19 results for "Cytokine Compounds" in Products
Cytokine Compounds Products
Cytokines are proteinaceous signaling compounds that are major mediators of the immune response. They control many different cellular functions including proliferation, differentiation and cell survival/apoptosis but are also involved in several pathophysiological processes including viral infections and autoimmune diseases.
Cytokines are synthesized under various stimuli by a variety of cells of both the innate (monocytes, macrophages, dendritic cells) and adaptive (T- and B-cells) immune ...
Antifibrotic agent; regulates cytokine levels in vivo
| Chemical Name: | 5-methyl-1-phenyl-2(1H)-pyridinone |
| Purity: | ≥98% (HPLC) |
Macrophage migration inhibitory factor (MIF) inhibitor
| Chemical Name: | 4,5-Dihydro-3-(4-hydroxyphenyl)-5-isoxazoleacetic acid methyl ester |
| Purity: | ≥98% (HPLC) |
Binds cereblon; also TNF-α synthesis inhibitor
| Chemical Name: | N-(2,6-dioxo-3-piperidinyl)phthalimide |
| Purity: | ≥98% (HPLC) |
Immunomodulatory and antitumor compound
| Chemical Name: | 2-Amino-5-bromo-6-phenyl-4(3H)-pyrimidone |
| Purity: | ≥98% (HPLC) |
MIF binder
| Chemical Name: | 2-(2-Pyridinyl)-4H-1,3-benzothiazin-4-one |
| Purity: | ≥98% (HPLC) |
Potent NLRP3 inflammasome inhibitor
| Chemical Name: | 2-((1,2,3,5,6,7-Hexahydro-s-indacen-4-yl)amino)-5-(pyridin-2-ylmethyl)-[1,2,4]triazolo[1,5-a]pyrimidine-7(4H)-thione |
| Purity: | ≥95% (HPLC) |
Immunomodulator; reduces production of pro-inflammatory cytokines
| Chemical Name: | 4,5-Dihydro-3-phenyl-5-isoxazoleacetic acid |
| Purity: | ≥98% (HPLC) |
Inhibitor of macrophage migration inhibitory factor (MIF); suicide substrate
| Chemical Name: | 4-Iodo-6-phenylpyrimidine |
| Purity: | ≥98% (HPLC) |
Suppressor of MDK expression; inhibits PI 3-K signaling
| Chemical Name: | 3-[2-[(4-Fluorophenyl)methyl]imidazo[2,1-b]thiazol-6-yl]-2H-1-benzopyran-2-one |
| Purity: | ≥98% (HPLC) |
Cereblon binder; also TNF-α inhibitor and antiangiogenic
| Chemical Name: | 4-Amino-2-(2,6-dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione |
| Purity: | ≥98% (HPLC) |
TIR-TIR interaction inhibitor
| Chemical Name: | 1-Methyl-2,5-bis[[[(1S)-2-methyl-1-(1-pyrrolidinylcarbonyl)propyl](3-phenylpropyl)amino]carbonyl]pyridinium iodide |
| Purity: | ≥98% (HPLC) |
Cereblon binder; induces ubiquitination and degradation of CK1α by E3 ubiquitin ligase
| Chemical Name: | 3-(4-Amino-1,3-dihydro-1-oxo-2H-isoindol-2-yl)-2,6-piperidinedione |
| Purity: | ≥98% (HPLC) |
Active metabolite binds CPSF3; Pro-drug
| Alternate Names: | TO-207 |
| Chemical Name: | N-[3,5-Dichloro-2-hydroxy-4-[2-(4-methyl-1-piperazinyl)ethoxy]benzoyl]-L-phenylalanine ethyl ester dihydrochloride |
| Purity: | ≥98% (HPLC) |
TRAF6-Ubc13 interaction inhibitor
| Chemical Name: | 3-[3,5-Dimethyl-1-(3-methyl-1,2,4-triazolo[4,3-b]pyridazin-6-yl)-1H-pyrazol-4-yl]-1-[4-(phenylmethyl)-1-piperidinyl]-1-propanone |
| Purity: | ≥98% (HPLC) |
gp130 agonist; brain penetrant and neuroprotectant
| Chemical Name: | N-(4-Fluorophenyl)-4-phenyl-2-thiazolamine |
| Purity: | ≥98% (HPLC) |
Serine protease inhibitor; inhibits thrombin, trypsin, kallikrein and plasmin
| Alternate Names: | FOY |
| Chemical Name: | 4-[[6-[(Aminoiminomethyl)amino]-1-oxohexyl]oxy]-benzoic acid ethyl ester mesylate |
| Purity: | ≥98% (HPLC) |
NLRP3 inflammasome inhibitor
| Alternate Names: | JC121 |
| Chemical Name: | N-[2-[4-(Aminosulfonyl)phenyl]ethyl]-5-chloro-2-methoxybenzamide |
| Purity: | ≥98% (HPLC) |
Potent and selective IRAK4 inhibitor
| Chemical Name: | N-[3-Aminocarbonyl)-1-(tetrahydro-2H-pyran-4-yl)-1H-pyrazol-4-yl]-2-(2-methyl-4-pyridinyl)-4-oxazolecarboxamide hydrochloride |
| Purity: | ≥98% (HPLC) |
Selective Syk kinase inhibitor
| Chemical Name: | 10-(3-Aminopropyl)-3,4-dimethyl-9(10H)-acridinone maleate |
| Purity: | ≥98% (HPLC) |
