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PDGF R beta Products
PDGF R beta is a transmembrane receptor tyrosine kinase (RTK) that primarily binds to the PDGF-BB isoform of the growth factor. Ligand binding induces receptor homodimerization or heterodimerization with PDGF R alpha followed by autophosphorylation and signal transduction. PDGF receptor signaling is attenuated by SHP-2 phosphatase activity and by receptor endocytosis and lysosomal degradation. The expression of the alpha and beta receptors is independently regulated in various cell types. A soluble splice variant of PDGF R beta binds PDGF with high affinity and functions as a potent PDGF antagonist.
54 results for "PDGF R beta" in Products
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PDGF R beta Products
PDGF R beta is a transmembrane receptor tyrosine kinase (RTK) that primarily binds to the PDGF-BB isoform of the growth factor. Ligand binding induces receptor homodimerization or heterodimerization with PDGF R alpha followed by autophosphorylation and signal transduction. PDGF receptor signaling is attenuated by SHP-2 phosphatase activity and by receptor endocytosis and lysosomal degradation. The expression of the alpha and beta receptors is independently regulated in various cell types. A soluble splice variant of PDGF R beta binds PDGF with high affinity and functions as a potent PDGF antagonist.
54 results for "PDGF R beta" in Products
| Source : | NS0 |
| Accession # : | P09619 |
| Applications : | Bioactivity |
| Source : | NS0 |
| Accession # : | P05622 |
| Applications : | Bioactivity |
Biotinylated
| Source : | CHO |
| Accession # : | AAA36427.1 |
| Applications : | Bioactivity |
| Applications : | ELISA |
| Assay Range : | 250 - 16,000 pg/mL |
| Applications : | ELISA |
| Source : | NS0 |
| Accession # : | Q05030.2 |
| Applications : | Bioactivity |
| Source : | HEK293 |
| Accession # : | AAA36427.1 |
| Applications : | Bioactivity |
| Source : | NS0 |
| Accession # : | P05622 |
| Applications : | Bioactivity |
| Assay Range : | 125 - 8,000 pg/mL |
| Applications : | ELISA |
| Assay Range : | 15.6 - 1,000 pg/mL |
| Applications : | ELISA |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #PR7212 |
| Applications : | Flow Cytometry |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #PR7212 |
| Applications : | Flow Cytometry |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #PR7212 |
| Applications : | Flow Cytometry |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #PR7212 |
| Applications : | Flow Cytometry |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #PR7212 |
| Applications : | Flow Cytometry |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #PR7212 |
| Applications : | Flow Cytometry |
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | Immunohistochemistry, Western Blot |
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | Block/Neutralize, CyTOF-ready, Flow Cytometry, Immunohistochemistry, Western Blot |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #PR7212 |
| Applications : | Flow Cytometry, Immunohistochemistry, Immunoprecipitation, Western Blot |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #PR7212 |
| Applications : | Flow Cytometry |
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | Immunohistochemistry, Western Blot |
Recombinant Monoclonal Antibody.
| Clonality : | Monoclonal |
| Host : | Rabbit IgG Clone #1210B |
| Applications : | Immunocytochemistry/Immunofluorescence, Simple Western, Western Blot |
