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Cyclooxygenase Inhibitors: Small Molecules and Peptides

Cyclooxygenase (COX), also known as prostaglandin G/H synthase, is a membrane bound enzyme partly responsible for the catalysis of prostanoid synthesis. COX is expressed as at least three different isoforms. COX-1 is constitutively expressed and thought to regulate a number of 'housekeeping' functions such as vascular hemostasis, renal blood flow, and glomerular function. COX-2 expression is tightly regulated and induced by inflammatory mediators such as growth factors, cytokines, and endotoxin. COX-3 appears to be much more strictly regulated spatially and is observed in greatest abundance in cerebral cortex.

20 results for "Cyclooxygenase Inhibitors Small Molecules and Peptides" in Products

Cyclooxygenase Inhibitors: Small Molecules and Peptides

Cyclooxygenase (COX), also known as prostaglandin G/H synthase, is a membrane bound enzyme partly responsible for the catalysis of prostanoid synthesis. COX is expressed as at least three different isoforms. COX-1 is constitutively expressed and thought to regulate a number of 'housekeeping' functions such as vascular hemostasis, renal blood flow, and glomerular function. COX-2 expression is tightly regulated and induced by inflammatory mediators such as growth factors, cytokines, and endotoxin. COX-3 appears to be much more strictly regulated spatially and is observed in greatest abundance in cerebral cortex.

20 results for "Cyclooxygenase Inhibitors Small Molecules and Peptides" in Products

Cyclooxygenase inhibitor; NSAID

Cyclooxygenase inhibitor

Cyclooxygenase inhibitor (COX-1 > COX-2)

Cyclooxygenase inhibitor

Cyclooxygenase inhibitor; may be selective for COX-3

Cyclooxygenase inhibitor (COX-1 > COX-2)

Cyclooxygenase inhibitor; NSAID

Cyclooxygenase-2 (COX-2) inhibitor; GPR35 agonist

Selective cyclooxygenase-2 (COX-2) inhibitor

Cyclooxygenase-2 (COX-2) inhibitor

Selective cyclooxygenase-2 (COX-2) inhibitor

Cyclooxygenase-2 (COX-2) inhibitor

NSAID, cyclooxygenase (COX-1) inhibitor. Also opener of KIR2.3

Cyclooxygenase (COX-1) inhibitor

Cyclooxygenase-1 (COX-1) inhibitor

Cyclooxygenase-2 (COX-2) inhibitor

Selective cyclooxygenase-2 (COX-2) inhibitor

Selective and potent COX-2 inhibitor

CaCC blocker and Cl-/HCO3- exchange inhibitor

Calcium-activated chloride channel blocker; NSAID. Also activates TRPC6

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