1 result for "Poly(ADP-ribose) Polymerase Inhibitors Fluorescent Probes and Dyes" in Products
Poly(ADP-ribose) Polymerase Inhibitors: Fluorescent Probes and Dyes
Poly (ADP-ribose) polymerase (PARP) catalyzes the post-translational modification of proteins by the addition of multiple ADP-ribose moieties. PARP transfers ADP-ribose from nicotinamide dinucleotide (NAD) to Glu/Asp residues on the substrate protein, and also polymerizes ADP-ribose to form long/branched chain polymers. Tankyrase proteins also display PARP activity.
PARP-1, one of 5 confirmed PARPs, is the most abundant and highly expressed PARP enzyme. PARP-1 detects and relocates to single ...
Potent fluorescent PARP inhibitor; cell permeable
| Alternate Names: | AZD2281-BDY FL,Olaparib-BDY FL |
| Chemical Name: | (T-4)-[4-[[3-[[4-[3-[5-[(3,5-Dimethyl-2H-pyrrol-2-ylidene-κN)methyl]-1H-pyrrol-2-yl-κN-1-oxopropyl]-1-piperazinyl]carbonyl]-4-fluorophenyl]methyl]-1(2H)-phthalazinonato]difluoroboron |
| Purity: | ≥90% (HPLC) |
