14 results for "Class II Histone Deacetylases Inhibitors" in Products
Class II Histone Deacetylases Inhibitors Products
HDAC classification
| Superfamily | Family | Class | Subclass | Protein (human) |
|---|---|---|---|---|
| Arginase/deacetylase superfamily | Histone deacetylase family | Class I | HDAC1, HDAC2, HDAC3, HDAC8 | |
| Class II | Class IIa | HDAC4, HDAC5, HDAC7, HDAC9 | ||
| ClassIIb | HDAC6, HDAC10 | |||
| Class IV | HDAC11 | |||
| Deoxyhypusine synthase like NAD/FAD-binding domain superfamily | Sir2 regulator family | Class III | I | SIRT1, SIRT2, SIRT3 |
| II | SIRT4 | |||
| III | SIRT5 | |||
| IV | SIRT6, SIRT7 |
Histone deacetylase inhibitor
| Alternate Names: | VPA,Sodium Valproate |
| Chemical Name: | Sodium 2-propylpentanoate |
Potent histone deacetylase inhibitor
| Chemical Name: | (2E,4E,6R)-7-(4-(Dimethylamino)phenyl)-N-hydroxy-4,6-dimethyl-7-oxo-2,4-heptadienamide |
| Purity: | ≥95% (HPLC) |
Histone deacetylase inhibitor
| Chemical Name: | Butanoic acid sodium salt |
Histone deacetylase inhibitor
| Alternate Names: | 4-PB,Sodium phenylbutyrate |
| Chemical Name: | 4-Phenylbutyric acid, sodium salt |
| Purity: | ≥98% (HPLC) |
Histone deacetylase inhibitor
| Alternate Names: | ITF 2357 |
| Chemical Name: | [6-[(Diethylamino)methyl]-2-naphthalenyl]methyl-N-[4-[(hydroxyamino)carbonyl]phenyl]carbamate hydrochloride |
| Purity: | ≥98% (HPLC) |
Pan-histone deacetylase inhibitor
| Chemical Name: | (2E)-N-Hydroxy-3-[4-[[[2-(2-methyl-1H-indol-3-yl)ethyl]amino]methyl]phenyl]-2-propenamide |
| Purity: | ≥98% (HPLC) |
Class I and II HDAC inhibitor
| Alternate Names: | Vorinostat |
| Chemical Name: | N-Hydroxy-N'-phenyloctanediamide |
| Purity: | ≥98% (HPLC) |
Dual histone deacetylase (HDAC) 6/8 inhibitor
| Chemical Name: | N1-Hydroxy-N3-(2-phenylethyl)-1,3-benzenedicarboxamide |
| Purity: | ≥98% (HPLC) |
HDAC6 inhibitor; inhibits α-tubulin deacetylation
| Chemical Name: | N-[4-[(2R,4R,6S)-4-[[(4,5-Diphenyl-2-oxazolyl)thio]methyl]-6-[4-(hydroxymethyl)phenyl]-1,3-dioxan-2-yl]phenyl]-N'-hydroxyoctanediamide |
| Purity: | ≥96% (HPLC) |
Potent class I and IIb HDAC inhibitor
| Chemical Name: | 5-[(4-[1,1'-Biphenyl]-4-yl-1,6-dihydro-6-oxo-2-pyrimidinyl)thio]-N-hydroxypentanamide |
| Purity: | ≥98% (HPLC) |
Potent and selective HDAC class IIa inhibitor
| Chemical Name: | N-((R)-1-((S)-2-Methylpyrrolidin-1-yl)propan-2-yl)-4-(5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl)benzamide |
| Purity: | ≥98% (HPLC) |
Highly potent and selective HDAC2 inhibitor
| Chemical Name: | Ethyl N-[4-oxo-4-[(2-phenylethyl)amino]butyl]carbamate |
| Purity: | ≥98% (HPLC) |
High affinity HDAC4 negative allosteric modulator; also binds S100A9; antiangiogenic
| Chemical Name: | 1,2-dihydro-4-hydroxy-5-methoxy-N,1-dimethyl-2-oxo-N-[4-(trifluoromethyl)phenyl]-3-quinolinecarboxamide |
| Purity: | ≥98% (HPLC) |
Potent and selective HDAC4 Degrader (PROTAC®)
| Chemical Name: | (2S,4R)-1-((3R,26S)-26-(tert-Butyl)-3-methyl-1,24-dioxo-5-propyl-1-(4-(5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl)phenyl)-10,13,16,19,22-pentaoxa-2,5,25-triazaheptacosan-27-oyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide |
| Purity: | ≥98% (HPLC) |
