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Dectin-1/CLEC7A Products

Dectin-1, also known as CLEC7A, is a transmembrane C-type lectin that participates in the innate immune response to fungal pathogens. It is expressed on the surface of monocytes, macrophages, myeloid DC, neutrophils, eosinophils, B cells, and CD4+ T cells. Dectin-1 selectively binds beta-glucan polymers, a major component of yeast and mycobacterial cell walls. Dectin-1 mediates the phagocytosis of zymosan particles and intact yeast. Dectin-1 colocalizes with TLR2 in the presence of zymosan, and the two receptors cooperate in ligand recognition and the propagation of proinflammatory signaling. Dectin-1 also interacts with tetraspanin CD37 which increases its stability on the cell membrane and inhibits ligand-induced signaling.

31 results for "Dectin-1/CLEC7A" in Products

Dectin-1/CLEC7A Products

Dectin-1, also known as CLEC7A, is a transmembrane C-type lectin that participates in the innate immune response to fungal pathogens. It is expressed on the surface of monocytes, macrophages, myeloid DC, neutrophils, eosinophils, B cells, and CD4+ T cells. Dectin-1 selectively binds beta-glucan polymers, a major component of yeast and mycobacterial cell walls. Dectin-1 mediates the phagocytosis of zymosan particles and intact yeast. Dectin-1 colocalizes with TLR2 in the presence of zymosan, and the two receptors cooperate in ligand recognition and the propagation of proinflammatory signaling. Dectin-1 also interacts with tetraspanin CD37 which increases its stability on the cell membrane and inhibits ligand-induced signaling.

31 results for "Dectin-1/CLEC7A" in Products

Contains 4 membranes - each spotted in duplicate with 59 different immunoreceptor antibodies

Flow, Block, CyTOF-ready, ICC

Clone 259931 was used by HLDA to establish CD designation

BA

HEK293 Expressed

WB, Block
Catalog #: FAB17561R
Flow
Flow, Block, CyTOF-ready
Bind
Catalog #: FAB1859R
Flow

Clone 259931 was used by HLDA to establish CD designation

Flow
Catalog #: BAF1859
WB
WB, Flow, Block, CyTOF-ready
Catalog #: FAB1859G
Flow

Clone 259931 was used by HLDA to establish CD designation

Clone 259931 was used by HLDA to establish CD designation

Flow

Clone 259931 was used by HLDA to establish CD designation

Flow
Catalog #: FAB17561V
Flow
Catalog #: FAB17561U
Flow
Catalog #: FAB1859T
Flow

Clone 259931 was used by HLDA to establish CD designation

Catalog #: FAB1859U
Flow

Clone 259931 was used by HLDA to establish CD designation

Catalog #: FAB1859V
Flow

Clone 259931 was used by HLDA to establish CD designation

Catalog #: FAB1859S
Flow

Clone 259931 was used by HLDA to establish CD designation

Clone 259931 was used by HLDA to establish CD designation

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