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gp130: Antibodies

Gp130, the common signal transducing receptor component shared by the functional receptor complexes of the IL-6 family of cytokines, belongs to the classI cytokine receptor family. Binding of IL-6 or IL-11 to either the membrane-anchored or soluble IL-6 R or IL-11 R, respectively, initiates the association of IL-6 R (IL-11 R) with gp130. The complex then undergoes homodimerization and signal transduction. For other IL-6 family cytokines, such as LIF and OSM, signal transduction is similarly triggered by the heterodimerization of gp130 with LIFR or OSM R.

40 results for "gp130 Primary Antibodies" in Products

gp130: Antibodies

Gp130, the common signal transducing receptor component shared by the functional receptor complexes of the IL-6 family of cytokines, belongs to the classI cytokine receptor family. Binding of IL-6 or IL-11 to either the membrane-anchored or soluble IL-6 R or IL-11 R, respectively, initiates the association of IL-6 R (IL-11 R) with gp130. The complex then undergoes homodimerization and signal transduction. For other IL-6 family cytokines, such as LIF and OSM, signal transduction is similarly triggered by the heterodimerization of gp130 with LIFR or OSM R.

40 results for "gp130 Primary Antibodies" in Products

Catalog #: BAF468
WB, Flow
WB, Flow, CyTOF-ready
Flow, CyTOF-ready, Neut
Catalog #: MAB468
WB
WB, Neut
Catalog #: FAB4681R
Flow
WB
Catalog #: FAB4681G
Flow
Catalog #: FAB228R
Flow
Catalog #: FAB228S
Flow
Catalog #: FAB228T
Flow
Catalog #: FAB4681S
Flow
Catalog #: FAB5029T
Flow
Flow, CyTOF-ready, ICC
Catalog #: FAB4681N
Flow
Catalog #: FAB4681T
Flow
Catalog #: FAB4681U
Flow
Catalog #: FAB4681V
Flow
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