Bropirimine

Name: Bropirimine
Brand: Tocris Bioscience
SKU: 4316
Rating: 5 (1 reviews)

Tocris Bioscience, part of Bio-Techne | Catalog # 4316

(1)

Citations (2)

COA / SDS

Immunomodulatory and antitumor compound

Key Product Details

Description:	Immunomodulatory and antitumor compound
Chemical Name:	2-Amino-5-bromo-6-phenyl-4(3H)-pyrimidone
Purity:	≥98% (HPLC)
Molecular Weight:	266.09

View Full Technical Details for Bropirimine

Technical Data
Citations / Reviews (1)

Biological Activity for Bropirimine

Bropirimine is a immunomodulatory and antitumor compound. Induces interferon (IFN)-α/β production; augments natural killer (NK) cell activity. Orally active.

Technical Data for Bropirimine

M. Wt	266.09
Formula	C₁₀H₈BrN₃O
Storage	Desiccate at RT
Purity	≥98% (HPLC)
CAS Number	56741-95-8
PubChem ID	65457
InChi Key	CIUUIPMOFZIWIZ-UHFFFAOYSA-N
Smiles	O=C1N=C(N)NC(C2=CC=CC=C2)=C1Br

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for Bropirimine

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
Solubility	DMSO	26.61	100

Preparing Stock Solutions for Bropirimine

The following data is based on the product molecular weight 266.09.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	3.76 mL	18.79 mL	37.58 mL
5 mM	0.75 mL	3.76 mL	7.52 mL
10 mM	0.38 mL	1.88 mL	3.76 mL
50 mM	0.08 mL	0.38 mL	0.75 mL

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Reconstitution Calculator

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References for Bropirimine

References are publications that support the biological activity of the product.

Tei In vitro antitumor activity of bropirimine against urinary bladder tumor cells. Anticancer Res. 2002 PMID: 12168852
Fujioka Antitumor effects of oral administration of an IF.-inducing pyrimidinone, Bropirimine, on murine renal-cell carcinoma. Cancer Chemother.Pharmacol. 1995 PMID: 7536641