Aspirin
Tocris Bioscience, part of Bio-Techne | Catalog # 4092
Cyclooxygenase inhibitor; NSAID
Key Product Details
Description
Cyclooxygenase inhibitor; NSAID
Product Description
Aspirin is an inhibitor of cyclooxygenase (COX)-1. Blocks the production of prostaglandins and thromboxanes. Exhibits antiplatelet and antithrombotic activities. Displays anticancer effects in some solid tumors. One of the first described NSAID drugs.Product Specifications
Molecular Weight
180.16
Formula
C9H8O4
Storage
Store at RT
Purity
≥98% (HPLC)
Chemical Name
2-Acetoxybenzoic acid
CAS Number
50-78-2
PubChem ID
2244
InChI Key
BSYNRYMUTXBXSQ-UHFFFAOYSA-N
SMILES
CC(OC1=C(C(O)=O)C=CC=C1)=O
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| water | 1.8 | 10 | |
| DMSO | 18.02 | 100 |
Preparing Stock Solutions
for Aspirin
The following data is based on the product molecular weight 180.16
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 5.55 mL | 27.75 mL | 55.51 mL |
| 5 mM | 1.11 mL | 5.55 mL | 11.10 mL |
| 10 mM | 0.56 mL | 2.78 mL | 5.55 mL |
| 50 mM | 0.11 mL | 0.56 mL | 1.11 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Wu Aspirin inhibits interleukin 1-induced prostaglandin H synthase expression in cultured endothelial cells. Proc.Natl.Acad.Sci.U.S.A. 1991 PMID: 1900943
- Baron Aspirin and cancer. Preventative Medicine 1995 PMID: 7597012
- Schror Aspirin and platelets: the antiplatelet action of aspirin and its role in thrombosis treatment and prophylaxis. Semin.Thromb.Hemost. 1997 PMID: 9263351
Product Specific Notices for Aspirin
For research use only
⚠ WARNING: This product can expose you to chemicals including Aspirin (NOTE: It is especially important not to use aspirin during the last three months of pregnancy, unless specifically directed to do so by a physician because it may cause problems in the unborn child or complications during delivery.), which is known to the State of California to cause reproductive toxicity with developmental effects. For more information, go to www.P65Warnings.ca.gov
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