : | Bioactivity |
| Clonality : | Monoclonal |
| Host : | Rat IgG2a Clone #125623 |
| Applications : | CyTOF-ready, Flow Cytometry, Immunocytochemistry/Immunofluorescence |
gp130 agonist; brain penetrant and neuroprotectant
| Chemical Name : | N-(4-Fluorophenyl)-4-phenyl-2-thiazolamine |
| Purity : | ≥98% (HPLC) |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #28126 |
| Applications : | Flow Cytometry |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #28126 |
| Applications : | Block/Neutralize, CyTOF-ready, Flow Cytometry |
| Clonality : | Monoclonal |
| Host : | Rat IgG1 Clone #125605 |
| Applications : | Block/Neutralize, ELISA Capture |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #28105 |
| Applications : | Block/Neutralize, ELISA Capture, Immunohistochemistry |
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | CyTOF-ready, Flow Cytometry, Western Blot |
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | ELISA Detection, Flow Cytometry, Western Blot |
Biotinylated
| Source : | CHO |
| Accession # : | AAA59155.1 |
| Applications : | Bioactivity |
| Clonality : | Monoclonal |
| Host : | Rat IgG2a Clone #125623 |
| Applications : | Flow Cytometry |
Biotinylated
| Source : | HEK293 |
| Accession # : | AAA59155.1 |
| Applications : | Bioactivity |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #28126 |
| Applications : | Flow Cytometry |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #745314 |
| Applications : | CyTOF-ready, Flow Cytometry, Western Blot |
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | ELISA Detection, Western Blot |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #28126 |
| Applications : | Flow Cytometry |
