Key Product Details
Description: | Potent multi-kinase and pan-Bcr-Abl inhibitor |
Alternative Names: | Ponatinib |
Chemical Name: | 3-(2-Imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-[4-[(4-methyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]-benzamide |
Purity: | ≥98% (HPLC) |
Molecular Weight: | 532.56 |
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Citations for AP 24534 (4)
Citations are publications that use Bio-Techne products. Selected citations for AP 24534 include:
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Merkulova et al.
(2019)
Ponatinib treatment promotes arterial thrombosis and hyperactive platelets.
Blood Adv.
3:2312
PMID: 31383636 -
Kim et al.
(2018)
Voltage-dependent Ca2+ channels promote branching morphogenesis of salivary glands by patterning differential growth.
Sci Rep.
8:7566
PMID: 29765108 -
Wong et al.
(2014)
Production of IL-1β by bone marrow-derived macrophages in response to chemotherapeutic drugs: synergistic effects of dox. and vincri.
Cancer Biol Ther.
15:1395
PMID: 25046000 -
Wong et al.
(2013)
Small molecule kinase inhibitors block the ZAK-dependent inflammatory effects of dox.
Cancer Biol Ther.
14:56
PMID: 23114643
There are no citations that match your criteria.