Skip to main content

Dectin-1/CLEC7A: Antibodies

Dectin-1, also known as CLEC7A, is a transmembrane C-type lectin that participates in the innate immune response to fungal pathogens. It is expressed on the surface of monocytes, macrophages, myeloid DC, neutrophils, eosinophils, B cells, and CD4+ T cells. Dectin-1 selectively binds beta-glucan polymers, a major component of yeast and mycobacterial cell walls.

Dectin-1 mediates the phagocytosis of zymosan particles and intact yeast. Dectin-1 colocalizes with TLR2 in the presence of zymosan, and the two receptors cooperate in ligand recognition and the propagation of proinflammatory signaling. Dectin-1 also interacts with tetraspanin CD37 which increases its stability on the cell membrane and inhibits ligand-induced signaling.

Products:

Show More

206 results for "Dectin-1/CLEC7A Primary Antibodies" in Products

Back to Search Results
Apply

Dectin-1/CLEC7A: Antibodies

Dectin-1, also known as CLEC7A, is a transmembrane C-type lectin that participates in the innate immune response to fungal pathogens. It is expressed on the surface of monocytes, macrophages, myeloid DC, neutrophils, eosinophils, B cells, and CD4+ T cells. Dectin-1 selectively binds beta-glucan polymers, a major component of yeast and mycobacterial cell walls.

Dectin-1 mediates the phagocytosis of zymosan particles and intact yeast. Dectin-1 colocalizes with TLR2 in the presence of zymosan, and the two receptors cooperate in ligand recognition and the propagation of proinflammatory signaling. Dectin-1 also interacts with tetraspanin CD37 which increases its stability on the cell membrane and inhibits ligand-induced signaling.

Products:

Show More

206 results for "Dectin-1/CLEC7A Primary Antibodies" in Products

Flow, Block, CyTOF-ready, ICC

Clone 259931 was used by HLDA to establish CD designation

WB, Flow, Block, CyTOF-ready

Clone 259931 was used by HLDA to establish CD designation

WB, Block
Flow, Block, CyTOF-ready

Clone 259931 was used by HLDA to establish CD designation

Catalog #: FAB1859G
Flow

Clone 259931 was used by HLDA to establish CD designation

Catalog #: BAF1859
WB
Flow
Flow
Flow
Flow

Clone 259931 was used by HLDA to establish CD designation

Catalog #: FAB17561V
Flow
Catalog #: FAB17561R
Flow
Catalog #: FAB1859T
Flow

Clone 259931 was used by HLDA to establish CD designation

Catalog #: FAB1859U
Flow

Clone 259931 was used by HLDA to establish CD designation

Catalog #: FAB1859R
Flow

Clone 259931 was used by HLDA to establish CD designation

Catalog #: FAB1859V
Flow

Clone 259931 was used by HLDA to establish CD designation

Catalog #: FAB1859S
Flow

Clone 259931 was used by HLDA to establish CD designation

Catalog #: FAB17561U
Flow
Catalog #: FAB17561S
Flow
Results Per Page
5 10 25 50
/ 9