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Ranolazine dihydrochloride

Tocris Bioscience a Bio-Techne Brand

Ranolazine dihydrochloride | CAS No. 95635-56-6 | Antianginal, activates pyruvate dehydrogenase
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Key Product Details

Description: Antianginal, activates pyruvate dehydrogenase
Alternative Names: RS 43285
Chemical Name: N-(2,6-Dimethylphenyl)-4-[2-hydroxy-3-(2-methoxyphenoxy)propyl]-1-piperazineacetamide dihydrochloride
Purity: ≥98% (HPLC)
Molecular Weight: 500.46

Citations for Ranolazine dihydrochloride (3)

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Customer Reviews for Ranolazine dihydrochloride (2)

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  • Reversal of HOCl-LDL induced arrhythmia by ranolazine superfusion
    Name: Chintan Koyani
    Species: Other
    Assay Type: In Vitro
    Cell Line/Tissue: Cardiomyocytes
    Guinea pig ventricular cardiomyocytes were treated (12-16 h) with HOCl-LDL (250 µg/ml). Cells were patched and stimulated at a frequency of 1 Hz. Representative action potentials (shown in Image) recorded in the same cell are shown before (A) and after (B) superfusion with Ranolazine (10 µM, 5 min). For comparative purpose representative APs of a control cardiomyocyte are shown (C).
    Ranolazine dihydrochloride Serum 3118
  • Ranolazine to block fatty acid oxidation
    Name: Anonymous
    Species: Mouse
    Assay Type: Ex Vivo
    Cell Line/Tissue: Brain slice
    Application of Ranolazine on acute brain slices to verify for fatty acid oxidation involvement in studied process. It had the same effect as etomoxir (CPT1 blocker), as expected per hypothesis.

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Product Documents for Ranolazine dihydrochloride

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