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E-Selectin/CD62E Products
E-Selectin, also known as CD62E, is expressed on vascular endothelial cells in response to IL-1 beta and TNF-alpha. It is a lectin that binds to sialylated or fucosylated molecules on neutrophils, monocytes, and a subset of memory T cells. E-Selectin mediates the initial attachment of circulating leukocytes to the blood vessel wall during inflammation. This interaction permits leukocytes to roll along the vascular endothelium. Subsequent ICAM-1 and VCAM-1 mediated adhesion leads to extravasation of the leukocyte through the blood vessel wall into the extracellular matrix tissue.
40 results for "E-Selectin/CD62E" in Products
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E-Selectin/CD62E Products
E-Selectin, also known as CD62E, is expressed on vascular endothelial cells in response to IL-1 beta and TNF-alpha. It is a lectin that binds to sialylated or fucosylated molecules on neutrophils, monocytes, and a subset of memory T cells. E-Selectin mediates the initial attachment of circulating leukocytes to the blood vessel wall during inflammation. This interaction permits leukocytes to roll along the vascular endothelium. Subsequent ICAM-1 and VCAM-1 mediated adhesion leads to extravasation of the leukocyte through the blood vessel wall into the extracellular matrix tissue.
40 results for "E-Selectin/CD62E" in Products
Contains 4 membranes-each spotted in duplicate with 111 different cytokine antibodies
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Contains 4 membranes-each spotted in duplicate with 84 different cancer-related antibodies
| Source : | CHO |
| Accession # : | P16581 |
| Applications : | Bioactivity |
| Sensitivity : | 0.027 ng/mL |
| Assay Range : | 0.125 - 8 ng/mL (Cell Culture Supernates, Serum, Heparin Plasma, Citrate Plasma) |
| Applications : | ELISA |
Contains 4 membranes - 2 spotted in duplicate with 62 different non-hematopoietic antibodies and 2 spotted in duplicate with 57 common antibodies
Simple Plex Human E-Selectin/CD62E assay kit for use on Ella instrument. Contains cartridge, sample diluent SD13, and wash buffer.
| Source : | NS0 |
| Accession # : | P16581 |
| Applications : | Bioactivity |
Clone BBIG-E4 was used by HLDA to establish CD designation
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #BBIG-E4 |
| Applications : | ELISA Capture, Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot |
| Assay Range : | 93.8 - 6,000 pg/mL |
| Applications : | ELISA |
| Clonality : | Monoclonal |
| Host : | Rat IgG2a Clone #96403 |
| Applications : | Western Blot |
| Clonality : | Polyclonal |
| Host : | Sheep IgG |
| Applications : | Block/Neutralize, Western Blot |
| Clonality : | Polyclonal |
| Host : | Chicken IgY |
| Applications : | Immunohistochemistry, Western Blot |
| Clonality : | Monoclonal |
| Host : | Rat IgG1 Clone #96419 |
| Applications : | ELISA Capture, Western Blot |
Selective inhibitor of E-selectin and ICAM-1 expression
| Chemical Name : | 4-[(4-Methylphenyl)thio]thieno[2,3-c]pyridine-2-carboxamide |
| Purity : | ≥98% (HPLC) |
| Assay Range : | 62.5 - 4,000 pg/mL |
| Applications : | ELISA |
| Sensitivity : | 4.7 pg/mL |
| Assay Range : | 15.6 - 1,000 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma) |
| Applications : | ELISA |
| Clonality : | Polyclonal |
| Host : | Sheep IgG |
| Applications : | Western Blot |
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | Block/Neutralize, Immunohistochemistry, Western Blot |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #BBIG-E5 |
| Applications : | ELISA Detection, Immunocytochemistry/Immunofluorescence, Western Blot |
| Source : | NS0 |
| Accession # : | P98105 |
| Applications : | Bioactivity |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #BBIG-E6 (13D5) |
| Applications : | Block/Neutralize, CyTOF-ready, Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunoprecipitation |
| Source : | NS0 |
| Accession # : | Q00690 |
| Applications : | Bioactivity |
