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Cell Cycle Inhibitors Products
19 results for "Cell Cycle Inhibitors" in Products
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Cell Cycle Inhibitors Products
19 results for "Cell Cycle Inhibitors" in Products
Potent and selective CDK7 inhibitor; induces cell cycle arrest
| Chemical Name : | N-[(1S)-2-(Dimethylamino)-1-phenylethyl]-4,6-dihydro-6,6-dimethyl-3-[[4-[(1-oxo-2-propen-1-yl)amino]benzoyl]amino]pyrrolo[3,4-c]pyrazole-5(1H)-carboxamide |
| Purity : | ≥95% (HPLC) |
BET bromodomain inhibitor; arrests cell cycle at G1 phase
| Alternate Names : | TEN 010 |
| Chemical Name : | (6S)-4-(4-Chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetamide |
| Purity : | ≥98% (HPLC) |
Stabilizes G-quadruplexes; induces DNA damage and cell cycle arrest
| Chemical Name : | 4-(2-Aminoethoxy)N2,N6-bis[(4-(2-aminoethoxy)-2-quinolinyl]-2,6-pyridinecarboxamide pentahydrochloride |
| Purity : | ≥95% (HPLC) |
Stimulates RhoA activation; antiproliferative agent that slows cell cycle progression
| Chemical Name : | (2S,3R,4S,4aR)-3,4,4a,5-Tetrahydro-2,3,4,7-tetrahydroxy-(1,3)dioxolo(4,5-j)phenanthridin-6(2H)-one |
| Purity : | ≥98% (HPLC) |
Soluble guanylyl cyclase (sGC) activator; induces G1 cell cycle arrest
| Chemical Name : | 3-(5'-Hydroxymethyl-2'-furyl)-1-benzyl indazole |
| Purity : | ≥99% (HPLC) |
Cytotoxic agent
| Chemical Name : | N-[4-[[(2,4-Diamino-6-pteridinyl)methyl]methylamino]benzoyl]-L-glutamic acid |
| Purity : | ≥99% (HPLC) |
mRNA splicing inhibitor; antitumor
| Chemical Name : | (4R,7R,8S,9E,11S,12S)-8-(Acetyloxy)-4,7-dihydroxy-12-[(1E,3E,5S)-6-[(2R,3R)-3-[(1R,2S)-2-hydroxy-1-methylbutyl]-2-oxiranyl]-1,5-dimethyl-1,3-hexadien-1-yl]-7,11-dimethyloxacyclododec-9-en-2-one |
| Purity : | ≥95% (HPLC) |
GSK-3β inhibitor; also inhibits cdks and other protein kinases
| Alternate Names : | Indirubin-3'-monoxime |
| Chemical Name : | 3-[1,3-Dihydro-3-(hydroxyimino)-2H-indol-2-ylidene]-1,3-dihydro-2H-indol-2-one |
| Purity : | ≥99% (HPLC) |
Inhibits c-Myc-Max dimerization
| Chemical Name : | 5-[(4-Ethylphenyl)methylene]-2-thioxo-4-thiazolidinone |
| Purity : | ≥99% (HPLC) |
Cdk inhibitor; potently inhibits cdk1, 2, 5 and 9
| Chemical Name : | 4-[2-Methyl-1-(1-methylethyl)-1H-imidazol-5-yl]-N-[4-(methylsulfonyl)phenyl]-2-pyrimidinamine |
| Purity : | ≥99% (HPLC) |
Potent and selective Cdc7 inhibitor
| Alternate Names : | BMS 863233 |
| Chemical Name : | 8-Chloro-2-(2S)-2-pyrrolidinylbenzofuro[3,2-d]pyrimidin-4(3H)-one hydrochloride |
| Purity : | ≥99% (HPLC) |
High affinity Bcl-2 family inhibitor; proapoptotic, senolytic and antitumor
| Chemical Name : | 4-[4-[[2-(4-Chlorophenyl)-5,5-dimethyl-1-cyclohexen-1-yl]methyl]-1-piperazinyl]-N-[[4-[[(1R)-3-(4-morpholinyl)-1-[(phenylthio)methyl]propyl]amino]-3-[(trifluoromethyl)sulfonyl]phenyl]sulfonyl]benzamide |
| Purity : | ≥98% (HPLC) |
Potent and selective mTOR inhibitor
| Chemical Name : | N-[4-[4-(4-Morpholinyl)-1-[1-(3-pyridinylmethyl)-4-piperidinyl]-1H-pyrazolo[3,4-d]pyrimidin-6-yl]phenyl]-carbamic acid methyl ester dihydrochloride |
| Purity : | ≥98% (HPLC) |
Potent cdk inhibitor
| Chemical Name : | 3-[[4-[2-[(3-Chlorophenyl)amino]-4-pyrimidinyl]-2-pyridinyl]amino]-1-propanol |
| Purity : | ≥98% (HPLC) |
Cdk inhibitor
| Chemical Name : | (2R)-2-[[9-(1-Methylethyl)-6-[(phenylmethyl)amino]-9H-purin-2-yl]amino]-1-butanol |
| Purity : | ≥98% (HPLC) |
Potent covalent CDK14 and CDK16 inhibitor; also inhibits other TAIRE kinase family members
| Chemical Name : | N-[1-[[3-[[(2E)-4-(Dimethylamino)-1-oxo-2-buten-1-yl]amino]phenyl]sulfonyl]-4-piperidinyl]-4-[(2,4,6- trichlorobenzoyl)amino]-1H-pyrazole-3-carboxamide |
| Purity : | ≥98% (HPLC) |
Potent CDK14 and CDK16 inhibitor; displays reversible inhibition of CDK14
| Chemical Name : | N-(1-((3-(4-(Dimethylamino)butanamido)phenyl)sulfonyl)piperidin-4-yl)-4-(2,4,6-trichlorobenzamido)-1H-pyrazole-3-carboxamide |
| Purity : | ≥98% (HPLC) |
Cytotoxic nucleoside analog; inhibits RNA synthesis
| Chemical Name : | 6-Amino-8-chloropurine riboside |
| Purity : | ≥98% (HPLC) |
Suppresses ROS-induced activation of the NLRP3 inflammasome; antimalarial
| Chemical Name : | 4-Oxo-4-(((3R,5aS,6R,8aS,9R,10S,12R,12aR)-3,6,9-trimethyldecahydro-3H-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-10-yl)oxy)butanoic acid |
| Purity : | ≥98% (HPLC) |
