Cell Cycle Inhibitors Products
Cell cycle inhibitors slow or stop cell cycle progression via different mechanisms. Cell cycle arrest can be induced at different stages. This can decrease the rate of cell division and the number of cells that are actively cycling.
16 results for "Cell Cycle Inhibitors" in Products
16 results for "Cell Cycle Inhibitors" in Products
Cell Cycle Inhibitors Products
Cell cycle inhibitors slow or stop cell cycle progression via different mechanisms. Cell cycle arrest can be induced at different stages. This can decrease the rate of cell division and the number of cells that are actively cycling.
BET bromodomain inhibitor; arrests cell cycle at G1 phase
| Alternate Names: | TEN 010 |
| Chemical Name: | (6S)-4-(4-Chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetamide |
| Purity: | ≥98% (HPLC) |
Potent and selective CDK7 inhibitor; induces cell cycle arrest
| Chemical Name: | N-[(1S)-2-(Dimethylamino)-1-phenylethyl]-4,6-dihydro-6,6-dimethyl-3-[[4-[(1-oxo-2-propen-1-yl)amino]benzoyl]amino]pyrrolo[3,4-c]pyrazole-5(1H)-carboxamide |
| Purity: | ≥95% (HPLC) |
Stimulates RhoA activation; antiproliferative agent that slows cell cycle progression
| Chemical Name: | (2S,3R,4S,4aR)-3,4,4a,5-Tetrahydro-2,3,4,7-tetrahydroxy-(1,3)dioxolo(4,5-j)phenanthridin-6(2H)-one |
| Purity: | ≥98% (HPLC) |
Soluble guanylyl cyclase (sGC) activator; induces G1 cell cycle arrest
| Chemical Name: | 3-(5'-Hydroxymethyl-2'-furyl)-1-benzyl indazole |
| Purity: | ≥98% (HPLC) |
Cytotoxic agent
| Chemical Name: | N-[4-[[(2,4-Diamino-6-pteridinyl)methyl]methylamino]benzoyl]-L-glutamic acid |
| Purity: | ≥98% (HPLC) |
Potent CDK14 and CDK16 inhibitor; displays reversible inhibition of CDK14
| Chemical Name: | N-(1-((3-(4-(Dimethylamino)butanamido)phenyl)sulfonyl)piperidin-4-yl)-4-(2,4,6-trichlorobenzamido)-1H-pyrazole-3-carboxamide |
| Purity: | ≥98% (HPLC) |
Cdk inhibitor; potently inhibits cdk1, 2, 5 and 9
| Chemical Name: | 4-[2-Methyl-1-(1-methylethyl)-1H-imidazol-5-yl]-N-[4-(methylsulfonyl)phenyl]-2-pyrimidinamine |
| Purity: | ≥98% (HPLC) |
High affinity Bcl-2 family inhibitor; proapoptotic, senolytic and antitumor
| Chemical Name: | 4-[4-[[2-(4-Chlorophenyl)-5,5-dimethyl-1-cyclohexen-1-yl]methyl]-1-piperazinyl]-N-[[4-[[(1R)-3-(4-morpholinyl)-1-[(phenylthio)methyl]propyl]amino]-3-[(trifluoromethyl)sulfonyl]phenyl]sulfonyl]benzamide |
| Purity: | ≥98% (HPLC) |
Selective exportin-1 (XPO1/CRM1) inhibitor
| Chemical Name: | (2Z)-3-[3-[3,5-Bis(trifluoromethyl)phenyl]-1H-1,2,4-triazol-1-yl]-2-propenoic acid 2-(2-pyridinyl)hydrazide |
| Purity: | ≥98% (HPLC) |
Potent and selective Cdc7 inhibitor
| Alternate Names: | BMS 863233 |
| Chemical Name: | 8-Chloro-2-(2S)-2-pyrrolidinylbenzofuro[3,2-d]pyrimidin-4(3H)-one hydrochloride |
| Purity: | ≥98% (HPLC) |
Potent and selective MST3 kinase binding inhibitor
| Chemical Name: | 8-(4-Aminobutyl)-6-[2-chloro-4-(6-methylpyridin-2-yl)phenyl]-2-(1,3-dihydroxypropan-2-ylamino)pyrido[2,3-d]pyrimidin-7-one trihydrochloride |
| Purity: | ≥98% (HPLC) |
Cdk inhibitor
| Alternate Names: | CYC 202,Seliciclib |
| Chemical Name: | (2R)-2-[[9-(1-Methylethyl)-6-[(phenylmethyl)amino]-9H-purin-2-yl]amino]-1-butanol |
| Purity: | ≥98% (HPLC) |
Potent and selective mTOR inhibitor
| Chemical Name: | N-[4-[4-(4-Morpholinyl)-1-[1-(3-pyridinylmethyl)-4-piperidinyl]-1H-pyrazolo[3,4-d]pyrimidin-6-yl]phenyl]-carbamic acid methyl ester dihydrochloride |
| Purity: | ≥98% (HPLC) |
Potent covalent CDK14 and CDK16 inhibitor; also inhibits other TAIRE kinase family members
| Chemical Name: | N-[1-[[3-[[(2E)-4-(Dimethylamino)-1-oxo-2-buten-1-yl]amino]phenyl]sulfonyl]-4-piperidinyl]-4-[(2,4,6- trichlorobenzoyl)amino]-1H-pyrazole-3-carboxamide |
| Purity: | ≥98% (HPLC) |
Potent cdk inhibitor
| Chemical Name: | 3-[[4-[2-[(3-Chlorophenyl)amino]-4-pyrimidinyl]-2-pyridinyl]amino]-1-propanol |
| Purity: | ≥98% (HPLC) |
Inhibits c-Myc-Max dimerization
| Chemical Name: | 5-[(4-Ethylphenyl)methylene]-2-thioxo-4-thiazolidinone |
| Purity: | ≥98% (HPLC) |
