ADX 10059 hydrochloride

Tocris Bioscience, part of Bio-Techne | Catalog # 4416

Negative allosteric modulator of mGlu5 receptors
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Key Product Details

Description

Negative allosteric modulator of mGlu5 receptors

Alternative Names

Raseglurant

View all Group I mGluR Modulators »

Product Description

ADX 10059 hydrochloride is reported to be a negative allosteric modulator at the mGlu5 receptor. Analog of MPEP (Cat. No. 1212).

Product Specifications

Molecular Weight

276.74

Formula

C15H13FN2.HCl

Storage

Desiccate at RT

Purity

≥98% (HPLC)

Chemical Name

2-[(3-Fluorophenyl)ethynyl]-4,6-dimethyl-3-pyridinamine hydrochloride

CAS Number

757949-98-7

PubChem ID

18454771

InChI Key

BDXXMGYKLQZXOU-UHFFFAOYSA-N

SMILES

CC1=CC(C)=NC(C#CC2=CC=CC(F)=C2)=C1N.Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 6.92 25
DMSO 27.67 100

Preparing Stock Solutions for ADX 10059 hydrochloride

The following data is based on the product molecular weight 276.74

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 3.61 mL 18.07 mL 36.14 mL
5 mM 0.72 mL 3.61 mL 7.23 mL
10 mM 0.36 mL 1.81 mL 3.61 mL
50 mM 0.07 mL 0.36 mL 0.72 mL

Calculators

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Reconstitution Calculator

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Background References

References are publications that support the biological activity of the product.

Product Documents for ADX 10059 hydrochloride

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for ADX 10059 hydrochloride

For research use only

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