HVEM/TNFRSF14 Products
HVEM/TNFRSF14 (herpesvirus entry mediator) is a transmembrane protein that is most highly expressed on naïve, memory, and regulatory T cells but declines during T cell activation. It is present at low levels on most resting leukocytes. HVEM is a receptor for BTLA, CD160, and LIGHT.
A cis interaction between HVEM and BTLA promotes cell survival, while trans interaction promotes a state of lymphocyte inactivity. LIGHT is expressed following T cell activation and competes with BTLA for HVEM binding, leading to a proinflammatory response. The herpesvirus envelope glycoprotein gD, which binds HVEM to initiate membrane fusion, can antagonize both BTLA and LIGHT binding. Human, but not mouse, HVEM can also bind lymphotoxin-alpha.
Products:
305 results for "HVEM/TNFRSF14" in Products
305 results for "HVEM/TNFRSF14" in Products
HVEM/TNFRSF14 Products
HVEM/TNFRSF14 (herpesvirus entry mediator) is a transmembrane protein that is most highly expressed on naïve, memory, and regulatory T cells but declines during T cell activation. It is present at low levels on most resting leukocytes. HVEM is a receptor for BTLA, CD160, and LIGHT.
A cis interaction between HVEM and BTLA promotes cell survival, while trans interaction promotes a state of lymphocyte inactivity. LIGHT is expressed following T cell activation and competes with BTLA for HVEM binding, leading to a proinflammatory response. The herpesvirus envelope glycoprotein gD, which binds HVEM to initiate membrane fusion, can antagonize both BTLA and LIGHT binding. Human, but not mouse, HVEM can also bind lymphotoxin-alpha.
Products:
| Applications: | Ctrl, Simple Plex |
| Applications: | Simple Plex |
Create your custom Simple Plex cartridge for up to 8 targets. Choose from more than 250 targets across multiple species.
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #94801 |
| Applications: | WB, Flow, CyTOF-ready |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IHC |
| Source: | NS0 |
| Accession #: | Q92956.3 |
| Applications: | BA |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #94801 |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #2742B |
| Applications: | Flow, Neut |
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #2742C |
| Applications: | IHC |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #94804 |
| Applications: | IHC |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #94804 |
| Applications: | IHC |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #94801 |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IHC |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #94801 |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #94801 |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #2742B |
| Applications: | Flow |
| Reactivity: | Mouse |
| Details: | Rabbit IgG Monoclonal Clone #2024B |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Rabbit Monoclonal Clone #BLR062G |
| Applications: | IHC, WB, ICC/IF |
| Source: | CHO |
| Accession #: | NP_849262 |
| Applications: | Bind |
| Source: | CHO |
| Accession #: | Q92956.3 |
| Applications: | BA |
| Reactivity: | Mouse |
| Details: | Rabbit IgG Monoclonal Clone #2024B |
| Applications: | Flow |
| Reactivity: | Mouse |
| Details: | Rabbit IgG Monoclonal Clone #2024B |
| Applications: | Flow |