
HVEM/TNFRSF14 Products
HVEM/TNFRSF14 (herpesvirus entry mediator) is a transmembrane protein that is most highly expressed on naïve, memory, and regulatory T cells but declines during T cell activation. It is present at low levels on most resting leukocytes. HVEM is a receptor for BTLA, CD160, and LIGHT. A cis interaction between HVEM and BTLA promotes cell survival, while trans interaction promotes a state of lymphocyte inactivity. LIGHT is expressed following T cell activation and competes with BTLA for HVEM binding, leading to a proinflammatory response. The herpesvirus envelope glycoprotein gD, which binds HVEM to initiate membrane fusion, can antagonize both BTLA and LIGHT binding. Human, but not mouse, HVEM can also bind lymphotoxin-alpha.
48 results for "HVEM/TNFRSF14" in Products
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HVEM/TNFRSF14 Products
HVEM/TNFRSF14 (herpesvirus entry mediator) is a transmembrane protein that is most highly expressed on naïve, memory, and regulatory T cells but declines during T cell activation. It is present at low levels on most resting leukocytes. HVEM is a receptor for BTLA, CD160, and LIGHT. A cis interaction between HVEM and BTLA promotes cell survival, while trans interaction promotes a state of lymphocyte inactivity. LIGHT is expressed following T cell activation and competes with BTLA for HVEM binding, leading to a proinflammatory response. The herpesvirus envelope glycoprotein gD, which binds HVEM to initiate membrane fusion, can antagonize both BTLA and LIGHT binding. Human, but not mouse, HVEM can also bind lymphotoxin-alpha.
48 results for "HVEM/TNFRSF14" in Products
Contains 4 membranes-each spotted in duplicate with 41 different proteins and 4 serine or tyrosine phosphorylation sites antibodies
Design and order Simple Plex cartridges tailor made to meet your needs with customizable Simple Plex Assay panels for the Ella platform.
Luminex High Performance Assays go through rigorous development, validation, and quality control testing to ensure you are getting the best performance out of your multiplex assay. Panels are customizable so you can order a selection of the analytes or the entire panel.
Clonality : | Monoclonal |
Host : | Mouse IgG1 Clone #94801 |
Applications : | Flow Cytometry |
Assay Range : | 15.6 - 1,000 pg/mL |
Applications : | ELISA |
Recombinant Monoclonal Antibody.
Clonality : | Monoclonal |
Host : | Rabbit IgG Clone #2024B |
Applications : | Flow Cytometry |
Clonality : | Monoclonal |
Host : | Mouse IgG1 Clone #94801 |
Applications : | Flow Cytometry |
Recombinant Monoclonal Antibody.
Clonality : | Monoclonal |
Host : | Rabbit IgG Clone #2742C |
Applications : | Immunohistochemistry |
Clonality : | Monoclonal |
Host : | Mouse IgG1 Clone #94801 |
Applications : | Flow Cytometry |
Clonality : | Monoclonal |
Host : | Mouse IgG1 Clone #94801 |
Applications : | CyTOF-ready, ELISA Capture, Flow Cytometry, Western Blot |
Simple Plex Cartridge Kit for quantitation of HVEM. Includes wash buffer and sample diluent. For use with the Ella automated immunoassay system.
Clonality : | Monoclonal |
Host : | Mouse IgG1 Clone #94804 |
Applications : | Immunohistochemistry |
Clonality : | Polyclonal |
Host : | Goat IgG |
Applications : | Western Blot |
Clonality : | Polyclonal |
Host : | Goat IgG |
Applications : | ELISA Detection, Western Blot |
Clonality : | Polyclonal |
Host : | Goat IgG |
Applications : | Immunohistochemistry, Western Blot |
Clonality : | Polyclonal |
Host : | Goat IgG |
Applications : | Western Blot |
Recombinant Monoclonal Antibody.
Clonality : | Monoclonal |
Host : | Rabbit IgG Clone #2742B |
Applications : | Block/Neutralize, Flow Cytometry |
Source : | HEK293 |
Accession # : | XP_005545061 |
Applications : | Bioactivity |
Source : | CHO |
Accession # : | NP_849262 |
Applications : | Binding Activity |
Source : | HEK293 |
Accession # : | Q92956.3 |
Applications : | Bioactivity |
Source : | NS0 |
Accession # : | Q92956.3 |
Applications : | Bioactivity |
Recombinant Monoclonal Antibody.
Clonality : | Monoclonal |
Host : | Rabbit IgG Clone #2024B |
Applications : | Flow Cytometry |
Recombinant Monoclonal Antibody.
Clonality : | Monoclonal |
Host : | Rabbit IgG Clone #2024B |
Applications : | Flow Cytometry |