16 results for "5-HT1B Small Molecules and Peptides" in Products
5-HT1B Small Molecules and Peptides
5-HT1B is a 7TM receptor for serotonin and is expressed on striatal neurons and Purkinje cells in the cerebellum. 5-HT1B ligation inhibits glycinergic signaling, appetite, circadian rhythym light responsiveness, and trigeminal-mediated nociception. It is an important pharmacologic target in the treatment of migrane headaches.
Selective h5-HT1B antagonist
5-HT1B antagonist
5-HT1B agonist
Inhibits calcium-sensitive chloride currents
Potent and selective 5-HT1B agonist
Potent and selective 5-HT1B and 5-HT1D antagonist
5-HT1B agonist
Highly potent 5-HT1B agonist; also 5-HT3 antagonist
5-HT1A and 5-HT1B agonist
5-HT1A and 5-HT1B antagonist; also β-adrenergic antagonist
5-HT1A and 5-HT1B antagonist; also β-adrenergic antagonist
Selective 5-HT3 antagonist
Potent and selective 5-HT7 antagonist; brain penetrant
5-HT1A, 5-HT1B and 5-HT1D agonist
Potent 5-HT7 agonist
5-HT1A, 5-HT1B and 5-HT1D agonist