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HVEM/TNFRSF14 Products
HVEM/TNFRSF14 (herpesvirus entry mediator) is a transmembrane protein that is most highly expressed on naïve, memory, and regulatory T cells but declines during T cell activation. It is present at low levels on most resting leukocytes. HVEM is a receptor for BTLA, CD160, and LIGHT. A cis interaction between HVEM and BTLA promotes cell survival, while trans interaction promotes a state of lymphocyte inactivity. LIGHT is expressed following T cell activation and competes with BTLA for HVEM binding, leading to a proinflammatory response. The herpesvirus envelope glycoprotein gD, which binds HVEM to initiate membrane fusion, can antagonize both BTLA and LIGHT binding. Human, but not mouse, HVEM can also bind lymphotoxin-alpha.
48 results for "HVEM/TNFRSF14" in Products
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HVEM/TNFRSF14 Products
HVEM/TNFRSF14 (herpesvirus entry mediator) is a transmembrane protein that is most highly expressed on naïve, memory, and regulatory T cells but declines during T cell activation. It is present at low levels on most resting leukocytes. HVEM is a receptor for BTLA, CD160, and LIGHT. A cis interaction between HVEM and BTLA promotes cell survival, while trans interaction promotes a state of lymphocyte inactivity. LIGHT is expressed following T cell activation and competes with BTLA for HVEM binding, leading to a proinflammatory response. The herpesvirus envelope glycoprotein gD, which binds HVEM to initiate membrane fusion, can antagonize both BTLA and LIGHT binding. Human, but not mouse, HVEM can also bind lymphotoxin-alpha.
48 results for "HVEM/TNFRSF14" in Products
Simple Plex Human HVEM/TNFRSF14 assay kit for use on Ella instrument. Contains cartridge, sample diluent SD13, and wash buffer.
Create your custom Simple Plex cartridge for up to 8 targets. Choose from more than 250 targets across multiple species.
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #94801 |
| Applications : | CyTOF-ready, ELISA Capture, Flow Cytometry, Western Blot |
Recombinant Monoclonal Antibody.
| Clonality : | Monoclonal |
| Host : | Rabbit IgG Clone #2024B |
| Applications : | Flow Cytometry |
His-tag
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | Immunohistochemistry, Western Blot |
| Source : | CHO |
| Accession # : | NP_849262 |
| Applications : | Binding Activity |
Recombinant Monoclonal Antibody.
| Clonality : | Monoclonal |
| Host : | Rabbit IgG Clone #2742B |
| Applications : | Block/Neutralize, Flow Cytometry |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #94801 |
| Applications : | Flow Cytometry |
Recombinant Monoclonal Antibody.
| Clonality : | Monoclonal |
| Host : | Rabbit IgG Clone #2742C |
| Applications : | Immunohistochemistry |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #94804 |
| Applications : | Immunohistochemistry |
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | ELISA Detection, Western Blot |
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | Western Blot |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #94801 |
| Applications : | Flow Cytometry |
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | Western Blot |
Recombinant Monoclonal Antibody.
| Clonality : | Monoclonal |
| Host : | Rabbit IgG Clone #2024B |
| Applications : | Flow Cytometry |
| Source : | HEK293 |
| Accession # : | Q92956.3 |
| Source : | HEK293 |
| Accession # : | Q92956.3 |
| Applications : | Bioactivity |
| Assay Range : | 15.6 - 1,000 pg/mL |
| Applications : | ELISA |
| Source : | HEK293 |
| Accession # : | XP_005545061 |
| Applications : | Bioactivity |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #94801 |
| Applications : | Flow Cytometry |
Recombinant Monoclonal Antibody.
| Clonality : | Monoclonal |
| Host : | Rabbit IgG Clone #2742B |
| Applications : | Flow Cytometry |
Recombinant Monoclonal Antibody.
| Clonality : | Monoclonal |
| Host : | Rabbit IgG Clone #2024B |
| Applications : | Flow Cytometry |
Recombinant Monoclonal Antibody.
| Clonality : | Monoclonal |
| Host : | Rabbit IgG Clone #2024B |
| Applications : | Flow Cytometry |
