Skip to main content

HVEM/TNFRSF14: Antibodies

HVEM/TNFRSF14 (herpesvirus entry mediator) is a transmembrane protein that is most highly expressed on naïve, memory, and regulatory T cells but declines during T cell activation. It is present at low levels on most resting leukocytes. HVEM is a receptor for BTLA, CD160, and LIGHT.

A cis interaction between HVEM and BTLA promotes cell survival, while trans interaction promotes a state of lymphocyte inactivity. LIGHT is expressed following T cell activation and competes with BTLA for HVEM binding, leading to a proinflammatory response. The herpesvirus envelope glycoprotein gD, which binds HVEM to initiate membrane fusion, can antagonize both BTLA and LIGHT binding. Human, but not mouse, HVEM can also bind lymphotoxin-alpha.

Products:

Show More

158 results for "HVEM/TNFRSF14 Primary Antibodies" in Products

Back to Search Results
Apply

HVEM/TNFRSF14: Antibodies

HVEM/TNFRSF14 (herpesvirus entry mediator) is a transmembrane protein that is most highly expressed on naïve, memory, and regulatory T cells but declines during T cell activation. It is present at low levels on most resting leukocytes. HVEM is a receptor for BTLA, CD160, and LIGHT.

A cis interaction between HVEM and BTLA promotes cell survival, while trans interaction promotes a state of lymphocyte inactivity. LIGHT is expressed following T cell activation and competes with BTLA for HVEM binding, leading to a proinflammatory response. The herpesvirus envelope glycoprotein gD, which binds HVEM to initiate membrane fusion, can antagonize both BTLA and LIGHT binding. Human, but not mouse, HVEM can also bind lymphotoxin-alpha.

Products:

Show More

158 results for "HVEM/TNFRSF14 Primary Antibodies" in Products

WB, Flow, CyTOF-ready
Catalog #: FAB2516N
Flow

Recombinant Monoclonal Antibody.

Catalog #: FAB3563N
Flow

Recombinant Monoclonal Antibody.

Flow, Neut

Recombinant Monoclonal Antibody.

Catalog #: FAB356T
Flow
Catalog #: FAB3563U
Flow

Recombinant Monoclonal Antibody.

ICC/IF, IHC, WB

Recombinant Monoclonal Antibody

Catalog #: BAF356
WB
WB
Flow

Recombinant Monoclonal Antibody.

IHC

Recombinant Monoclonal Antibody.

ELISA, ICC/IF, IHC, WB
Catalog #: BAF2516
WB
Flow

Recombinant Monoclonal Antibody.

Flow

Recombinant Monoclonal Antibody.

Catalog #: FAB356U
Flow
Catalog #: FAB356G
Flow
Catalog #: FAB356N
Flow
Catalog #: FAB356V
Flow
Catalog #: FAB356S
Flow
Catalog #: FAB356R
Flow
Catalog #: FAB3563T
Flow

Recombinant Monoclonal Antibody.

Results Per Page
5 10 25 50
/ 7