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8 results for "Kir6.1 Small Molecules and Peptides" in Products

Kir6.1: Small Molecules and Peptides

The Kir6.1 (KCNJ8) gene is essential in membrane function as it encodes an inward-rectifier potassium channel protein that is 424 amino acids long and has a mass of nearly 48 kDA. Dysfunctions in the Kir6.1 gene may be a cause of J-wave syndromes and sudden infant death syndrome (SIDS). Research is investigating its role in various diseases such as retinitis, hypoxia, pancreatitis, myocardial infarction, spasticity, leiomyoma, acute myocardial infarction, and prinzmetal angina. The Kir6.1 gene ...

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H1 antagonist. Also KV11.1 (hERG) and Kir6 (KATP) channel blocker

Chemical Name: α-[4-(1,1-Dimethylethyl)phenyl]-4-(hydroxydiphenylmethyl)-1-piperidinebutanol
Purity: ≥98% (HPLC)
H1 antagonist. Also KV11.1 (hERG) and Kir6 (KATP) channel blocker

Kir6 (KATP) blocker; displays high affinity for SUR1/Kir6.2 channels

Alternate Names: A-4166,Senaglinide
Chemical Name: N-[[4-(1-Methylethyl)cyclohexyl]carbonyl]-D-phenylalanine
Kir6 (KATP) blocker; displays high affinity for SUR1/Kir6.2 channels

Kir6 (KATP) channel blocker

Alternate Names: Glyburide
Chemical Name: 5-Chloro-N-[2-[4-[[[(Cylcohexylamino)carbonyl]amino]sulphonyl]phenyl]ethyl]-2-methoxybenzamide
Purity: ≥98% (HPLC)
Kir6 (KATP) channel blocker

Selective inhibitor of Kir6.1 KATP channels

Chemical Name: 1-[(4-Methyl-2-thiophen-2-yl-1,3-thiazol-5-yl)methyl]-3-thiophen-2-ylurea
Purity: ≥98% (HPLC)
Selective inhibitor of Kir6.1 KATP channels

Kir6 (KATP) channel blocker

Alternate Names: AG-EE 623ZW
Chemical Name: 2-Ethoxy-4-[2-[[(1S)-3-methyl-1-[2-(1-piperidinyl)phenyl]butyl]amino]-2-oxoethyl]benzoic acid
Purity: ≥98% (HPLC)
Kir6 (KATP) channel blocker

Kir6 channel (KATP) opener

Chemical Name: 6-(1-Piperidinyl)-2,4-pyrimidinediamine 3-oxide
Purity: ≥98% (HPLC)
Kir6 channel (KATP) opener

Kir6 (KATP) channel opener; active enantiomer of Cromakalim

Alternate Names: BRL 38227
Chemical Name: (3S,4R)-3,4-dihydro-3-hydroxy-2,2-dimethyl-4-(2-oxo-1-pyrrolidinyl)-2H-1-benzopyran-6-carbonitrile
Purity: ≥98% (HPLC)
Kir6 (KATP) channel opener; active enantiomer of Cromakalim

Antianginal, activates pyruvate dehydrogenase

Alternate Names: RS 43285
Chemical Name: N-(2,6-Dimethylphenyl)-4-[2-hydroxy-3-(2-methoxyphenoxy)propyl]-1-piperazineacetamide dihydrochloride
Purity: ≥98% (HPLC)
Antianginal, activates pyruvate dehydrogenase
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