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16 results for "5-HT1B Small Molecules and Peptides" in Products

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5-HT1B Small Molecules and Peptides

5-HT1B is a 7TM receptor for serotonin and is expressed on striatal neurons and Purkinje cells in the cerebellum. 5-HT1B ligation inhibits glycinergic signaling, appetite, circadian rhythym light responsiveness, and trigeminal-mediated nociception. It is an important pharmacologic target in the treatment of migrane headaches.

SB 216641 hydrochloride

Catalog #: 1242

(1)

Product Documents

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Selective h5-HT1B antagonist

Chemical Name:

N-[3-[3-(Dimethylamino)ethoxy]-4-methoxyphenyl]-2'-methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)-[1,1'-biphenyl]-4-carboxamide hydrochloride

Purity:

≥98%

GR 55562 dihydrochloride

Catalog #: 1054

(1)

Product Documents

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5-HT1B antagonist

Chemical Name:

3-[3-(Dimethylamino)propyl]-4-hydroxy-N-[4-(4-pyridinyl)phenyl]benzamide dihydrochloride

Purity:

≥98%

CP 93129 dihydrochloride

Catalog #: 1032

(3)

Product Documents

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5-HT1B agonist

Chemical Name:

1,4-Dihydro-3-(1,2,3,6-tetrahydro-4-pyridinyl)-5H-pyrrol[3,2-b]pyridin-5-one dihydrochloride

NPPB

Catalog #: 0593

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Product Documents

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Inhibits calcium-sensitive chloride currents

Chemical Name:

5-Nitro-2-(3-phenylpropylamino)benzoic acid

Purity:

≥98%

CP 94253 hydrochloride

Catalog #: 1317

(1)

Product Documents

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Potent and selective 5-HT1B agonist

Chemical Name:

5-Propoxy-3-(1,2,3,6-tetrahydro-4-pyridinyl)-1H-pyrrolo[3,2-b]pyridine hydrochloride

Purity:

≥98%

GR 127935 hydrochloride

Catalog #: 1477

Product Documents

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Potent and selective 5-HT1B and 5-HT1D antagonist

Chemical Name:

N-[4-Methoxy-3-(4-methyl-1-piperazinyl)phenyl]-2'-methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)-1,1'-biphenyl-4-carboxamide hydrochloride

Purity:

≥98%

CGS 12066B dimaleate

Catalog #: 0638

Product Documents

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5-HT1B agonist

Chemical Name:

7-Trifluoromethyl-4-(4-methyl-1-piperazinyl)pyrrolo[1,2-a]-quinoxaline dimaleate

Purity:

≥98%

Anpirtoline hydrochloride

Catalog #: 0703

Product Documents

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Highly potent 5-HT1B agonist; also 5-HT3 antagonist

Chemical Name:

6-Chloro-2-[piperidinyl-4-thio]pyridine hydrochloride

Purity:

≥99%

RU 24969 hemisuccinate

Catalog #: 0912

(1)

Product Documents

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5-HT1A and 5-HT1B agonist

Chemical Name:

5-Methoxy-3-(1,2,5,6-tetrahydro-4-pyridinyl)-1H-indole hemisuccinate

Purity:

≥99%

Cyanopindolol hemifumarate

Catalog #: 0993

Product Documents

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5-HT1A and 5-HT1B antagonist; also β-adrenergic antagonist

Chemical Name:

4-[3-[tert-Butylamino]-2-hydroxypropoxy]-1H-indole-2-carbonitrile hemifumarate

Purity:

≥98%

SB 224289 hydrochloride

Catalog #: 1221

(1)

Product Documents

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Selective 5-HT1B antagonist

Chemical Name:

1'-Methyl-5-[[2'-methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)biphenyl-4-yl]carbonyl]-2,3,6,7-tetrahydrospiro[furo[2,3-f]indole-3,4'-piperidine hydrochloride

Purity:

≥95%

Serotonin hydrochloride

Catalog #: 3547

(1)

Product Documents

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Endogenous 5-HT receptor agonist

Alternate Names:

5-Hydroxytryptamine,5-HT

Chemical Name:

3-(2-Aminoethyl)-1H-indol-5-ol hydrochloride

Purity:

≥98%

SB 699551

Catalog #: 3188

Product Documents

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Selective 5-ht5a antagonist

Chemical Name:

N-[2-(Dimethylamino)ethyl]-N-[[4'-[[(2-phenylethyl)amino]methyl][1,1'-biphenyl]-4-yl]methyl]cyclopentanepropanamide dihydrochloride

Purity:

≥98%

Sumatriptan succinate

Catalog #: 3586

(1)

Product Documents

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5-HT1A, 5-HT1B and 5-HT1D agonist

Alternate Names:

GR 43175

Chemical Name:

3-[2-(Dimethylamino)ethyl]-N-methyl-1H-indole-5-methanesulfonamide succinate

Purity:

≥99%

Flupenthixol dihydrochloride

Catalog #: 4057

Product Documents

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Dopamine antagonist

Alternate Names:

Flupentixol

Chemical Name:

4-[3-[2-(Trifluoromethyl)-9H-thioxanthen-9-ylidene]propyl]-1-piperazineethanol dihydrochloride

Purity:

≥98%

PNU 142633

Catalog #: 1985

Product Documents

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Highly selective 5-HT1D agonist

Chemical Name:

(1S)-1-[2-[4-[4-(Aminocarbonyl)phenyl]-1-piperazinyl]ethyl]-3,4-dihydro-N-methyl-1H-2-benzopyran-6-carboxamide

Purity:

≥98%

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