15 results for "Poly(ADP-ribose) Polymerase Inhibitors Small Molecules and Peptides" in Products
Poly(ADP-ribose) Polymerase Inhibitors: Small Molecules and Peptides
Potent tankyrase inhibitor
| Alternate Names: | XAV939 Wnt Signaling Inhibitor |
| Chemical Name: | 3,5,7,8-Tetrahydro-2-[4-(trifluoromethyl)phenyl]-4H-thiopyrano[4,3-d]pyrimidin-4-one |
| Purity: | ≥98% (HPLC) |
PARP-1 inhibitor
| Chemical Name: | Pyridine-3-carboxamide |
| Purity: | ≥99% (HPLC) |
Potent PARP inhibitor
| Chemical Name: | 4-[[3-[[4-(Cyclopropylcarbonyl)-1-piperazinyl]carbonyl]-4-fluorophenyl]methyl]-1(2H)-phthalazinone |
| Purity: | ≥98% (HPLC) |
Potent PARP-1 inhibitor
| Chemical Name: | 5'-Deoxy-5'-[4-[2-[(2,3-Dihydro-1-oxo-1H-isoindol-4-yl)amino]-2-oxoethyl]-1-piperazinyl]-5'-oxoadenosine dihydrochloride |
| Purity: | ≥98% (HPLC) |
Potent PARP inhibitor; orally bioavailable
| Chemical Name: | 4-[[4-Fluoro-3-[(4-methoxy-1-piperidinyl)carbonyl]phenyl]methyl]-1(2H)-phthalazinone |
| Purity: | ≥98% (HPLC) |
Potent PARP inhibitor
| Chemical Name: | N-(5,6-Dihydro-6-oxo-2-phenanthridinyl)-2-acetamide hydrochloride |
| Purity: | ≥98% (HPLC) |
Potent and selective PARP7 inhibitor; induces antitumor immunity.
| Chemical Name: | 5-[[(1S)-1-Methyl-2-[3-oxo-3-[4-[5-(trifluoromethyl)-2-pyrimidinyl]-1-piperazinyl]propoxy]ethyl]amino]-4-(trifluoromethyl)-3(2H)-pyridazinone |
| Purity: | ≥98% (HPLC) |
Potent tankyrase inhibitor
| Chemical Name: | 2-[3-[[4-(4-Methoxyphenyl)-5-(4-pyridinyl)-4H-1,2,4-triazol-3-yl]thio]propyl]-1H-benz[de]isoquinoline-1,3(2H)-dione |
| Purity: | ≥98% (HPLC) |
PARP inhibitor; cytoprotectant
| Chemical Name: | N-[2-Hydroxy-3-(1-piperidinyl)propoxy]-3-pyridinecarboximidamide dihydrochloride |
| Purity: | ≥98% (HPLC) |
High affinity PARP-1 and -2 inhibitor; orally bioavailable
| Alternate Names: | ABT-888 |
| Chemical Name: | 2-[(2R)-2-Methyl-2-pyrrolidinyl]-1H-benzimidazole-4-carboxamide dihydrochloride |
| Purity: | ≥98% (HPLC) |
Nicotinamide synthesized to Ancillary Material Grade
| Chemical Name: | Pyridine-3-carboxamide |
| Purity: | ≥99% |
PARP inhibitor
| Alternate Names: | CO-338 |
| Chemical Name: | 8-Fluoro-1,3,4,5-tetrahydro-2-[4-[(methylamino)methyl]phenyl]-6H-pyrrolo[4,3,2,ef][2]benzazepin-6-one (1S,4R)-7,7-dimethyl-2-oxobicyclo[2.2.1]heptane-1-methanesulfonic acid |
| Purity: | ≥98% (HPLC) |
PARP inhibitor; photoaffinity probe
| Chemical Name: | 3-(3-Butyn-1-yl)-N-[5-cyano-6-[4-[3-[(3,4-dihydro-4-oxo-1-phthalazinyl)methyl]benzoyl]-1-piperazinyl]-3-pyridinyl]-3H-diazirine-3-propanamide |
| Purity: | ≥95% (HPLC) |
Selective PARP-10 inhibitor
| Chemical Name: | 4,4'-Oxybis[benzamide] |
| Purity: | ≥98% (HPLC) |
Selective allosteric PARP14 inhibitor
| Chemical Name: | N-[2-(9H-Carbazol-1-yl)phenyl]acetamide |
| Purity: | ≥98% (HPLC) |
