PDGF R beta Products
PDGF R beta is a transmembrane receptor tyrosine kinase (RTK) that primarily binds to the PDGF-BB isoform of the growth factor. Ligand binding induces receptor homodimerization or heterodimerization with PDGF R alpha followed by autophosphorylation and signal transduction. PDGF receptor signaling is attenuated by SHP-2 phosphatase activity and by receptor endocytosis and lysosomal degradation. The expression of the alpha and beta receptors is independently regulated in various cell types. A soluble splice variant of PDGF R beta binds PDGF with high affinity and functions as a potent PDGF antagonist.
54 results for "PDGF R beta" in Products
Search
Application
Conjugates
Clonality
Host Species
Isotype
Clone
Low Endotoxin
Sample Size
Citations
Reviews
PDGF R beta Products
PDGF R beta is a transmembrane receptor tyrosine kinase (RTK) that primarily binds to the PDGF-BB isoform of the growth factor. Ligand binding induces receptor homodimerization or heterodimerization with PDGF R alpha followed by autophosphorylation and signal transduction. PDGF receptor signaling is attenuated by SHP-2 phosphatase activity and by receptor endocytosis and lysosomal degradation. The expression of the alpha and beta receptors is independently regulated in various cell types. A soluble splice variant of PDGF R beta binds PDGF with high affinity and functions as a potent PDGF antagonist.
54 results for "PDGF R beta" in Products
Source : | NS0 |
Accession # : | P09619 |
Applications : | Bioactivity |
Source : | NS0 |
Accession # : | P05622 |
Applications : | Bioactivity |
Biotinylated
Source : | CHO |
Accession # : | AAA36427.1 |
Applications : | Bioactivity |
Applications : | ELISA |
Assay Range : | 250 - 16,000 pg/mL |
Applications : | ELISA |
Source : | NS0 |
Accession # : | Q05030.2 |
Applications : | Bioactivity |
Source : | HEK293 |
Accession # : | AAA36427.1 |
Applications : | Bioactivity |
Source : | NS0 |
Accession # : | P05622 |
Applications : | Bioactivity |
Assay Range : | 125 - 8,000 pg/mL |
Applications : | ELISA |
Assay Range : | 15.6 - 1,000 pg/mL |
Applications : | ELISA |
Clonality : | Monoclonal |
Host : | Mouse IgG1 Clone #PR7212 |
Applications : | Flow Cytometry |
Clonality : | Monoclonal |
Host : | Mouse IgG1 Clone #PR7212 |
Applications : | Flow Cytometry |
Clonality : | Monoclonal |
Host : | Mouse IgG1 Clone #PR7212 |
Applications : | Flow Cytometry |
Clonality : | Monoclonal |
Host : | Mouse IgG1 Clone #PR7212 |
Applications : | Flow Cytometry |
Clonality : | Monoclonal |
Host : | Mouse IgG1 Clone #PR7212 |
Applications : | Flow Cytometry |
Clonality : | Monoclonal |
Host : | Mouse IgG1 Clone #PR7212 |
Applications : | Flow Cytometry |
Clonality : | Polyclonal |
Host : | Goat IgG |
Applications : | Immunohistochemistry, Western Blot |
Clonality : | Polyclonal |
Host : | Goat IgG |
Applications : | Block/Neutralize, CyTOF-ready, Flow Cytometry, Immunohistochemistry, Western Blot |
Clonality : | Monoclonal |
Host : | Mouse IgG1 Clone #PR7212 |
Applications : | Flow Cytometry, Immunohistochemistry, Immunoprecipitation, Western Blot |
Clonality : | Monoclonal |
Host : | Mouse IgG1 Clone #PR7212 |
Applications : | Flow Cytometry |
Clonality : | Polyclonal |
Host : | Goat IgG |
Applications : | Immunohistochemistry, Western Blot |
Recombinant Monoclonal Antibody.
Clonality : | Monoclonal |
Host : | Rabbit IgG Clone #1210B |
Applications : | Immunocytochemistry/Immunofluorescence, Simple Western, Western Blot |