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S100A8: Antibodies

S100A8 (also MRP8 and calgranulin A) is a 10 kDa member of the S100 family, EF-hand superfamily of Ca-binding proteins. It is produced by neutrophils and monocytes, and forms Ca2+-dependent heterodimer/heterotetramer complexes (termed calprotectin) with S100A9. It functions both intracellularly and extracellularly, where it binds to RAGE and CD36. Human S100A8 is 93 amino acids (aa) in length. It contains two EF-hand motifs (aa 12 - 47 and 46 - 81) and one high-affinity Ca2+-binding site (aa 59 - 70). There may be one splice form that shows a 15 aa substitution for the C-terminal 14 amino acids. Although mouse S100A8 is cleaved by MMP-2 after Asn21, it is unclear if human S100A8 is susceptible. Full-length human S100A8 is 57% and 74% aa identical to mouse and canine S100A8, respectively.

21 results for "S100A8 Primary Antibodies" in Products

S100A8: Antibodies

S100A8 (also MRP8 and calgranulin A) is a 10 kDa member of the S100 family, EF-hand superfamily of Ca-binding proteins. It is produced by neutrophils and monocytes, and forms Ca2+-dependent heterodimer/heterotetramer complexes (termed calprotectin) with S100A9. It functions both intracellularly and extracellularly, where it binds to RAGE and CD36. Human S100A8 is 93 amino acids (aa) in length. It contains two EF-hand motifs (aa 12 - 47 and 46 - 81) and one high-affinity Ca2+-binding site (aa 59 - 70). There may be one splice form that shows a 15 aa substitution for the C-terminal 14 amino acids. Although mouse S100A8 is cleaved by MMP-2 after Asn21, it is unclear if human S100A8 is susceptible. Full-length human S100A8 is 57% and 74% aa identical to mouse and canine S100A8, respectively.

21 results for "S100A8 Primary Antibodies" in Products

WB, Simple Western, ICC
IHC, Dual ISH-IHC, ICC

Recombinant Monoclonal Antibody.

ELISA, IHC, CyTOF-ready, ICFlow
WB, Simple Western, CyTOF-ready, ICC, ICFlow
ELISA, CyTOF-ready, ICFlow
Catalog #: IC45702G
ICFlow
Catalog #: IC45702N
ICFlow
Catalog #: IC45703V
ICFlow
Catalog #: IC45703T
ICFlow
Catalog #: BAF4570
WB
Catalog #: IC45702R
ICFlow
Catalog #: IC45702V
ICFlow
Catalog #: IC45702T
ICFlow
Catalog #: IC45703N
ICFlow
Catalog #: IC45703S
ICFlow
Catalog #: IC45703U
ICFlow
Catalog #: IC45702U
ICFlow
Catalog #: IC45702S
ICFlow
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