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5-HT1B Products
5-HT1B is a 7TM receptor for serotonin and is expressed on striatal neurons and Purkinje cells in the cerebellum. 5-HT1B ligation inhibits glycinergic signaling, appetite, circadian rhythym light responsiveness, and trigeminal-mediated nociception. It is an important pharmacologic target in the treatment of migrane headaches.
19 results for "5-HT1B" in Products
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5-HT1B Products
5-HT1B is a 7TM receptor for serotonin and is expressed on striatal neurons and Purkinje cells in the cerebellum. 5-HT1B ligation inhibits glycinergic signaling, appetite, circadian rhythym light responsiveness, and trigeminal-mediated nociception. It is an important pharmacologic target in the treatment of migrane headaches.
19 results for "5-HT1B" in Products
Endogenous 5-HT receptor agonist
| Alternate Names : | 5-Hydroxytryptamine, 5-HT |
| Chemical Name : | 3-(2-Aminoethyl)-1H-indol-5-ol hydrochloride |
| Purity : | ≥99% (HPLC) |
5-HT1B agonist
| Chemical Name : | 7-Trifluoromethyl-4-(4-methyl-1-piperazinyl)pyrrolo[1,2-a]-quinoxaline dimaleate |
| Purity : | ≥98% (HPLC) |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #499325 |
| Applications : | Immunohistochemistry |
5-HT1A, 5-HT1B and 5-HT1D agonist
| Alternate Names : | GR 43175 |
| Chemical Name : | 3-[2-(Dimethylamino)ethyl]-N-methyl-1H-indole-5-methanesulfonamide succinate |
| Purity : | ≥99% (HPLC) |
Non-selective 5-HT, dopamine, adrenalin and histamine receptor antagonist; antipsychotic agent
| Chemical Name : | (3aR*,12bR*)-5-Chloro-2,3,3a,12b-tetrahydro-2-methyl-1H-dibenz[2,3:6,7]oxepino[4,5-c]pyrrole maleate |
| Purity : | ≥98% (HPLC) |
5-HT1B agonist
| Chemical Name : | 1,4-Dihydro-3-(1,2,3,6-tetrahydro-4-pyridinyl)-5H-pyrrol[3,2-b]pyridin-5-one dihydrochloride |
Selective 5-HT1B antagonist
| Chemical Name : | 1'-Methyl-5-[[2'-methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)biphenyl-4-yl]carbonyl]-2,3,6,7-tetrahydrospiro[furo[2,3-f]indole-3,4'-piperidine hydrochloride |
| Purity : | ≥95% (HPLC) |
Potent and selective 5-HT1B agonist
| Chemical Name : | 5-Propoxy-3-(1,2,3,6-tetrahydro-4-pyridinyl)-1H-pyrrolo[3,2-b]pyridine hydrochloride |
| Purity : | ≥98% (HPLC) |
Selective h5-HT1B antagonist
| Chemical Name : | N-[3-[3-(Dimethylamino)ethoxy]-4-methoxyphenyl]-2'-methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)-[1,1'-biphenyl]-4-carboxamide hydrochloride |
| Purity : | ≥98% (HPLC) |
5-HT1B antagonist
| Chemical Name : | 3-[3-(Dimethylamino)propyl]-4-hydroxy-N-[4-(4-pyridinyl)phenyl]benzamide dihydrochloride |
| Purity : | ≥98% (HPLC) |
Highly potent 5-HT1B agonist; also 5-HT3 antagonist
| Chemical Name : | 6-Chloro-2-[piperidinyl-4-thio]pyridine hydrochloride |
| Purity : | ≥99% (HPLC) |
Potent and selective 5-HT1B and 5-HT1D antagonist
| Chemical Name : | N-[4-Methoxy-3-(4-methyl-1-piperazinyl)phenyl]-2'-methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)-1,1'-biphenyl-4-carboxamide hydrochloride |
| Purity : | ≥98% (HPLC) |
Potent 5-HT1B/1D/1F agonist
| Chemical Name : | (4S)-4-((3-(2-(Dimethylamino)ethyl)-1H-indol-5-yl)methyl)-2-oxazolidinone |
| Purity : | ≥99% (HPLC) |
5-HT1A and 5-HT1B antagonist; also β-adrenergic antagonist
| Chemical Name : | 4-[3-[tert-Butylamino]-2-hydroxypropoxy]-1H-indole-2-carbonitrile hemifumarate |
| Purity : | ≥98% (HPLC) |
Inhibits calcium-sensitive chloride currents
| Chemical Name : | 5-Nitro-2-(3-phenylpropylamino)benzoic acid |
| Purity : | ≥99% (HPLC) |
5-HT1A and 5-HT1B agonist
| Chemical Name : | 5-Methoxy-3-(1,2,5,6-tetrahydro-4-pyridinyl)-1H-indole hemisuccinate |
| Purity : | ≥99% (HPLC) |
α partial agonist; also D2-like partial agonist and 5-HT antagonist
| Chemical Name : | 9,10-Dihydro-12'-hydroxy-2'-methyl-5'-(phenylmethyl)ergotaman-3',6',18-trione mesylate |
| Purity : | ≥98% (HPLC) |
Selective 5-ht5a antagonist
| Chemical Name : | N-[2-(Dimethylamino)ethyl]-N-[[4'-[[(2-phenylethyl)amino]methyl][1,1'-biphenyl]-4-yl]methyl]cyclopentanepropanamide dihydrochloride |
| Purity : | ≥99% (HPLC) |
