Pirfenidone

Tocris Bioscience, part of Bio-Techne | Catalog # 1093

Antifibrotic agent; regulates cytokine levels in vivo
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Key Product Details

Description

Antifibrotic agent; regulates cytokine levels in vivo

View all Cytokine Compounds »

Product Description

Pirfenidone is a antifibrotic agent, effective in models of pulmonary and lung fibrosis. Inhibits collagen production and fibroblast proliferation. Regulates cytokine levels following oral administration in vivo. Potent scavenger of free radicals and inhibitor of lipid peroxidation.

Product Specifications

Molecular Weight

185.23

Formula

C12H11NO

Storage

Store at RT

Purity

≥98% (HPLC)

Chemical Name

5-methyl-1-phenyl-2(1H)-pyridinone

CAS Number

53179-13-8

PubChem ID

40632

InChI Key

ISWRGOKTTBVCFA-UHFFFAOYSA-N

SMILES

CC1=CN(C(=O)C=C1)C1=CC=CC=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 3.7 20

Preparing Stock Solutions for Pirfenidone

The following data is based on the product molecular weight 185.23

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.2 mM 26.99 mL 134.97 mL 269.93 mL
1 mM 5.40 mL 26.99 mL 53.99 mL
2 mM 2.70 mL 13.50 mL 26.99 mL
10 mM 0.54 mL 2.70 mL 5.40 mL

Calculators

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Background References

References are publications that support the biological activity of the product.

Product Documents for Pirfenidone

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Pirfenidone

For research use only

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