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HVEM/TNFRSF14 Products

HVEM/TNFRSF14 (herpesvirus entry mediator) is a transmembrane protein that is most highly expressed on naïve, memory, and regulatory T cells but declines during T cell activation. It is present at low levels on most resting leukocytes. HVEM is a receptor for BTLA, CD160, and LIGHT. A cis interaction between HVEM and BTLA promotes cell survival, while trans interaction promotes a state of lymphocyte inactivity. LIGHT is expressed following T cell activation and competes with BTLA for HVEM binding, leading to a proinflammatory response. The herpesvirus envelope glycoprotein gD, which binds HVEM to initiate membrane fusion, can antagonize both BTLA and LIGHT binding. Human, but not mouse, HVEM can also bind lymphotoxin-alpha.

48 results for "HVEM/TNFRSF14" in Products

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HVEM/TNFRSF14 Products

HVEM/TNFRSF14 (herpesvirus entry mediator) is a transmembrane protein that is most highly expressed on naïve, memory, and regulatory T cells but declines during T cell activation. It is present at low levels on most resting leukocytes. HVEM is a receptor for BTLA, CD160, and LIGHT. A cis interaction between HVEM and BTLA promotes cell survival, while trans interaction promotes a state of lymphocyte inactivity. LIGHT is expressed following T cell activation and competes with BTLA for HVEM binding, leading to a proinflammatory response. The herpesvirus envelope glycoprotein gD, which binds HVEM to initiate membrane fusion, can antagonize both BTLA and LIGHT binding. Human, but not mouse, HVEM can also bind lymphotoxin-alpha.

48 results for "HVEM/TNFRSF14" in Products

Contains 4 membranes-each spotted in duplicate with 41 different proteins and 4 serine or tyrosine phosphorylation sites antibodies

Catalog #: FAB356R
Flow
ELISA
Flow

Recombinant Monoclonal Antibody.

Catalog #: FAB356G
Flow
IHC

Recombinant Monoclonal Antibody.

WB, Flow, CyTOF-ready

Simple Plex Cartridge Kit for quantitation of HVEM. Includes wash buffer and sample diluent. For use with the Ella automated immunoassay system.

BA

Biotinylated

Catalog #: BAF2516
WB
Catalog #: BAF356
WB
WB
Flow, Neut

Recombinant Monoclonal Antibody.

BA
Bind
BA
Catalog #: FAB2516G
Flow

Recombinant Monoclonal Antibody.

Flow

Recombinant Monoclonal Antibody.

Catalog #: RDC1584
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