VE-Cadherin Products
VE-Cadherin, also known as Cadherin-5 and CD144, is a member of the atypical/type II subgroup of Cadherin homophilic adhesion proteins. A 90 kDa portion of the VE-Cadherin ECD can be shed in a metalloproteinase-dependent mechanism and may function as a VE-Cadherin antagonist. VE-Cadherin is expressed on the surface of vascular endothelial cells (EC) from early in embryogenesis through adulthood as well as in the placenta, on hematopoietic cell progenitors, and on a subpopulation of hematopoietic stem cells. It is a major protein component of adherens junctions between cells of the endothelium. VE-Cadherin supports the extension and stabilization of existing vascular sprouts. VE-Cadherin also regulates or is regulated by VEGF R2, type I and type II TGF-beta receptors, and other endothelial junction proteins such as JAM-C, Claudin-5, and N-Cadherin. Elevated levels of soluble VE-Cadherin are found in the serum of myocardial infarction, angina pectoris, rheumatoid arthritis, and colorectal cancer patients.
33 results for "VE-Cadherin" in Products
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VE-Cadherin Products
VE-Cadherin, also known as Cadherin-5 and CD144, is a member of the atypical/type II subgroup of Cadherin homophilic adhesion proteins. A 90 kDa portion of the VE-Cadherin ECD can be shed in a metalloproteinase-dependent mechanism and may function as a VE-Cadherin antagonist. VE-Cadherin is expressed on the surface of vascular endothelial cells (EC) from early in embryogenesis through adulthood as well as in the placenta, on hematopoietic cell progenitors, and on a subpopulation of hematopoietic stem cells. It is a major protein component of adherens junctions between cells of the endothelium. VE-Cadherin supports the extension and stabilization of existing vascular sprouts. VE-Cadherin also regulates or is regulated by VEGF R2, type I and type II TGF-beta receptors, and other endothelial junction proteins such as JAM-C, Claudin-5, and N-Cadherin. Elevated levels of soluble VE-Cadherin are found in the serum of myocardial infarction, angina pectoris, rheumatoid arthritis, and colorectal cancer patients.
33 results for "VE-Cadherin" in Products
Contains 4 membranes-each spotted in duplicate with 84 different cancer-related antibodies
Contains 4 membranes - 2 spotted in duplicate with 62 different non-hematopoietic antibodies and 2 spotted in duplicate with 57 common antibodies
Clonality : | Polyclonal |
Host : | Goat IgG |
Applications : | CyTOF-ready, Flow Cytometry, Immunocytochemistry/Immunofluorescence, Western Blot |
Clonality : | Monoclonal |
Host : | Mouse IgG2b Clone #123413 |
Applications : | CyTOF-ready, Flow Cytometry, Immunocytochemistry/Immunofluorescence, Western Blot |
Source : | NS0 |
Accession # : | 2208309A |
Applications : | Bioactivity |
Clonality : | Polyclonal |
Host : | Goat IgG |
Applications : | Immunohistochemistry, Simple Western, Western Blot |
Clonality : | Monoclonal |
Host : | Mouse IgG2b Clone #123413 |
Applications : | Flow Cytometry |
Sensitivity : | 0.236 ng/mL |
Assay Range : | 1.56 - 100 ng/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma) |
Applications : | ELISA |
Clonality : | Monoclonal |
Host : | Mouse IgG1 Clone #123433 |
Applications : | Western Blot |
Clonality : | Polyclonal |
Host : | Goat IgG |
Applications : | Western Blot |
Clonality : | Monoclonal |
Host : | Mouse IgG2b Clone #123413 |
Applications : | Flow Cytometry |
Clonality : | Monoclonal |
Host : | Mouse IgG2b Clone #123413 |
Applications : | Flow Cytometry |
Clonality : | Monoclonal |
Host : | Mouse IgG2b Clone #123413 |
Applications : | Flow Cytometry |
Clonality : | Monoclonal |
Host : | Mouse IgG2b Clone #123413 |
Applications : | Flow Cytometry |
Clonality : | Monoclonal |
Host : | Rat IgG2b Clone #162709 |
Applications : | Flow Cytometry |
Clonality : | Monoclonal |
Host : | Rat IgG2b Clone #162709 |
Applications : | Flow Cytometry |
Clonality : | Monoclonal |
Host : | Mouse IgG2b Clone #123413 |
Applications : | Flow Cytometry, Western Blot |
Clonality : | Monoclonal |
Host : | Rat IgG2b Clone #162709 |
Applications : | CyTOF-ready, Flow Cytometry, Western Blot |
Assay Range : | 0.312 - 20 ng/mL |
Applications : | ELISA |
Clonality : | Monoclonal |
Host : | Mouse IgG2b Clone #123413 |
Applications : | Flow Cytometry |
Clonality : | Monoclonal |
Host : | Mouse IgG2b Clone #123413 |
Applications : | Flow Cytometry |
Clonality : | Monoclonal |
Host : | Rat IgG2b Clone #162709 |
Applications : | Flow Cytometry |
Source : | NS0 |
Accession # : | P33151 |
Applications : | Bioactivity |
Clonality : | Monoclonal |
Host : | Rat IgG2b Clone #162709 |
Applications : | Flow Cytometry |
Clonality : | Monoclonal |
Host : | Rat IgG2b Clone #162709 |
Applications : | Flow Cytometry |