Ranolazine dihydrochloride
Tocris Bioscience a Bio-Techne Brand
Key Product Details
Description: | Antianginal, activates pyruvate dehydrogenase |
Alternative Names: | RS 43285 |
Chemical Name: | N-(2,6-Dimethylphenyl)-4-[2-hydroxy-3-(2-methoxyphenoxy)propyl]-1-piperazineacetamide dihydrochloride |
Purity: | ≥98% (HPLC) |
Molecular Weight: | 500.46 |
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Citations for Ranolazine dihydrochloride (3)
Citations are publications that use Bio-Techne products. Selected citations for Ranolazine dihydrochloride include:
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Carstensen et al.
(2019)
Effects of UK 68798 and RS 43285 on atrial fibrillatory rate in a horse model of acutely induced atrial fibrillation.
J Cardiovasc Electrophysiol.
30:596
PMID: 30661267 -
McKeithan et al.
(2017)
An Automated Platform for Assessment of Congenital and Drug-Induced Arrhythmia with hiPSC-Derived Cardiomyocytes.
Front Physiol.
8:766
PMID: 29075196 -
Park et al.
(2013)
Slowly inactivating component of Na+ current in peri-somatic region of hippocampal CA1 pyramidal neurons.
J Neurophysiol.
109:1378
PMID: 23236005
There are no citations that match your criteria.
Customer Reviews for Ranolazine dihydrochloride (2)
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Species: OtherAssay Type: In VitroCell Line/Tissue: CardiomyocytesGuinea pig ventricular cardiomyocytes were treated (12-16 h) with HOCl-LDL (250 µg/ml). Cells were patched and stimulated at a frequency of 1 Hz. Representative action potentials (shown in Image) recorded in the same cell are shown before (A) and after (B) superfusion with Ranolazine (10 µM, 5 min). For comparative purpose representative APs of a control cardiomyocyte are shown (C).
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Species: MouseAssay Type: Ex VivoCell Line/Tissue: Brain sliceApplication of Ranolazine on acute brain slices to verify for fatty acid oxidation involvement in studied process. It had the same effect as etomoxir (CPT1 blocker), as expected per hypothesis.
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