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gp130: Antibodies

Gp130, the common signal transducing receptor component shared by the functional receptor complexes of the IL-6 family of cytokines, belongs to the classI cytokine receptor family. Binding of IL-6 or IL-11 to either the membrane-anchored or soluble IL-6 R or IL-11 R, respectively, initiates the association of IL-6 R (IL-11 R) with gp130. The complex then undergoes homodimerization and signal transduction. For other IL-6 family cytokines, such as LIF and OSM, signal transduction is similarly triggered by the heterodimerization of gp130 with LIFR or OSM R.

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168 results for "gp130 Primary Antibodies" in Products

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gp130: Antibodies

Gp130, the common signal transducing receptor component shared by the functional receptor complexes of the IL-6 family of cytokines, belongs to the classI cytokine receptor family. Binding of IL-6 or IL-11 to either the membrane-anchored or soluble IL-6 R or IL-11 R, respectively, initiates the association of IL-6 R (IL-11 R) with gp130. The complex then undergoes homodimerization and signal transduction. For other IL-6 family cytokines, such as LIF and OSM, signal transduction is similarly triggered by the heterodimerization of gp130 with LIFR or OSM R.

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168 results for "gp130 Primary Antibodies" in Products

Flow, CyTOF-ready, ICC
Flow, CyTOF-ready, Neut
WB, Flow, CyTOF-ready
WB, Flow, CyTOF-ready
Flow
Catalog #: BAF468
WB, Flow
Catalog #: FAB5029G
Flow
Catalog #: FAB228S
Flow
Flow, ICC
WB, Neut
WB
IHC, WB, ICC/IF
Flow
Catalog #: MAB468
WB
Catalog #: FAB4681S
Flow
Catalog #: FAB5029V
Flow
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