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HVEM/TNFRSF14 Products
HVEM/TNFRSF14 (herpesvirus entry mediator) is a transmembrane protein that is most highly expressed on naïve, memory, and regulatory T cells but declines during T cell activation. It is present at low levels on most resting leukocytes. HVEM is a receptor for BTLA, CD160, and LIGHT. A cis interaction between HVEM and BTLA promotes cell survival, while trans interaction promotes a state of lymphocyte inactivity. LIGHT is expressed following T cell activation and competes with BTLA for HVEM binding, leading to a proinflammatory response. The herpesvirus envelope glycoprotein gD, which binds HVEM to initiate membrane fusion, can antagonize both BTLA and LIGHT binding. Human, but not mouse, HVEM can also bind lymphotoxin-alpha.
48 results for "HVEM/TNFRSF14" in Products
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HVEM/TNFRSF14 Products
HVEM/TNFRSF14 (herpesvirus entry mediator) is a transmembrane protein that is most highly expressed on naïve, memory, and regulatory T cells but declines during T cell activation. It is present at low levels on most resting leukocytes. HVEM is a receptor for BTLA, CD160, and LIGHT. A cis interaction between HVEM and BTLA promotes cell survival, while trans interaction promotes a state of lymphocyte inactivity. LIGHT is expressed following T cell activation and competes with BTLA for HVEM binding, leading to a proinflammatory response. The herpesvirus envelope glycoprotein gD, which binds HVEM to initiate membrane fusion, can antagonize both BTLA and LIGHT binding. Human, but not mouse, HVEM can also bind lymphotoxin-alpha.
48 results for "HVEM/TNFRSF14" in Products
Contains 4 membranes-each spotted in duplicate with 41 different proteins and 4 serine or tyrosine phosphorylation sites antibodies
Catalog #:
SPCK-PANEL
Design and order Simple Plex cartridges tailor made to meet your needs with customizable Simple Plex Assay panels for the Ella platform.
Catalog #:
FCSTM24
Luminex High Performance Assays go through rigorous development, validation, and quality control testing to ensure you are getting the best performance out of your multiplex assay. Panels are customizable so you can order a selection of the analytes or the entire panel.
Catalog #:
FAB356R
Flow
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #94801 |
| Applications : | Flow Cytometry |
Catalog #:
DY356
ELISA
| Assay Range : | 15.6 - 1,000 pg/mL |
| Applications : | ELISA |
Catalog #:
MAB2516
Flow
Recombinant Monoclonal Antibody.
| Clonality : | Monoclonal |
| Host : | Rabbit IgG Clone #2024B |
| Applications : | Flow Cytometry |
Catalog #:
FAB356G
Flow
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #94801 |
| Applications : | Flow Cytometry |
Catalog #:
MAB3562
IHC
Recombinant Monoclonal Antibody.
| Clonality : | Monoclonal |
| Host : | Rabbit IgG Clone #2742C |
| Applications : | Immunohistochemistry |
Flow
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #94801 |
| Applications : | Flow Cytometry |
WB, Flow, CyTOF-ready
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #94801 |
| Applications : | CyTOF-ready, ELISA Capture, Flow Cytometry, Western Blot |
Catalog #:
SPCKB-PS-003550
Simple Plex Cartridge Kit for quantitation of HVEM. Includes wash buffer and sample diluent. For use with the Ella automated immunoassay system.
IHC
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #94804 |
| Applications : | Immunohistochemistry |
Catalog #:
BAF2516
WB
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | Western Blot |
Catalog #:
BAF356
WB
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | ELISA Detection, Western Blot |
WB, IHC
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | Immunohistochemistry, Western Blot |
Catalog #:
AF2516
WB
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | Western Blot |
Catalog #:
MAB3563
Flow, Neut
Recombinant Monoclonal Antibody.
| Clonality : | Monoclonal |
| Host : | Rabbit IgG Clone #2742B |
| Applications : | Block/Neutralize, Flow Cytometry |
Catalog #:
9197-HV
BA
| Source : | HEK293 |
| Accession # : | XP_005545061 |
| Applications : | Bioactivity |
Catalog #:
2516-HV
Bind
| Source : | CHO |
| Accession # : | NP_849262 |
| Applications : | Binding Activity |
Catalog #:
AFG11177
BA
| Source : | HEK293 |
| Accession # : | Q92956.3 |
| Applications : | Bioactivity |
Catalog #:
356-HV/CF
BA
| Source : | NS0 |
| Accession # : | Q92956.3 |
| Applications : | Bioactivity |
Catalog #:
FAB2516G
Flow
Recombinant Monoclonal Antibody.
| Clonality : | Monoclonal |
| Host : | Rabbit IgG Clone #2024B |
| Applications : | Flow Cytometry |
Catalog #:
FAB2516R
Flow
Recombinant Monoclonal Antibody.
| Clonality : | Monoclonal |
| Host : | Rabbit IgG Clone #2024B |
| Applications : | Flow Cytometry |
