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mGluR5 Products
Human metabotropic glutamate receptor 5 (mGluR5; also mGluR5b) is a 150 kDa, 7-transmembrane glycoprotein that belongs to group I of the C-family of G-protein coupled receptors. mGluR5 is constitutively expressed and regulates neuronal ion channel activity. Human mGluR5 is 1212 amino acids (aa) in length and contains an extracellular domain (ECD) of 558 amino acids. Through its ECD, mGluR5 either homodimerizes or heterodimerizes with the Ca2+-sensor receptor. There is one alternate splice form (mGluR5a) that shows a 32 aa deletion between aa 877 - 908 in the cytoplasmic tail. Over aa 19 - 509, human mGluR5 is 98% aa identical to mouse, rat, and canine mGluR5.
34 results for "mGluR5" in Products
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mGluR5 Products
Human metabotropic glutamate receptor 5 (mGluR5; also mGluR5b) is a 150 kDa, 7-transmembrane glycoprotein that belongs to group I of the C-family of G-protein coupled receptors. mGluR5 is constitutively expressed and regulates neuronal ion channel activity. Human mGluR5 is 1212 amino acids (aa) in length and contains an extracellular domain (ECD) of 558 amino acids. Through its ECD, mGluR5 either homodimerizes or heterodimerizes with the Ca2+-sensor receptor. There is one alternate splice form (mGluR5a) that shows a 32 aa deletion between aa 877 - 908 in the cytoplasmic tail. Over aa 19 - 509, human mGluR5 is 98% aa identical to mouse, rat, and canine mGluR5.
34 results for "mGluR5" in Products
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #464818 |
| Applications : | CyTOF-ready, Flow Cytometry, Western Blot |
| Clonality : | Polyclonal |
| Host : | Rabbit IgG |
| Applications : | Immunohistochemistry, Western Blot |
| Clonality : | Monoclonal |
| Host : | Mouse IgG2b Clone #464823 |
| Applications : | Immunohistochemistry |
| Clonality : | Polyclonal |
| Host : | Sheep IgG |
| Applications : | Immunohistochemistry, Western Blot |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #464818 |
| Applications : | Flow Cytometry |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #464818 |
| Applications : | Flow Cytometry |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #464818 |
| Applications : | Flow Cytometry |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #464818 |
| Applications : | Flow Cytometry |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #464818 |
| Applications : | Flow Cytometry |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #464818 |
| Applications : | Flow Cytometry |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #464818 |
| Applications : | Flow Cytometry |
Potent mGlu5 antagonist; also positive allosteric modulator of mGlu4 receptors
| Chemical Name : | 2-Methyl-6-(phenylethynyl)pyridine hydrochloride |
| Purity : | ≥99% (HPLC) |
Negative allosteric modulator of mGlu5 receptors
| Alternate Names : | Raseglurant |
| Chemical Name : | 2-[(3-Fluorophenyl)ethynyl]-4,6-dimethyl-3-pyridinamine hydrochloride |
| Purity : | ≥99% (HPLC) |
High affinity human mGlu5 antagonist
| Chemical Name : | 3-[2-(6-Methyl-2-pyridinyl)ethynyl]-2-cyclohexene-1-one O-methyloxime |
| Purity : | ≥98% (HPLC) |
Selective mGlu5 agonist; sodium salt of CHPG (Cat. No. 1049)
| Chemical Name : | (RS)-2-Chloro-5-hydroxyphenylglycine sodium salt |
| Purity : | ≥99% (HPLC) |
Potent and selective mGlu5 negative allosteric modulator (NAM)
| Chemical Name : | N-(3-Chlorophenyl)-N'-(4,5-dihydro-1-methyl-4-oxo-1H-imidazol-2-yl)urea |
| Purity : | ≥99% (HPLC) |
Potent group I mGlu antagonist
| Chemical Name : | N-Phenyl-7-(hydroxyimino)cyclopropa[b]chromen-1a-carboxamide |
| Purity : | ≥98% (HPLC) |
Positive allosteric modulator of mGlu5 receptors
| Chemical Name : | N-Cyclobutyl-6-[2-(3-fluorophenyl)ethynyl]-3-pyridinecarboxamide hydrochloride |
| Purity : | ≥98% (HPLC) |
mGlu5 selective agonist
| Chemical Name : | (RS)-2-Chloro-5-hydroxyphenylglycine |
| Purity : | ≥99% (HPLC) |
Potent and selective mGlu5 antagonist
| Chemical Name : | 3-((2-Methyl-1,3-thiazol-4-yl)ethynyl)pyridine hydrochloride |
| Purity : | ≥99% (HPLC) |
Active metabolite of oxcarbazepine (Cat. No. 3864)
| Alternate Names : | GP 47779 |
| Chemical Name : | 10,11-Dihydro-10-hydroxy-5H-dibenz(Z)[b,f]azepin-5-carboxamide |
| Purity : | ≥98% (HPLC) |
AMPA agonist; also group I mGlu agonist
| Chemical Name : | (L)-(+)-α-Amino-3,5-dioxo-1,2,4-oxadiazolidine-2-propanoic acid |
| Purity : | ≥99% (HPLC) |
Positive allosteric modulator of group I mGlu receptors
| Chemical Name : | (9H-Xanthen-9-ylcarbonyl)-carbamic acid butyl ester |
| Purity : | ≥99% (HPLC) |
