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IL-18/IL-1F4 Products

IL-18 (Interleukin-18) is secreted by macrophages, dendritic cells, and epithelial cells. Circulating mature IL-18 is sequestered by soluble IL-18 binding proteins (IL-18 BP) that inhibit IL-18 bioactivity. IL-18 signals through a receptor complex that contains IL-18 R alpha IL-18 R beta. It synergizes with other cytokines to activate NK, Th1, and Th17 cells and to increase the production of IFN-gamma. It can also promote Th2 cytokine release which reduces the effectiveness of antiviral responses. Increased levels of active IL-18 contribute to the severity of autoimmunity and hypertension, while deficiency of IL-18 results in symptoms of metabolic syndrome. In cancer, IL-18 stimulates Th1 and NK cells to target tumor cells, but it can also promote angiogenesis, metastasis, and tumor cell immune evasion.

69 results for "IL-18/IL-1F4" in Products

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IL-18/IL-1F4 Products

IL-18 (Interleukin-18) is secreted by macrophages, dendritic cells, and epithelial cells. Circulating mature IL-18 is sequestered by soluble IL-18 binding proteins (IL-18 BP) that inhibit IL-18 bioactivity. IL-18 signals through a receptor complex that contains IL-18 R alpha IL-18 R beta. It synergizes with other cytokines to activate NK, Th1, and Th17 cells and to increase the production of IFN-gamma. It can also promote Th2 cytokine release which reduces the effectiveness of antiviral responses. Increased levels of active IL-18 contribute to the severity of autoimmunity and hypertension, while deficiency of IL-18 results in symptoms of metabolic syndrome. In cancer, IL-18 stimulates Th1 and NK cells to target tumor cells, but it can also promote angiogenesis, metastasis, and tumor cell immune evasion.

69 results for "IL-18/IL-1F4" in Products

Contains 4 membranes - each spotted in duplicate with 36 different cytokine antibodies

Simple Plex automated IL-6 ELISA kit for use with human CCS/Plasma/Serum/CSF/BALF. Includes wash buffer and sample

BA

A New rh IL-18 is Now Available! Competitively priced; Higher purity; Lower endotoxin; Manufactured in-house!

ELISA
IP, Neut
ELISA

Recombinant Monoclonal Antibody.

ELISA

Human IL-18/IL-1F4 Quantikine ELISA Kit is now available!

BA

A New rh IL-18 is Available! Competitively priced; Higher purity; Lower endotoxin specifications; Made in-house!

Catalog #: DY10320
ELISA
BA

A New rm IL-18 is Now Available! Competitively priced; Enhanced stability; Lower endotoxin specification; Made in-house!

WB, ICC
ICFlow
Catalog #: 894960

Control for use with Human IL-18/IL-1F4 Simple Plex Cartridge Kit

WB, Simple Western, ELISA, ICC, KO, Neut
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