PDGF Receptor Inhibitors: Small Molecules and Peptides
13 results for "PDGF Receptor Inhibitors Small Molecules and Peptides" in Products
13 results for "PDGF Receptor Inhibitors Small Molecules and Peptides" in Products
PDGF Receptor Inhibitors: Small Molecules and Peptides
Potent VEGFR, PDGFR and FGFR inhibitor
| Chemical Name: | Methyl (Z)-3-[[[4-(N-methyl-2-(4-methylpiperazin-1-yl)acetamido)phenyl)amino)(phenyl)methylene]-2-oxoindoline-6-carboxylate |
| Purity: | ≥98% |
Potent inhibitor of PDGFRβ, KDR, FLT3 and CSF-1R
| Chemical Name: | N-[4-(3-Amino-1H-indazol-4-yl)phenyl]-N'-(2-fluoro-5-methylphenyl)urea |
| Purity: | ≥98% (HPLC) |
PDGFRβ, B-Raf, c-Raf, FLT3 and KIT inhibitor
| Chemical Name: | 2-(Methylthio)-6-[4-[5-[[3-(trifluoromethyl)phenyl]amino]-1H-1,2,4-triazol-3-yl]phenoxy]-4-pyrimidinamine |
| Purity: | ≥98% (HPLC) |
Potent Raf-1 inhibitor; also inhibits VEGFR-2, VEGFR-3, PDGFR-β, Flt-3 and cKIT
| Chemical Name: | 4-[4-[[[[4-Chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]phenoxy]-N-methyl-2-pyridinecarboxamide |
| Purity: | ≥98% (HPLC) |
Potent VEGFR, PDGFRβ and KIT inhibitor
| Alternate Names: | SU 11248 |
| Chemical Name: | N-[2-(Diethylamino)ethyl]-5-[(Z)-(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidine)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide (2S)-2-hydroxybutanedioate salt |
| Purity: | ≥98% (HPLC) |
Potent colony-stimulating factor 1 receptor (CSF-1R) tyroine kinase inhibitor
| Chemical Name: | 4-[(4-Methyl-1-piperazinyl)methyl]-N-[4-methyl-3-[[4-(3-pyridinyl)-2-thiazolyl]amino]phenyl]benzamide |
| Purity: | ≥98% (HPLC) |
Potent and selective v-Abl tyrosine kinase inhibitor; also inhibits PDGFR and c-kit
| Alternate Names: | Gleevec,CGP 57148B |
| Chemical Name: | 4-[(4-Methyl-1-piperazinyl)methyl]-N-[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]benzamide methanesulfonate |
| Purity: | ≥98% (HPLC) |
Potent Src inhibitor; also inhibits FGFR1, PDGFRβ and Wee1
| Chemical Name: | 6-(2,6-Dichlorophenyl)-2-[[4-[2-(diethylamino)ethoxy]phenyl]amino]-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one dihydrochloride |
| Purity: | ≥98% (HPLC) |
Potent and selective PDGFRβ inhibitor
| Chemical Name: | 5-[1,2-Dihydro-2-oxo-6-phenyl-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-propanoic acid |
| Purity: | ≥98% (HPLC) |
Potent and selective PDGFR inhibitor
| Chemical Name: | 1-[2-[5-(2-Methoxyethoxy)-1H-benzimidazol-1-yl]-8-quinolinyl]-4-piperidinamine |
| Purity: | ≥98% (HPLC) |
Potent inhibitor of VEGFR, PDGFR and FGFR
| Chemical Name: | 4-[(4-Fluoro-2-methyl-1H-indol-5-yl)oxy]-6-methoxy-7-[3-(1-pyrrolidinyl)propoxy]quinazoline |
| Purity: | ≥98% (HPLC) |
Potent and selective PDGFR family inhibitor
| Chemical Name: | N-[4-[[[[5-(1,1-Dimethethylethyl)-3-isoxazolyl]amino]carbonyl]amino]phenyl]-5-[(1-ethyl-2,2,6,6-tetramethyl-4-piperidinyl)oxy]-2-pyridinecarboxamide |
| Purity: | ≥98% (HPLC) |
Potent multi-kinase and pan-Bcr-Abl inhibitor
| Alternate Names: | Ponatinib |
| Chemical Name: | 3-(2-Imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-[4-[(4-methyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]-benzamide |
| Purity: | ≥98% (HPLC) |