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Poly(ADP-ribose) Polymerase Inhibitors Products

PARP [Poly(ADP-ribose) Polymerase], also known as ADPRT and PPOL, is a 118-kDa enzyme that uses NAD as a substrate to catalyze the covalent transfer of ADP-ribose to a variety of nuclear protein acceptors. ADP ribosyltransferase is required for cellular repair, and PARP expression is induced by single-strand breaks in DNA. PARP is proteolytically cleaved by Caspase-3 into two fragments of 89- and 24-kDa in one of the hallmark events of apoptosis.

18 results for "Poly(ADP-ribose) Polymerase Inhibitors" in Products

Poly(ADP-ribose) Polymerase Inhibitors Products

PARP [Poly(ADP-ribose) Polymerase], also known as ADPRT and PPOL, is a 118-kDa enzyme that uses NAD as a substrate to catalyze the covalent transfer of ADP-ribose to a variety of nuclear protein acceptors. ADP ribosyltransferase is required for cellular repair, and PARP expression is induced by single-strand breaks in DNA. PARP is proteolytically cleaved by Caspase-3 into two fragments of 89- and 24-kDa in one of the hallmark events of apoptosis.

18 results for "Poly(ADP-ribose) Polymerase Inhibitors" in Products

Potent fluorescent PARP inhibitor; cell permeable

Potent PARP inhibitor

Potent tankyrase inhibitor

PARP-1 inhibitor

Potent PARP inhibitor

PARP inhibitor; cytoprotectant

PARP inhibitor

Selective allosteric PARP14 inhibitor

PARP14 inhibitor; cell-permeable

Potent PARP-1 inhibitor

Tankyrase inhibitor

PARP inhibitor

Potent tankyrase inhibitor

WIKI4 synthesized to Ancillary Material Grade

Selective PARP-10 inhibitor

PARP inhibitor; photoaffinity probe

High affinity PARP-1 and -2 inhibitor; orally bioavailable

Potent PARP inhibitor; orally bioavailable

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