15 results for "Class I Histone Deacetylases Inhibitors Small Molecules and Peptides" in Products
Class I Histone Deacetylases Inhibitors: Small Molecules and Peptides
HDAC classification
| Superfamily | Family | Class | Subclass | Protein (human) |
|---|---|---|---|---|
| Arginase/deacetylase superfamily | Histone deacetylase family | Class I | HDAC1, HDAC2, HDAC3, HDAC8 | |
| Class II | Class IIa | HDAC4, HDAC5, HDAC7, HDAC9 | ||
| ClassIIb | HDAC6, HDAC10 | |||
| Class IV | HDAC11 | |||
| Deoxyhypusine synthase like NAD/FAD-binding domain superfamily | Sir2 regulator family | Class III | I | SIRT1, SIRT2, SIRT3 |
| II | SIRT4 | |||
| III | SIRT5 | |||
| IV | SIRT6, SIRT7 |
Potent and selective class I histone deacetylase inhibitor; antitumor
| Alternate Names: | Depsipeptide,FR 901228,Romidepsin |
| Chemical Name: | Cyclo[(2Z)-2-amino-2-butenoyl-L-valyl-(3S,4E)-3-hydroxy-7-mercapto-4-heptenoyl-D-valyl-D-cysteinyl], cyclic (3-5) disulfide |
| Purity: | ≥98% (HPLC) |
Histone deacetylase inhibitor
| Alternate Names: | VPA,Sodium Valproate |
| Chemical Name: | Sodium 2-propylpentanoate |
Histone deacetylase inhibitor
| Alternate Names: | 4-PB,Sodium phenylbutyrate |
| Chemical Name: | 4-Phenylbutyric acid, sodium salt |
| Purity: | ≥98% (HPLC) |
Potent histone deacetylase inhibitor
| Chemical Name: | (2E,4E,6R)-7-(4-(Dimethylamino)phenyl)-N-hydroxy-4,6-dimethyl-7-oxo-2,4-heptadienamide |
| Purity: | ≥95% (HPLC) |
Histone deacetylase inhibitor
| Chemical Name: | Butanoic acid sodium salt |
Histone deacetylase inhibitor
| Alternate Names: | ITF 2357 |
| Chemical Name: | [6-[(Diethylamino)methyl]-2-naphthalenyl]methyl-N-[4-[(hydroxyamino)carbonyl]phenyl]carbamate hydrochloride |
| Purity: | ≥98% (HPLC) |
Class I and II HDAC inhibitor
| Alternate Names: | Vorinostat |
| Chemical Name: | N-Hydroxy-N'-phenyloctanediamide |
| Purity: | ≥98% (HPLC) |
Pan-histone deacetylase inhibitor
| Chemical Name: | (2E)-N-Hydroxy-3-[4-[[[2-(2-methyl-1H-indol-3-yl)ethyl]amino]methyl]phenyl]-2-propenamide |
| Purity: | ≥98% (HPLC) |
Histone deacetylase inhibitor
| Chemical Name: | 3,4-Dichloro-N-(1-methylbutyl)benzamide |
| Purity: | ≥98% (HPLC) |
HDAC (Class I) inhibitor
| Alternate Names: | entinostat,SNDX 275 |
| Chemical Name: | (Pyridin-3-yl)methyl 4-(2-aminophenylcarbamoyl)benzylcarbamate |
| Purity: | ≥98% (HPLC) |
Potent class I and IIb HDAC inhibitor
| Chemical Name: | 5-[(4-[1,1'-Biphenyl]-4-yl-1,6-dihydro-6-oxo-2-pyrimidinyl)thio]-N-hydroxypentanamide |
| Purity: | ≥98% (HPLC) |
Dual histone deacetylase (HDAC) 6/8 inhibitor
| Chemical Name: | N1-Hydroxy-N3-(2-phenylethyl)-1,3-benzenedicarboxamide |
| Purity: | ≥98% (HPLC) |
Potent and selective HDAC8 inhibitor
| Chemical Name: | N-Hydroxy-1-[(4-methoxyphenyl)methyl]-1H-indole-6-carboxamide |
| Purity: | ≥98% (HPLC) |
Potent and selective HDAC3 inhibitor
| Chemical Name: | (2E)-N-(2-Amino-4-fluorophenyl)-3-[1-(3-phenyl-2-propen-1-yl)-1H-pyrazol-4-yl]-2-propenamide |
| Purity: | ≥98% (HPLC) |
Selective HDAC3 inhibitor; also myelination inducer
| Chemical Name: | N-(2-Aminophenyl)-5-[(phenylmethyl)amino]-2-pyrazinecarboxamide dihydrochloride |
| Purity: | ≥98% (HPLC) |
