Sign In / Register
Bromodomain Inhibitors: Small Molecules and Peptides
53 results for "Bromodomain Inhibitors Small Molecules and Peptides" in Products
Search
Product Action
Conjugates
Low Endotoxin
Sample Size
Citations
Reviews
Bromodomain Inhibitors: Small Molecules and Peptides
53 results for "Bromodomain Inhibitors Small Molecules and Peptides" in Products
Potent and selective SMARCA4/2 inhibitor
| Chemical Name : | (S)-1-(Methylsulfonyl)-N-[4-(methylthio)-1-oxo-1-[[4-[3-(pyridin-4-yl)phenyl]thiazol-2-yl]amino]butan-2-yl]-1H-pyrrole-3-carboxamide |
| Purity : | ≥95% (HPLC) |
BET bromodomain inhibitor; also promotes differentiation of hiPSCs into megakaryocytes
| Chemical Name : | 7-(3,5-Dimethyl-4-isoxazolyl)-1,3-dihydroxy-8-methoxy-1-[(1R)-1-(2-pyridinyl)ethyl]-2H-imidazo[4,5-c]quinolin-2-one dihydrochloride |
| Purity : | ≥98% (HPLC) |
Potent and selective BET bromodomain inhibitor; cell permeable
| Chemical Name : | (6S)-4-(4-Chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetic acid 1,1-dimethylethyl ester |
| Purity : | ≥98% (HPLC) |
Potent and selective BRD4 Degrader (PROTAC®)
| Chemical Name : | Methyl (6S)-4-(4-chlorophenyl)-2-[[[5-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]pentyl]amino]carbonyl]-3,9-dimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetate |
| Purity : | ≥98% (HPLC) |
Broad spectrum bromodomain inhibitor
| Chemical Name : | N-[(6-3-Methanesulfonamido-4-methylphenyl)-3-methyl-[1,2,4]triazolo[4,3-b]pyridazin-8-yl]carbamate |
| Purity : | ≥98% (HPLC) |
Potent and selective (+)-JQ1 based Degrader (PROTAC®) targeting BET bromodomains, active in vivo
| Chemical Name : | (6S)-4-(4-Chlorophenyl)-N-[8-[[2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]acetyl]amino]octyl]-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetamide |
| Purity : | ≥98% (HPLC) |
Potent and selective BRD1 and TAF1 inhibitor
| Chemical Name : | 6-(3-Hydroxypropyl)-2-(1,3,6-trimethyl-2-oxo-2,3-dihydro-1H-benzimidazol-5-yl)-1H-benzo[de]isoquinoline-1,3(2H)-dione |
| Purity : | ≥98% (HPLC) |
RNA binding protein Lin28 inhibitor; promotes mESC differentiation; also bromodomain inhibitor
| Chemical Name : | N-Methyl-N-[3-(3-methyl-1,2,4-triazolo[4,3-b]pyridazin-6-yl)phenyl]acetamide |
| Purity : | ≥98% (HPLC) |
(+)-JQ1 based Degrader (PROTAC®) that preferentially degrades BRD4
| Chemical Name : | (2S,4R)-1-((S)-2-(tert-butyl)-17-((S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)-4,16-dioxo-6,9,12-trioxa-3,15-diazaheptadecanoyl)- 4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide |
| Purity : | ≥98% (HPLC) |
Potent and selective BRD9 Degrader (PROTAC®)
| Chemical Name : | 2-[[[4-(1,2-Dihydro-2-methyl-1-oxo-2,7-naphthyridin-4-yl)-2-6-dimethoxyphenyl]methyl]methylamino]-N-[2-[2-[2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]ethoxy]ethoxy]ethyl]acetamide dihydrochloride |
| Purity : | ≥98% (HPLC) |
Potent BRD9 Degrader (PROTAC®)
| Chemical Name : | 2-((2,6-Dimethoxy-4-(2-methyl-1-oxo-1,2-dihydro-2,7-naphthyridin-4-yl)benzyl)(methyl)amino)-N-(8-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)octyl)acetamide |
| Purity : | ≥98% (HPLC) |
BET bromodomain inhibitor; orally bioavailable
| Alternate Names : | Birabresib |
| Chemical Name : | (6S)-4-(4-Chlorophenyl)-N-(4-hydroxyphenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetamide |
| Purity : | ≥98% (HPLC) |
Potent and selective BRPF1 inhibitor
| Chemical Name : | N-[2,3-Dihydro-1,3-dimethyl-2-oxo-6-(1-piperidinyl)-1H-benzimidazol-5-yl]-2-methoxybenzamide |
| Purity : | ≥99% (HPLC) |
Selective MLLT1/3 inhibitor
| Chemical Name : | N-[2-[[(2S)-2-Methyl-1-pyrrolidinyl]methyl]-1H-benzimidazol-6-yl]-6-isoquinolinecarboxamide |
| Purity : | ≥98% (HPLC) |
Negative Control for MZ 1 (Cat. No. 6154)
| Chemical Name : | (2S,4S)-1-((S)-2-(tert-butyl)-17-((S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)-4,16-dioxo-6,9,12-trioxa-3,15-diazaheptadecanoyl)- 4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide |
| Purity : | ≥98% (HPLC) |
Potent SMARCA2/4 inhibitor
| Chemical Name : | N-[(1S)-1-(Methoxymethyl)-2-[[4-[3-(1-methyl-1H-pyrazol-3-yl)phenyl]-2-thiazolyl]amino]-2-oxoethyl]-1-(methylsulfonyl)-1H-pyrrole-3-carboxamide |
| Purity : | ≥95% (HPLC) |
Potent and selective BRD7/9 Degrader (PROTAC®)
| Chemical Name : | (2S,4R)-N-(2-((5-(4-(2,6-Dimethoxy-4-(2-methyl-1-oxo-1,2-dihydro-2,7-naphthyridin-4-yl)benzyl)piperazin-1-yl)pentyl)oxy)-4-(4-methylthiazol-5-yl)benzyl)-1-((S)-2-(1-fluorocyclopropane-1-carboxamido)-3,3-dimethylbutanoyl)-4-hydroxypyrrolidine-2-carboxamide |
| Purity : | ≥98% (HPLC) |
Potent CBP/p300 BRD inhibitor
| Chemical Name : | 2-[2-(3-Chloro-4-methoxyphenyl)ethyl]-5-(dimethyl-1,2-oxazol-4-yl)-1-[(2S)-2-(morpholin-4-yl)propyl]-1H-1,3-benzodiazole |
| Purity : | ≥98% (HPLC) |
ERK5/BMK1 inhibitor; also BRD4 inhibitor
| Chemical Name : | 2-[[2-Ethoxy-4-(4-hydroxy-1-piperidinyl)phenyl]amino]-5,11-dihydro-5,11-dimethyl-6H-pyrimido[4,5-b][1,4]benzodiazepin-6-one |
| Purity : | ≥98% (HPLC) |
Selective BRD7 and BRD9 inhibitor
| Chemical Name : | N-[(2R,3S)-2-(4-Chlorophenyl)-1-(1,2-dihydro-1,4-dimethyl-2-oxo-7-quinolinyl)-6-oxo-3-piperidinyl]-2-methyl-1-propanesulfonamide |
| Purity : | ≥98% (HPLC) |
Potent and selective CECR2 inhibitor
| Chemical Name : | N-Cyclopropyl-2-(propylsulfonyl)-6-(1-(2,2,6,6-tetramethylpiperidin-4-yl)-1H-indol-5-yl)pyrimidin-4-amine |
| Purity : | ≥98% (HPLC) |
Potent and selective BRD9 inhibitor
| Chemical Name : | 5-Ethyl-4,5-dihydro-4-oxo-N-(tetrahydro-1,1-dioxido-2H-thiopyran-4-yl)-7-[3-(trifluoromethyl)phenyl]thieno[3,2-c]pyridine-2-carboximidamide |
| Purity : | ≥98% (HPLC) |
BET bromodomain inhibitor
| Chemical Name : | 2-Methoxy-N-(3-methyl-2-oxo-1,2,3,4-tetrahydroquinazolin-6-yl)benzenesulfonamide |
| Purity : | ≥98% (HPLC) |
Potent and selective BRD4(1) inhibitor
| Chemical Name : | (E)-4-[2-(2-Amino-4-hydroxy-5-methylphenyl)diazenyl]-N-2-pyridinylbenzenesulfonamide |
| Purity : | ≥98% (HPLC) |
Selective BRPF1B and BRPF2 inhibitor
| Chemical Name : | 4-Bromo-N-(2,3-dihydro-6-methoxy-1,3-dimethyl-2-oxo-1H-benzimidazol-5-yl)-2-methylbenzenesulfonamide |
| Purity : | ≥98% (HPLC) |
