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IL-18/IL-1F4 Products
IL-18 (Interleukin-18) is secreted by macrophages, dendritic cells, and epithelial cells. Circulating mature IL-18 is sequestered by soluble IL-18 binding proteins (IL-18 BP) that inhibit IL-18 bioactivity. IL-18 signals through a receptor complex that contains IL-18 R alpha IL-18 R beta. It synergizes with other cytokines to activate NK, Th1, and Th17 cells and to increase the production of IFN-gamma. It can also promote Th2 cytokine release which reduces the effectiveness of antiviral responses. Increased levels of active IL-18 contribute to the severity of autoimmunity and hypertension, while deficiency of IL-18 results in symptoms of metabolic syndrome. In cancer, IL-18 stimulates Th1 and NK cells to target tumor cells, but it can also promote angiogenesis, metastasis, and tumor cell immune evasion.
72 results for "IL-18/IL-1F4" in Products
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IL-18/IL-1F4 Products
IL-18 (Interleukin-18) is secreted by macrophages, dendritic cells, and epithelial cells. Circulating mature IL-18 is sequestered by soluble IL-18 binding proteins (IL-18 BP) that inhibit IL-18 bioactivity. IL-18 signals through a receptor complex that contains IL-18 R alpha IL-18 R beta. It synergizes with other cytokines to activate NK, Th1, and Th17 cells and to increase the production of IFN-gamma. It can also promote Th2 cytokine release which reduces the effectiveness of antiviral responses. Increased levels of active IL-18 contribute to the severity of autoimmunity and hypertension, while deficiency of IL-18 results in symptoms of metabolic syndrome. In cancer, IL-18 stimulates Th1 and NK cells to target tumor cells, but it can also promote angiogenesis, metastasis, and tumor cell immune evasion.
72 results for "IL-18/IL-1F4" in Products
| Sensitivity : | 5.15 pg/mL |
| Assay Range : | 15.6 - 1,000 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma, Saliva, Urine) |
| Applications : | ELISA |
Simple Plex Human IL-18/IL-1F4 assay kit for use on Ella instrument. Contains cartridge, sample diluent SD13, and wash buffer.
Create your custom Simple Plex cartridge for up to 8 targets. Choose from more than 250 targets across multiple species.
| Assay Range : | 11.7 - 750 pg/mL |
| Applications : | ELISA |
Human IL-18/IL-1F4 Quantikine ELISA Kit is now available!
| Sensitivity : | 12.5 pg/mL |
| Assay Range : | 25.6 - 1,000 pg/mL |
| Applications : | ELISA |
Contains 4 membranes - each spotted in duplicate with 36 different cytokine antibodies
| Sensitivity : | 25 pg/mL |
| Assay Range : | 25.6 - 1,000 pg/mL |
| Applications : | ELISA |
| Source : | E. coli |
| Accession # : | Q14116 |
| Applications : | Bioactivity |
Design and order Simple Plex cartridges tailor made to meet your needs with customizable Simple Plex Assay panels for the Ella platform.
| Assay Range : | 46.9 - 3,000 pg/mL |
| Applications : | ELISA |
| Source : | E. coli |
| Accession # : | P70380 |
| Applications : | Bioactivity |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #125-2H |
| Applications : | Block/Neutralize, ELISA Capture, Immunoprecipitation |
Luminex High Performance Assays go through rigorous development, validation, and quality control testing to ensure you are getting the best performance out of your multiplex assay. Panels are customizable so you can order a selection of the analytes or the entire panel.
| Assay Range : | 62.5 - 4,000 pg/mL |
| Applications : | ELISA |
| Clonality : | Monoclonal |
| Host : | Rat IgG2a Clone #159-12B |
| Applications : | ELISA Detection |
| Source : | E. coli |
| Accession # : | P97636.1 |
| Applications : | Bioactivity |
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | Block/Neutralize, ELISA, Immunocytochemistry/Immunofluorescence, Knockout Validated, Simple Western, Western Blot |
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | Block/Neutralize, Western Blot |
| Clonality : | Monoclonal |
| Host : | Rat IgG2a Clone #74 |
| Applications : | ELISA Capture, Immunoprecipitation |
| Source : | E. coli |
| Accession # : | O19073 |
| Applications : | Bioactivity |
A New rh IL-18 is Now Available! Competitively priced; Higher purity; Lower endotoxin; Manufactured in-house!
| Source : | E. coli |
| Accession # : | AAK13416 |
| Applications : | Bioactivity |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #74801 |
| Applications : | CyTOF-ready, Flow Cytometry, Knockout Validated, Western Blot |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #923503 |
| Applications : | Immunohistochemistry |
