TP 238
Tocris Bioscience, part of Bio-Techne | Catalog # 6670
CECR2 and BPTF/FALZ inhibitor
Product Description
TP 238 is a cat eye syndrome chromosome region, candidate 2 (CECR2) and bromodomain PHD finger transcription factor (BPTF/FALZ) inhibitor (IC50 values are 10-30 and 100-350 nM, respectively).A concentration of no more than 2 μM is recommended for use in cellular assays.
Licensing Information
This probe is supplied in conjunction with the Structural Genomics Consortium. For further characterization details, please visit the TP 238 probe summary on the SGC website.Product Specifications
Molecular Weight
495.04
Formula
C22H30N6O<sub>3S.HCl
Storage
Store at -20°C
Purity
≥98% (HPLC)
Chemical Name
N-[(3-(1H)-Pyrazol-1-yl)propyl)-6-(4-(3-(dimethylamino)propoxy)phenyl)-2-(methylsulfonyl)pyrimidin-4-amine hydrochloride
CAS Number
2415263-05-5
SMILES
O=S(C1=NC(NCCCN2N=CC=C2)=CC(C3=CC=C(C=C3)OCCCN(C)C)=N1)(C)=O.Cl
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| water | 49.5 | 100 | |
| DMSO | 49.5 | 100 |
Preparing Stock Solutions
for TP 238
The following data is based on the product molecular weight 495.04
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 2.02 mL | 10.10 mL | 20.20 mL |
| 5 mM | 0.40 mL | 2.02 mL | 4.04 mL |
| 10 mM | 0.20 mL | 1.01 mL | 2.02 mL |
| 50 mM | 0.04 mL | 0.20 mL | 0.40 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Product Specific Notices for TP 238
For research use only
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